3-Chloro-2-fluoroaniline

Suppliers

Names

[ CAS No. ]:
2106-04-9

[ Name ]:
3-Chloro-2-fluoroaniline

[Synonym ]:
3-Chloro-2-fluorobenzenamine
3-chloro-fluoroaniline
MFCD00069415
Benzenamine, 3-chloro-2-fluoro-
3-chloro-2-fluorophenylamine
2-fluoro-3-chloraniline
3-chloro-2-fluoraniline
3-Chloro-2-fluoroaniline
ZR CG BF
EINECS 218-283-6
3-chloro-2-fluoro-aniline
2-fluoro-3-chloroaniline

Chemical & Physical Properties

[ Density]:
1.3±0.1 g/cm3

[ Boiling Point ]:
218.6±20.0 °C at 760 mmHg

[ Molecular Formula ]:
C6H5ClFN

[ Molecular Weight ]:
145.562

[ Flash Point ]:
86.0±21.8 °C

[ Exact Mass ]:
145.009460

[ PSA ]:
26.02000

[ LogP ]:
2.26

[ Vapour Pressure ]:
0.1±0.4 mmHg at 25°C

[ Index of Refraction ]:
1.570

MSDS

Click to get detail MSDS

Safety Information

[ Symbol ]:

GHS05, GHS07

[ Signal Word ]:
Danger

[ Hazard Statements ]:
H302-H315-H318-H335

[ Precautionary Statements ]:
P261-P280-P305 + P351 + P338

[ Personal Protective Equipment ]:
Eyeshields;Faceshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter

[ Hazard Codes ]:
Xn:Harmful;

[ Risk Phrases ]:
R20/21/22;R36/37/38

[ Safety Phrases ]:
S26-S36-S36/37/39-S39

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

[ HS Code ]:
2921420090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • 3-Chloro-2-fluoronitrobenzene
  • dichloronitrobenzene

DownStream

  • Carbanilic acid,3-chloro-2-fluoro-, ethyl ester (7CI,8CI)
  • 3-Amino-2-fluorobenzonitrile
  • 4-Amino-2-chloro-3-fluorobenzonitrile
  • 1-Bromo-3-chloro-2-fluorobenzene
  • 4-Bromo-3-chloro-2-fluoroaniline
  • 3-Chloro-2-fluorophenol
  • 7-chloro-1-ethyl-8-fluoro-4-oxoquinoline-3-carboxylic acid
  • 7-Chloro-8-fluoro-2-phenylquinoline
  • 4-Bromo-7-chloro-8-fluoro-2-phenylquinoline
  • 2-(3-chloro-2-fluoro-phenoxy)acetic acid

Customs

[ HS Code ]: 2921420090

[ Summary ]:
HS:2921420090 aniline derivatives and their salts VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:30.0%

Articles

The first radiosynthesis of [(11)C]AZD8931 as a new potential PET agent for imaging of EGFR, HER2 and HER3 signaling.

Bioorg. Med. Chem. Lett. 24(18) , 4455-9, (2014)

The reference standard AZD8931{2-(4-((4-((3-chloro-2-fluorophenyl)amino)-7-methoxyquinazolin-6-yl)oxy)piperidin-1-yl)-N-methylacetamide} (11a) was synthesized from methyl 4,5-dimethoxy-2-nitrobenzoate...

Yaws CL.

Thermophysical Properties of Chemicals and Hydrocarbons 2nd ed.,, (2014), 522

Synthesis of 2-Chloro-3-fluorobromobenzene [J]. Zhao HY and Pan YQ

Chem. World 11 , 010, (2011)


More Articles

Related Compounds

  • (1H-indol-2-yl)(3-(2-methyl-1H-benzo[d]imidazol-1-yl)pyrrolidin-1-yl)methanone
  • (7-methoxybenzofuran-2-yl)(3-(2-methyl-1H-benzo[d]imidazol-1-yl)pyrrolidin-1-yl)methanone
  • methyl 4-(3-(2-methyl-1H-benzo[d]imidazol-1-yl)pyrrolidine-1-carbonyl)benzoate
  • (5-bromopyridin-3-yl)(3-(2-methyl-1H-benzo[d]imidazol-1-yl)pyrrolidin-1-yl)methanone
  • (2,5-dimethylphenyl)(3-(2-methyl-1H-benzo[d]imidazol-1-yl)pyrrolidin-1-yl)methanone
  • (4-ethoxyphenyl)(3-(2-methyl-1H-benzo[d]imidazol-1-yl)pyrrolidin-1-yl)methanone
  • (2-chlorophenyl)(3-(2-methyl-1H-benzo[d]imidazol-1-yl)pyrrolidin-1-yl)methanone
  • (2-bromophenyl)(3-(2-methyl-1H-benzo[d]imidazol-1-yl)pyrrolidin-1-yl)methanone
  • 3-methoxy-1-(3-(2-methyl-1H-benzo[d]imidazol-1-yl)pyrrolidin-1-yl)propan-1-one
  • (3-(2-methyl-1H-benzo[d]imidazol-1-yl)pyrrolidin-1-yl)(4-(trifluoromethyl)phenyl)methanone
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