2'-O-Methyladenosine

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Names

[ Name ]:
2'-O-Methyladenosine

[Synonym ]:
UNII-02YX82IHZ5
2'-O-Methyl adenosine
2'-methyl-adenosine
2'-O-methylAdo
2′-O-Methyladenosine
(2R,3R,4R,5R)-5-(6-aminopurin-9-yl)-2-(hydroxymethyl)-4-methoxyoxolan-3-ol
2'-methoxyadenosine
2'-OMeAdenosine
MFCD00056002
Adenosine, 2'-O-methyl-
2'-O-Methyladenosine
2'-O-Methyl-D-adenosine
(2R,3R,4R,5R)-5-(6-Amino-9H-purin-9-yl)-2-(hydroxymethyl)-4-methoxytetrahydrofuran-3-ol
Adenosine,2'-O-methyl

Chemical & Physical Properties

[ Density]:
1.8±0.1 g/cm3

[ Boiling Point ]:
623.8±65.0 °C at 760 mmHg

[ Melting Point ]:
200-202ºC

[ Molecular Formula ]:
C₁₁H₁₅N₅O₄

[ Molecular Weight ]:
281.268

[ Flash Point ]:
331.0±34.3 °C

[ Exact Mass ]:
281.112396

[ PSA ]:
128.54000

[ LogP ]:
-0.15

[ Vapour Pressure ]:
0.0±1.9 mmHg at 25°C

[ Index of Refraction ]:
1.795

[ Storage condition ]:
−20°C

MSDS

Click to get detail MSDS

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ Hazard Codes ]:
Xi

[ Risk Phrases ]:
R36/37/38

[ Safety Phrases ]:
26-36

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

[ HS Code ]:
2934999090

Precursor & DownStream

Precursor

Trimethylsulfonium hydroxide
Adenosine
methyl iodide
diazomethane
trimethylselenonium hydroxyde
Methyl p-toluenesulfonate
Adenosine, 3'-O-methyl-(7CI,8CI,9CI)
N,N,N-Trimethylanilinium hydroxide
Trimethyl phosphate

DownStream

2'-(o-methyl)-inosine
N6,2′-O-Dimethyladenosine
2',3'-DIMETHOXYADENOSINE
(2R,3R,4R,5R)-5-(6-amino-1-methyl-2H-purin-9-yl)-2-(hydroxymethyl)-4-m ethoxy-oxolan-3-ol
N,N-Dimethyl-2′-O-methyladenosine

Customs

[ HS Code ]: 2934999090

[ Summary ]:
2934999090. other heterocyclic compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Articles

Increased excretion of modified adenine nucleosides by children with adenosine deaminase deficiency.

Pediatr. Res. 16(5) , 362-9, (1982)

We have identified seven adenine nucleosides in urines of untreated adenosine deaminase (ADA) deficient patients, four of which (adenosine, 2'-deoxyadenosine, 1-methyladenosine and N6-methyladenosine)...

Stabilizing effects of the RNA 2'-substituent: crystal structure of an oligodeoxynucleotide duplex containing 2'-O-methylated adenosines.

Chem. Biol. 1(1) , 39-45, (1994)

The stability of hybrids of 2'-O-methyl-ribonucleotides with complementary RNA is considerably higher than that of the corresponding DNA.RNA duplexes. The 2'-O-modified ribonucleotides are thus an att...

Effect of PGE2 and of agents that raise cAMP levels on macrophage activation induced by IFN-gamma and TNF-alpha.

J. Leukoc. Biol. 58(2) , 217-24, (1995)

The effect of prostaglandin (PG) E2 on macrophage activation by interferon-gamma (IFN-gamma) and tumor necrosis factor-alpha (TNF-alpha) was evaluated. Murine macrophages infected with Leishmania enri...

2'-O-Methyladenosine
2'-O-METHYLADENOSINE
N-Cyclohexyl-2'-O-methyladenosine
2'-O-methyladenosine 5'-monophosphate
N6-Benzoyl-5'-O-DMT-2'-O-methyladenosine
2-amino-n2-isobutyryl-2'-o-methyladenosine
(3-(Aminomethyl)piperidin-1-yl)(2,4-dimethylthiazol-5-yl)methanone
2-(Benzenesulfonyl)-5-bromobenzaldehyde
2-(Difluoromethyl)-4-methyl-3-nitropyridine-5-carboxamide
2-(Difluoromethyl)-4-fluoropyridine-3-carboxamide
2-(Difluoromethyl)-3-hydroxy-5-nitro-4-(trifluoromethyl)pyridine
2-(Difluoromethyl)-5-fluoro-3-nitro-4-(trifluoromethoxy)pyridine
4-Bromo-2-chloro-5-methoxypyrimidine
2-(Difluoromethyl)-5-iodo-4-nitropyridine-3-methanol
2-(Difluoromethyl)-5-methoxy-3-methylpyridine-4-carbonyl chloride
2-(Difluoromethyl)-3,5-dimethoxypyridine-4-carbonyl chloride

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