(S)-tert-Butyl 4,4-difluoro-2-(hydroxymethyl)-pyrrolidine-1-carboxylate

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Names

[ CAS No. ]:
215918-21-1

[ Name ]:
(S)-tert-Butyl 4,4-difluoro-2-(hydroxymethyl)-pyrrolidine-1-carboxylate

[Synonym ]:
tert-butyl (2S)-4,4-difluoro-2-(hydroxymethyl)pyrrolidine-1-carboxylate

Chemical & Physical Properties

[ Density]:
1.21g/cm3

[ Boiling Point ]:
293.4ºC at 760 mmHg

[ Molecular Formula ]:
C10H17F2NO3

[ Molecular Weight ]:
237.24400

[ Flash Point ]:
131.3ºC

[ Exact Mass ]:
237.11800

[ PSA ]:
49.77000

[ LogP ]:
1.56130

[ Vapour Pressure ]:
0.000183mmHg at 25°C

[ Index of Refraction ]:
1.465

Safety Information

[ HS Code ]:
2933990090

Synthetic Route

Precursor & DownStream

Precursor

  • N-t-BOC-4,4-Difluoro-L-proline methyl ester
  • N-t-BOC-4,4-Difluoro-L-Proline
  • Boc-4-oxo-Pro-OMe
  • Di-tert-butyl dicarbonate
  • H-Hyp-OMe hydrochloride
  • Boc-Hyp-OMe

DownStream

Customs

[ HS Code ]: 2933990090

[ Summary ]:
2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%


Related Compounds

  • N-cyclobutyl-octahydro-1H-2-benzopyran-6-amine
  • [3-(Benzyloxy)-2,2-difluoropropyl](propyl)amine
  • Benzyl(4-methoxy-3,3-dimethylbutyl)amine
  • N-(4-methoxy-2,2-dimethylbutyl)thiophen-3-amine
  • {2-[1-(2-Methoxyethyl)cyclobutyl]ethyl}(3-methoxypropyl)amine
  • N-cyclopropyl-3-[2-(dimethylamino)ethyl]-3H-[1,2,3]triazolo[4,5-d]pyrimidin-7-amine
  • N-cyclopropyl-3-pentyl-3H-[1,2,3]triazolo[4,5-d]pyrimidin-7-amine
  • 9-Methyl-5-(1,3-thiazol-2-yl)-1-oxa-4-azaspiro[5.6]dodecane
  • 1,3,3-Trimethyl-10-(1,3-thiazol-2-yl)-6-oxa-9-azaspiro[4.5]decane
  • 2,2-Diethyl-3-(4-fluorophenyl)morpholine
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