PD184352 (CI-1040)

Suppliers

Names

[ Name ]:
PD184352 (CI-1040)

[Synonym ]:
Benzamide, 2-[(2-chloro-4-iodophenyl)amino]-N-(cyclopropylmethoxy)-3,4-difluoro-
CI-1040
2-[(2-Chloro-4-iodophenyl)amino]-N-(cyclopropylmethoxy)-3,4-difluorobenzamide
2-(2-Chloro-4-iodophenylamino)-N-cyclopropylmethoxy-3,4-difluorobenzamide CI-1040
2-((2-Chloro-4-iodophenyl)amino)-N-(cyclopropylmethoxy)-3,4-difluorobenzamide
2-(2-chloro-4-iodophenylamino)-N-(cyclopropylmethoxy)-3,4-difluorobenzamide

Chemical & Physical Properties

[ Density]:
1.7±0.1 g/cm3

[ Melting Point ]:
166-169ºC

[ Molecular Formula ]:
C₁₇H₁₄ClF₂IN₂O₂

[ Molecular Weight ]:
478.659

[ Exact Mass ]:
477.975647

[ PSA ]:
50.36000

[ LogP ]:
8.01

[ Index of Refraction ]:
1.656

[ Storage condition ]:
-20°C Freezer

[ Water Solubility ]:
DMSO: ≥30mg/mL

Safety Information

[ Symbol ]:

GHS09

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H400

[ Precautionary Statements ]:
P273

[ Hazard Codes ]:
N

[ Risk Phrases ]:
50/53

[ Safety Phrases ]:
60-61

[ RIDADR ]:
UN 3077 9 / PGIII

[ HS Code ]:
2924299090

Customs

[ HS Code ]: 2924299090

[ Summary ]:
2924299090. other cyclic amides (including cyclic carbamates) and their derivatives; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

Articles

Multitarget effects of quercetin in leukemia.

Cancer Prev. Res. (Phila.) 7(12) , 1240-50, (2014)

This study proposes to investigate quercetin antitumor efficacy in vitro and in vivo, using the P39 cell line as a model. The experimental design comprised leukemic cells or xenografts of P39 cells, t...

BAFF activation of the ERK5 MAP kinase pathway regulates B cell survival.

J. Exp. Med. 212 , 883-92, (2015)

B cell activating factor (BAFF) stimulation of the BAFF receptor (BAFF-R) is essential for the homeostatic survival of mature B cells. Earlier in vitro experiments with inhibitors that block MEK 1 and...

Mechanisms of tolvaptan-induced toxicity in HepG2 cells.

Biochem. Pharmacol. 95 , 324-36, (2015)

Tolvaptan, a vasopressin receptor 2 antagonist used to treat hyponatremia, has recently been reported to be associated with an increased risk of liver injury. In this study, we explored the underlying...

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