2-Amino-1-[3-(trifluoromethyl)phenyl]ethanol

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Names

[ CAS No. ]:
21172-28-1

[ Name ]:
2-Amino-1-[3-(trifluoromethyl)phenyl]ethanol

[Synonym ]:
2-Amino-1-(3-(trifluoromethyl)phenyl)ethanol HCl
2-amino-1-<3-(trifluoromethyl)phenyl>ethanol
2-hydroxy-2-[(3-trifluoromethyl)phenyl]ethanamine
Benzenemethanol, α-(aminomethyl)-3-(trifluoromethyl)-
2-Amino-1-[3-(trifluoromethyl)phenyl]ethanol

Chemical & Physical Properties

[ Density]:
1.3±0.1 g/cm3

[ Boiling Point ]:
277.9±35.0 °C at 760 mmHg

[ Molecular Formula ]:
C9H10F3NO

[ Molecular Weight ]:
205.177

[ Flash Point ]:
121.9±25.9 °C

[ Exact Mass ]:
205.071442

[ PSA ]:
46.25000

[ LogP ]:
1.03

[ Vapour Pressure ]:
0.0±0.6 mmHg at 25°C

[ Index of Refraction ]:
1.493

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
DN7450000
CHEMICAL NAME :
Benzyl alcohol, alpha-aminomethyl-m-trifluoromethyl-
CAS REGISTRY NUMBER :
21172-28-1
LAST UPDATED :
199612
DATA ITEMS CITED :
1
MOLECULAR FORMULA :
C9-H10-F3-N-O
MOLECULAR WEIGHT :
205.20
WISWESSER LINE NOTATION :
FXFFR CYQM1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
226 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
17XKAB "International Symposium on Amphetamines and Related Compounds, Proceedings, Mario Negri Institute for Pharmacological Research, Milan, 1969," Costa, E., and S. Garattini, eds., New York, Raven Press, 1970 Volume(issue)/page/year: -,21,1970

Safety Information

[ HS Code ]:
2922199090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • 3-(Trifluoromethyl)benzaldehyde
  • Trimethylsilyl cyanide
  • 3-Bromobenzotrifluoride
  • POTASSIUM CYANIDE

DownStream

Customs

[ HS Code ]: 2922199090

[ Summary ]:
2922199090. other amino-alcohols, other than those containing more than one kind of oxygen function, their ethers and esters; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

Related Compounds

  • 2-amino-1-[3-(trifluoromethyl)phenyl]ethanol,hydrochloride
  • 2-amino-1-[3-(trifluoromethyl)phenyl]ethanone
  • 2-Amino-1-(3-trifluormethylphenyl)-1-phenylethanol
  • N,N-dimethyl-1-[3-(trifluoromethyl)phenyl]ethane-1,2-diamine
  • 2-AMINO-1-(3-METHOXY-PHENYL)-ETHANOL HCL
  • 2-Amino-1-[4-(trifluoromethyl)phenyl]ethanol
  • 3-(2,5-Dimethylfuran-3-carboxamido)cyclohexyl (4-fluorophenyl)carbamate
  • N-((1-ethylpiperidin-4-yl)methyl)-1,1,1-trifluoromethanamine
  • N-(2-(Aminomethyl)-4-cyclopropoxypyridin-3-YL)methanesulfonamide
  • 1-(2-Ethyl-2,8-diazaspiro[4.5]decan-8-yl)ethanone
  • 6-Ethyl-6-azaspiro[3.4]octane-2-carboxylic acid
  • 2-(Bromomethyl)-6-ethyl-6-azaspiro[3.4]octane
  • (6-Ethyl-6-azaspiro[3.4]octan-2-yl)methanol
  • (6-Ethyl-6-azaspiro[3.4]octan-2-yl)methanethiol
  • 6-Ethyl-6-azaspiro[3.4]octan-2-amine
  • 7-(Chloromethyl)-2-ethyl-2-azaspiro[4.4]nonane