beta-Amanitin

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Names

[ CAS No. ]:
21150-22-1

[ Name ]:
beta-Amanitin

[Synonym ]:
MFCD00151212
8,20,23,24,27,30,33-octaoxo--dihydroxy-1-methylpropyl)-11-oxide
EINECS 244-244-8
B-amanitin from amanita phalloides
B-Amanitine
,12,17,18,19,20,21,22,23,23a-octadecahydro-29-sec-butyl-2,14-dihydroxy-21-(2,3

Chemical & Physical Properties

[ Molecular Formula ]:
C39H53N9O15S

[ Molecular Weight ]:
919.95400

[ Exact Mass ]:
919.33800

[ PSA ]:
394.30000

[ Index of Refraction ]:
1.695

MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
NJ8324000
CAS REGISTRY NUMBER :
21150-22-1
LAST UPDATED :
199612
DATA ITEMS CITED :
2
MOLECULAR FORMULA :
C39-H53-N9-O15-S
MOLECULAR WEIGHT :
920.07

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
400 ug/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
NEJMAG New England Journal of Medicine. (Massachusetts Medical Soc., 10 Shattuck St., Boston, MA 02115) V.198- 1928- Volume(issue)/page/year: 269,223,1963
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Unreported
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
400 ug/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951- Volume(issue)/page/year: 22,2142,1972

Safety Information

[ Symbol ]:

GHS06

[ Signal Word ]:
Danger

[ Hazard Statements ]:
H300-H310-H330

[ Precautionary Statements ]:
P260-P264-P280-P284-P302 + P350-P310

[ Hazard Codes ]:
T+

[ Risk Phrases ]:
R26/27/28

[ Safety Phrases ]:
S7;S28;S45;S36/S37/S39

[ RIDADR ]:
UN 3462 6.1/PG 1

[ RTECS ]:
NJ8324000

[ Hazard Class ]:
6.1(a)

Articles

[Determination of amanitatoxins by HPLC].

Chudoku. Kenkyu. 16(4) , 441-5, (2003)

High-performance liquid chromatographic (HPLC) assay has been developed for the simultaneous determination of alpha-amanitin, beta-amanitin and phalloidin in serum. Three toxins were extracted by refl...

Gas chromatography-mass spectrometry (GC-MS) and liquid chromatography-mass spectrometry (LC-MS) in toxicological analysis. Studies on the detection of clobenzorex and its metabolites within a systematic toxicological analysis procedure by GC-MS and by immunoassay and studies on the detection of alpha- and beta-amanitin in urine by atmospheric pressure ionization electrospray LC-MS.

J. Chromatogr. B. Biomed. Sci. Appl. 689(1) , 81-9, (1997)

GC-MS is the method of choice for toxicological analysis of toxicants volatile in GC while non-volatile and/or thermally labile toxicants need LC-MS for their determination. Studies are presented on t...

Validated electrospray liquid chromatographic-mass spectrometric assay for the determination of the mushroom toxins alpha- and beta-amanitin in urine after immunoaffinity extraction.

J. Chromatogr. B. Biomed. Sci. Appl. 748(1) , 125-35, (2000)

Specific detection of amanitins in body fluids is necessary for an early diagnosis of an intoxication with amanita mushrooms. In this paper, a liquid chromatographic-mass spectrometric assay after imm...


More Articles


Related Compounds

  • BETA-AMANITIN
  • beta-Estradiol 17-hemisuccinate
  • beta-D-Arabinopyranose (9CI)
  • Beta-D-glucopyranosyl oleanolate
  • Beta-D-allose
  • beta-D-Glucopyranuronic acid, 1-((acetyl(1,1'-biphenyl)-4-ylamino)oxy)-1-deoxy-
  • ethyl 2-(1-ethyl-3-methyl-1H-pyrazole-5-carboxamido)thiazole-4-carboxylate
  • N-(benzo[b]thiophen-5-yl)-1-ethyl-3-methyl-1H-pyrazole-5-carboxamide
  • 1-ethyl-N-(4-fluorobenzo[d]thiazol-2-yl)-3-methyl-1H-pyrazole-5-carboxamide
  • N-(7-chloro-4-methylbenzo[d]thiazol-2-yl)-1-ethyl-3-methyl-1H-pyrazole-5-carboxamide
  • N-(3-carbamoyl-5-phenylthiophen-2-yl)-1-ethyl-3-methyl-1H-pyrazole-5-carboxamide
  • 1-ethyl-N-(6-ethylbenzo[d]thiazol-2-yl)-3-methyl-N-(pyridin-2-ylmethyl)-1H-pyrazole-5-carboxamide
  • N-(4,7-dimethoxybenzo[d]thiazol-2-yl)-1-ethyl-3-methyl-N-(pyridin-2-ylmethyl)-1H-pyrazole-5-carboxamide
  • 1-ethyl-3-methyl-N-(4-(methylthio)phenyl)-1H-pyrazole-5-carboxamide
  • 1-ethyl-3-methyl-N-(2-(methylsulfonyl)phenyl)-1H-pyrazole-5-carboxamide
  • (E)-ethyl 2-((1-ethyl-3-methyl-1H-pyrazole-5-carbonyl)imino)-3,4-dimethyl-2,3-dihydrothiazole-5-carboxylate
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