2-Imidazolidinethione,4-methyl-

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Names

[ CAS No. ]:
2122-19-2

[ Name ]:
2-Imidazolidinethione,4-methyl-

[Synonym ]:
4-methyl-2-imidazolidinethione
4-Methyl-imidazolidin-2-thion
2-Imidazolidinethione,4-methyl
N,N'-(1,2-Propylene)thiourea
4-Methyl-2-thioxoimidazolidine
4-methyl-imidazolidine-2-thione
5-methyl-2-imidazolidinethione
4(5)-methyl-2-imidazolinethione
N,2-Propylene)-thiourea

Chemical & Physical Properties

[ Density]:
1.19g/cm3

[ Boiling Point ]:
157.3ºC at 760mmHg

[ Molecular Formula ]:
C4H8N2S

[ Molecular Weight ]:
116.18500

[ Flash Point ]:
49ºC

[ Exact Mass ]:
116.04100

[ PSA ]:
56.15000

[ LogP ]:
0.51020

[ Vapour Pressure ]:
2.77mmHg at 25°C

[ Index of Refraction ]:
1.591

MSDS

Click to get detail MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
NJ0400000
CHEMICAL NAME :
2-Imidazolidinethione, 4-methyl-
CAS REGISTRY NUMBER :
2122-19-2
LAST UPDATED :
198910
DATA ITEMS CITED :
5
MOLECULAR FORMULA :
C4-H8-N2-S
MOLECULAR WEIGHT :
116.20
WISWESSER LINE NOTATION :
T5MYMTJ BUS D1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
50 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
EJMCA5 European Journal of Medicinal Chemistry--Chimie Therapeutique. (Editions Scientifiques Elsevier, 29 rue Buffon, F-75005, Paris, France) V.9- 1974- Volume(issue)/page/year: 17,235,1982 ** REPRODUCTIVE DATA **
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
DOSE :
75 mg/kg
SEX/DURATION :
female 13 day(s) after conception
TOXIC EFFECTS :
Reproductive - Specific Developmental Abnormalities - Central Nervous System Reproductive - Specific Developmental Abnormalities - musculoskeletal system
REFERENCE :
MVMZA8 Monatshefte fuer Veterinaermedizin. (VEB Gustav Fischer Verlag, Postfach 176, Jena DDR-6900, Ger. Dem. Rep.) V.1- 1946- Volume(issue)/page/year: 33,137,1978
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
DOSE :
100 mg/kg
SEX/DURATION :
female 13 day(s) after conception
TOXIC EFFECTS :
Reproductive - Effects on Embryo or Fetus - fetotoxicity (except death, e.g., stunted fetus) Reproductive - Specific Developmental Abnormalities - craniofacial (including nose and tongue)
REFERENCE :
MVMZA8 Monatshefte fuer Veterinaermedizin. (VEB Gustav Fischer Verlag, Postfach 176, Jena DDR-6900, Ger. Dem. Rep.) V.1- 1946- Volume(issue)/page/year: 33,137,1978
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
DOSE :
2400 mg/kg
SEX/DURATION :
female 13 day(s) after conception
TOXIC EFFECTS :
Reproductive - Specific Developmental Abnormalities - eye/ear
REFERENCE :
MVMZA8 Monatshefte fuer Veterinaermedizin. (VEB Gustav Fischer Verlag, Postfach 176, Jena DDR-6900, Ger. Dem. Rep.) V.1- 1946- Volume(issue)/page/year: 33,137,1978
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
DOSE :
450 mg/kg
SEX/DURATION :
female 6-15 day(s) after conception
TOXIC EFFECTS :
Reproductive - Specific Developmental Abnormalities - other developmental abnormalities
REFERENCE :
BSIBAC Bolletino della Societe Italiana di Biologia Sperimentale. (Casa Editrice Idelson, Via A. de Gasperi, 55, 80133 Naples, Italy) V.2- 1927- Volume(issue)/page/year: 61,271,1985

Safety Information

[ Symbol ]:

GHS07, GHS08

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H302-H361-H412

[ Precautionary Statements ]:
P273-P281

[ Personal Protective Equipment ]:
Eyeshields;full-face particle respirator type N100 (US);Gloves;respirator cartridge type N100 (US);type P1 (EN143) respirator filter;type P3 (EN 143) respirator cartridges

[ Hazard Codes ]:
Xn: Harmful;

[ Risk Phrases ]:
22-52/53-63

[ Safety Phrases ]:
36/37-46-61

[ RIDADR ]:
NONH for all modes of transport

[ RTECS ]:
NJ0400000

[ HS Code ]:
2933990090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • 5-METHYL-2-THIOXOIMIDAZOLIDIN-4-ONE
  • Carbon disulphide
  • 1,2-Diaminopropane

DownStream

  • 3,6-dimethyl-N-(2,4,6-trimethylphenyl)-5,6-dihydroimidazo[2,1-b][1,3]thiazole-2-carboxamide
  • 4-METHYL-2-(METHYLTHIO)-4,5-DIHYDRO-1H-IMIDAZOLEHYDROIODIDE

Customs

[ HS Code ]: 2933990090

[ Summary ]:
2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Related Compounds

  • 2-IMIDAZOLIDINETHIONE,4-METHYL-4-PHENYL
  • 2-Imidazolidinethione,4,5-dihydroxy-1-methyl-
  • 2-(4-methyl-6-phenylpyrimidin-2-yl)sulfanylacetic acid
  • [2-[4-methyl-2-(2-methylpropanoyloxy)phenyl]oxiran-2-yl]methyl benzoate
  • 2-(4-methyl-1,3-thiazol-2-yl)-3a,4,5,6,7,7a-hexahydro-octahydro-1H-4,7-epoxyisoindole-1,3-dione
  • 2-(4-methyl-2-nitro-phenoxy)-ethanol
  • tert-butyl N-{5-[(fluorosulfonyl)methyl]pyrimidin-2-yl}carbamate
  • 4-((Cyclohexylamino)methyl)benzoic acid hydrochloride
  • 1-[(2,4-Dichlorophenyl)methyl]-N-(1,1-dimethylethyl)-2-methyl-1H-indole-3-methanamine
  • 4-[2-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)-3-methoxypropanamido]-3-methoxybutanoic acid
  • 2-Methoxy-6-(pyrazol-1-yl)-benzonitrile
  • 1H-3-Benzazepin-7-ol, 8-chloro-2,3,4,5-tetrahydro-5-(3-iodophenyl)-3-methyl-, (S)-
  • (4-Methyl-tetrahydro-furan-2-yl)-methanol
  • N-(1-cyanocyclopentyl)-2-[4-(4-fluorobenzenesulfonyl)-1,4-diazepan-1-yl]acetamide
  • 5-[3-(nitromethyl)phenyl]-1H-1,2,3,4-tetrazole
  • 4,5,6,7-Tetrahydrobenzo[d]isoxazole-3-carbaldehyde