ortho-hydroxy atorvastatin

Names

[ CAS No. ]:
214217-86-4

[ Name ]:
ortho-hydroxy atorvastatin

[Synonym ]:
o-Hydroxyatorvastatin Disodium Salt
o-Hydroxyatorvastatin
ortho-hydroxyatorvastatin
2-hydroxy-atorvastatin
2-Hydroxy Atorvastatin Dihydrate Monosodium Salt

Chemical & Physical Properties

[ Melting Point ]:
132-134ºC

[ Molecular Formula ]:
C33H38FN2NaO8

[ Molecular Weight ]:
632.65200

[ Exact Mass ]:
632.25100

[ PSA ]:
153.31000

[ LogP ]:
4.62890

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • 2-(Benzyloxy)aniline
  • benzyl 2-nitrophenyl ether
  • N-2-BENZYLOXYPHENYL ISOBUTYRYLACETAMIDE
  • 2-benzylidene-N-(2-(benzyloxy)phenyl)-4-methyl-3-oxopentanamide
  • 2-[2-(4-Fluorophenyl)-2-oxo-1-phenyl-ethyl]-4-methyl-3-oxo-pentanoic Acid, (2-Benzyloxy-phenyl)-amide
  • (6-{2-[2-(4-Fluoro-phenyl)-4-(2-hydroxy-phenylcarbamoyl)-5-isopropyl-3-phenyl-pyrrol-1-yl]-ethyl}-2,2-dimethyl-[1,3]-dioxane-4-yl)-acetic Acid, tert-Butyl Ester

DownStream

Related Compounds

  • Ortho-hydroxy atorvastatin lactone-d5
  • 4-hydroxy Atorvastatin lactone
  • (6-{2-[2-(4-Fluoro-phenyl)-4-(2-hydroxy-phenylcarbamoyl)-5-isopropyl-3-phenyl-pyrrol-1-yl]-ethyl}-2,2-dimethyl-[1,3]-dioxane-4-yl)-acetic Acid, tert-Butyl Ester
  • p-Hydroxy Atorvastatin Calcium Salt
  • 4-Hydroxy Atorvastatin-d5 calcium
  • o-Hydroxy Atorvastatin D5 Calcium Salt
  • 4-ethyl-5-fluoro-6-{4-[6-(1-methyl-1H-pyrazol-4-yl)pyrazin-2-yl]piperazin-1-yl}pyrimidine
  • 2-(1-methyl-1H-pyrazol-4-yl)-6-{4-[6-(trifluoromethyl)pyridin-2-yl]piperazin-1-yl}pyrazine
  • 2-methyl-4-{4-[(5-methyl-1,2-oxazol-3-yl)methyl]piperazin-1-yl}-6-(1H-pyrazol-1-yl)pyrimidine
  • 2-{4-[(2-methyl-1,3-oxazol-4-yl)methyl]piperazin-1-yl}-6-(1-methyl-1H-pyrazol-4-yl)pyrazine
  • 2-(4-{Pyrazolo[1,5-a]pyrimidin-5-yloxy}piperidin-1-yl)-5-(trifluoromethyl)pyridine
  • 2-(4-{Pyrazolo[1,5-a]pyrimidin-5-yloxy}piperidin-1-yl)-3-(trifluoromethyl)pyridine
  • 3-chloro-2-[(1-{1-methyl-1H-pyrazolo[3,4-d]pyrimidin-4-yl}piperidin-3-yl)methoxy]pyridine
  • 3-Methyl-6-[(1-{pyrido[2,3-d]pyrimidin-4-yl}piperidin-4-yl)methoxy]pyridazine
  • 1-{[3-(Propan-2-yl)-1,2,4-oxadiazol-5-yl]methyl}-4-{pyrazolo[1,5-a]pyrimidin-5-yloxy}piperidine
  • 3-Chloro-2-[(1-{5-methyl-[1,2,4]triazolo[1,5-a]pyrimidin-7-yl}piperidin-3-yl)methoxy]pyridine
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