2'-O-Methyladenosine

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Names

[ CAS No. ]:
2140-79-6

[ Name ]:
2'-O-Methyladenosine

[Synonym ]:
UNII-02YX82IHZ5
2'-O-Methyl adenosine
2'-methyl-adenosine
2'-O-methylAdo
2′-O-Methyladenosine
(2R,3R,4R,5R)-5-(6-aminopurin-9-yl)-2-(hydroxymethyl)-4-methoxyoxolan-3-ol
2'-methoxyadenosine
2'-OMeAdenosine
MFCD00056002
Adenosine, 2'-O-methyl-
2'-O-Methyladenosine
2'-O-Methyl-D-adenosine
(2R,3R,4R,5R)-5-(6-Amino-9H-purin-9-yl)-2-(hydroxymethyl)-4-methoxytetrahydrofuran-3-ol
Adenosine,2'-O-methyl

Chemical & Physical Properties

[ Density]:
1.8±0.1 g/cm3

[ Boiling Point ]:
623.8±65.0 °C at 760 mmHg

[ Melting Point ]:
200-202ºC

[ Molecular Formula ]:
C11H15N5O4

[ Molecular Weight ]:
281.268

[ Flash Point ]:
331.0±34.3 °C

[ Exact Mass ]:
281.112396

[ PSA ]:
128.54000

[ LogP ]:
-0.15

[ Vapour Pressure ]:
0.0±1.9 mmHg at 25°C

[ Index of Refraction ]:
1.795

[ Storage condition ]:
−20°C

MSDS

Click to get detail MSDS

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ Hazard Codes ]:
Xi

[ Risk Phrases ]:
R36/37/38

[ Safety Phrases ]:
26-36

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

[ HS Code ]:
2934999090

Precursor & DownStream

Precursor

  • Trimethylsulfonium hydroxide
  • Adenosine
  • methyl iodide
  • diazomethane
  • trimethylselenonium hydroxyde
  • Methyl p-toluenesulfonate
  • Adenosine, 3'-O-methyl-(7CI,8CI,9CI)
  • N,N,N-Trimethylanilinium hydroxide
  • Trimethyl phosphate

DownStream

  • 2'-(o-methyl)-inosine
  • N6,2′-O-Dimethyladenosine
  • 2',3'-DIMETHOXYADENOSINE
  • (2R,3R,4R,5R)-5-(6-amino-1-methyl-2H-purin-9-yl)-2-(hydroxymethyl)-4-m ethoxy-oxolan-3-ol
  • N,N-Dimethyl-2′-O-methyladenosine

Customs

[ HS Code ]: 2934999090

[ Summary ]:
2934999090. other heterocyclic compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Articles

Increased excretion of modified adenine nucleosides by children with adenosine deaminase deficiency.

Pediatr. Res. 16(5) , 362-9, (1982)

We have identified seven adenine nucleosides in urines of untreated adenosine deaminase (ADA) deficient patients, four of which (adenosine, 2'-deoxyadenosine, 1-methyladenosine and N6-methyladenosine)...

Stabilizing effects of the RNA 2'-substituent: crystal structure of an oligodeoxynucleotide duplex containing 2'-O-methylated adenosines.

Chem. Biol. 1(1) , 39-45, (1994)

The stability of hybrids of 2'-O-methyl-ribonucleotides with complementary RNA is considerably higher than that of the corresponding DNA.RNA duplexes. The 2'-O-modified ribonucleotides are thus an att...

Effect of PGE2 and of agents that raise cAMP levels on macrophage activation induced by IFN-gamma and TNF-alpha.

J. Leukoc. Biol. 58(2) , 217-24, (1995)

The effect of prostaglandin (PG) E2 on macrophage activation by interferon-gamma (IFN-gamma) and tumor necrosis factor-alpha (TNF-alpha) was evaluated. Murine macrophages infected with Leishmania enri...


More Articles

Related Compounds

  • 2'-O-Methyladenosine
  • 2'-O-METHYLADENOSINE
  • N-Cyclohexyl-2'-O-methyladenosine
  • 2'-O-methyladenosine 5'-monophosphate
  • N6-Benzoyl-5'-O-DMT-2'-O-methyladenosine
  • 2-amino-n2-isobutyryl-2'-o-methyladenosine
  • tert-butyl N-{4-bromo-1H-pyrrolo[2,3-c]pyridin-7-yl}carbamate
  • Chloromethyl 2-{[(tert-butoxy)carbonyl]amino}-4-(dimethylamino)butanoate
  • tert-butyl N-(5-bromo-1H-indazol-3-yl)carbamate
  • tert-butyl N-{7-bromoimidazo[1,2-a]pyridin-3-yl}carbamate
  • 3-methyl-1H,1aH,6H,6aH-cyclopropa[a]inden-1-amine
  • 6-(Thiophen-2-yl)pyridine-2-sulfonyl fluoride
  • tert-butyl N-(6-bromo-2,3-dihydro-1H-inden-5-yl)carbamate
  • 5-(Thiophen-3-yl)-3-(trifluoromethyl)pyridin-2-ol
  • rac-benzyl N-[(1R,2S)-2-bromocyclohexyl]carbamate
  • 1-[1-(1-Amino-3,3,4,4,4-pentafluorobutan-2-yl)pyrrolidin-3-yl]ethan-1-ol
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