Phthalimide, N-benzyl-

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Names

[ Name ]:
Phthalimide, N-benzyl-

[Synonym ]:
2-Benzylisoindoline-1,3-dione
1H-Isoindole-1,3(2H)-dione, 2-(phenylmethyl)-
2-benzylisoindole-1,3-dione
N-Benzylphthalimide
EINECS 218-395-5
2-benzyl-1H-isoindol-1,3(2H)-dione
2-Benzyl-1,3-isoindolinedione
2-(phenylmethyl)isoindole-1,3-dione
2-(phenylmethyl)-1H-isoindole-1,3(2H)-dione
2-(benzyl)isoindoline-1,3-quinone
MFCD00023077
N-BENZYLPHTALIMIDE
BENZYLPHTHALIMIDE
2-Benzyl-1H-isoindole-1,3(2H)-dione
Phthalimide, N-benzyl-
1H-Isoindole-1,3(2H)-dione,2-(phenylMethyl)

Chemical & Physical Properties

[ Density]:
1.3±0.1 g/cm3

[ Boiling Point ]:
393.0±21.0 °C at 760 mmHg

[ Melting Point ]:
114-116 °C(lit.)

[ Molecular Formula ]:
C₁₅H₁₁NO₂

[ Molecular Weight ]:
237.253

[ Flash Point ]:
179.8±14.4 °C

[ Exact Mass ]:
237.078979

[ PSA ]:
37.38000

[ LogP ]:
3.33

[ Vapour Pressure ]:
0.0±0.9 mmHg at 25°C

[ Index of Refraction ]:
1.660

MSDS

Click to get detail MSDS

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H302

[ Hazard Codes ]:
Xn

[ Risk Phrases ]:
R20/21/22

[ Safety Phrases ]:
26-36

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

[ HS Code ]:
2925190090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

Benzyl alcohol
N-methylsulfonylphthalimide
Benzylamine
Benzyl chloride
Methyl 2-iodobenzoate
Isocyanatomethylbenzene
Methyl 2-bromobenzoate
carbon monoxide

DownStream

Benzylamine
Phthalic acid
N-Allylbenzylamine
1,2-Benzenedicarboxamide,N1,N2-bis(phenylmethyl)-
N-Methylbenzylamine
Dibenzylamine
2-BENZYLISOINDOLINE
2-benzyl-2H-isoindole
2-[(2-nitrophenyl)methyl]isoindole-1,3-dione
2-(4-nitrobenzyl)-1H-isoindole-1,3(2H)-dione

Customs

[ HS Code ]: 2925190090

[ Summary ]:
2925190090 other imides and their derivatives; salts thereof VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:30.0%

Articles

Novel and versatile methodology for synthesis of cyclic imides and evaluation of their cytotoxic, DNA binding, apoptotic inducing activities and molecular modeling study.

Eur. J. Med. Chem. 42 , 614-26, (2007)

Versatile method has been developed for synthesis of N-substituted imides. Thus, acid anhydrides, imides and dicarboxylic acids were successfully subjected to dehydrative cyclization with substituted ...

Inhibition of monoamine oxidase by C5-substituted phthalimide analogues.

Bioorg. Med. Chem. 19 , 4829-40, (2011)

Literature reports that isatin as well as C5- and C6-substituted isatin analogues are reversible inhibitors of human monoamine oxidase (MAO) A and B. In general, C5- and C6-substitution of isatin lead...

N-benzylphthalimide. Warzecha K-D, et al.

Acta Crystallogr. Sect. E Struct. Rep. Online 62(6) , 2367-68, (2006)

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Phthalimide, N-anilinotetraiodo-
3-(N-benzyl-N-ethylamino)-5-methylphenol
3-((N-benzyl)acetamido)quinuclidine
ethyl N-benzyl-N-((ethoxycarbonyl)methyl)succinamate
pentacarbonyl(N-benzyl-2-azacyclotridecylidene)chromium(0)
Azetidine-1-carboximidamide
4'-Ethylamino-2-methoxy-3'-nitroacetanilide
(R)-2-Amino-N-methyl-2-phenylacetamide
Ethyl 2-(4-aminothiophen-3-yl)acetate
6-Methyl-3-(2-propynyloxy)-pyridine
5,5-Dimethyl-5,6-dihydro-4H-pyrrolo[1,2-b]pyrazole-3-carboxylic acid
2,2-Dichloro-1-(3-methylphenyl)cyclopropane-1-carboxylic acid
2-Phenyl-1,3-dioxane-4-carboxylic acid
1-(2,5-Dichlorophenyl)ethane-1,2-diamine
2-Butyl-1,3,2-dioxaphospholane2-oxide