Amidinothiourea

Suppliers

Names

[ Name ]:
Amidinothiourea

[Synonym ]:
Guthimin
MFCD00014472
2-imino-4-thiobiuret
Amidinothiourea
EINECS 218-308-0
1-Carbamimidoylthiourea
Thiourea, (aminoiminomethyl)-
Gutimine
N-Amidinothiourea
1-[Amino(imino)methyl]thiourea
Guthimine
Thiodicyanodiamidine
Thiourea,(aminoiminomethyl)
Thiourea, N-(aminoiminomethyl)-
1-Amidinothiourea
Guanylthiourea

Chemical & Physical Properties

[ Density]:
1.7±0.1 g/cm3

[ Boiling Point ]:
231.2±23.0 °C at 760 mmHg

[ Melting Point ]:
171-173 °C(lit.)

[ Molecular Formula ]:
C₂H₆N₄S

[ Molecular Weight ]:
118.161

[ Flash Point ]:
93.7±22.6 °C

[ Exact Mass ]:
118.031319

[ PSA ]:
120.01000

[ LogP ]:
-1.77

[ Vapour Pressure ]:
0.1±0.5 mmHg at 25°C

[ Index of Refraction ]:
1.756

[ Water Solubility ]:
7 g/100 mL (20 ºC)

MSDS

Click to get detail MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: YR8250000

CHEMICAL NAME :: Urea, 1-amidino-2-thio-

CAS REGISTRY NUMBER :: 2114-02-5

LAST UPDATED :: 199406

DATA ITEMS CITED :: 1

MOLECULAR FORMULA :: C2-H6-N4-S

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD - Lethal dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: >500 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: NCNSA6 National Academy of Sciences, National Research Council, Chemical-Biological Coordination Center, Review. (Washington, DC) Volume(issue)/page/year: 5,46,1953

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H315-H319-H335

[ Precautionary Statements ]:
P261-P305 + P351 + P338

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves

[ Hazard Codes ]:
Xn:Harmful

[ Risk Phrases ]:
R20/21/22

[ Safety Phrases ]:
S26-S37/39-S24/25-S23

[ RIDADR ]:
2811

[ WGK Germany ]:
3

[ RTECS ]:
YR8250000

[ Packaging Group ]:
III

[ HS Code ]:
2930909090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Guanidine, (4-phenyl-2-thiazolyl)-
Bis(tributylstannanylium) methanediylidenediazanide
Stannane, tributylisothiocyanato-
tri-n-butylisocyanatotin
4-METHYLTHIAZOL-2-YLGUANIDINE HYDROCHLORIDE
1,2,4-Thiadiazole-3,5-diamine
guanidine
2-(Diaminomethyleneamino)-4-methylthiazole
[4-(Chloromethyl)-2-thiazolyl] Guanidine mono hydrochloride

Customs

[ HS Code ]: 2930909090

[ Summary ]:
2930909090. other organo-sulphur compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

Articles

[Mechanisms of the action of antihypoxic agents on central nervous system neurons].

Nerv. Sist. 27 , 8-16, (1988)

[The action of amtizol and gutimin on the respiratory metabolism of the neuron].

Farmakol. Toksikol. 54(3) , 22-4, (1991)

The effects of antihypoxants gutimine and amtisole on oxygen consumption by the intact nerve cell of the invertebrate and the activity of NADN-DH and SDH-dependent ways of oxidation in the cell were s...

[Ultrastructural features of heart insufficiency and its correction during the post-asphyxia period].

Biull. Eksp. Biol. Med. 109(1) , 72-4, (1990)

The ultrastructure of myocardium was studied in the experiments on rats during 24 hours after 6-min mechanical asphyxia with following clinical death. It has been established that the contractile card...