(S)-tert-Butyl 4,4-difluoro-2-(hydroxymethyl)-pyrrolidine-1-carboxylate

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Names

[ CAS No. ]:
215918-21-1

[ Name ]:
(S)-tert-Butyl 4,4-difluoro-2-(hydroxymethyl)-pyrrolidine-1-carboxylate

[Synonym ]:
tert-butyl (2S)-4,4-difluoro-2-(hydroxymethyl)pyrrolidine-1-carboxylate

Chemical & Physical Properties

[ Density]:
1.21g/cm3

[ Boiling Point ]:
293.4ºC at 760 mmHg

[ Molecular Formula ]:
C10H17F2NO3

[ Molecular Weight ]:
237.24400

[ Flash Point ]:
131.3ºC

[ Exact Mass ]:
237.11800

[ PSA ]:
49.77000

[ LogP ]:
1.56130

[ Vapour Pressure ]:
0.000183mmHg at 25°C

[ Index of Refraction ]:
1.465

Safety Information

[ HS Code ]:
2933990090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • N-t-BOC-4,4-Difluoro-L-proline methyl ester
  • N-t-BOC-4,4-Difluoro-L-Proline
  • Boc-4-oxo-Pro-OMe
  • Di-tert-butyl dicarbonate
  • H-Hyp-OMe hydrochloride
  • Boc-Hyp-OMe

DownStream

Customs

[ HS Code ]: 2933990090

[ Summary ]:
2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Related Compounds

  • 7-Phenylmethoxy-1H-indole-3-sulfonyl chloride
  • 3-[(2-Methylpropan-2-yl)oxycarbonylamino]-5,6,7,8-tetrahydronaphthalene-2-carboxylic acid
  • 1-[(2-Methylpropan-2-yl)oxycarbonyl]-3-[2-[(2-methylpropan-2-yl)oxy]-2-oxoethyl]azetidine-3-carboxylic acid
  • Methyl 5-fluorosulfonyl-3-methylpyridine-2-carboxylate
  • 4-(Phenylsulfonimidoyl)butan-1-amine
  • 2-Amino-3-(2-bromopyridine-4-sulfonamido)propanoic acid
  • 6-Hydroxy-1-methylazepan-2-one
  • (2S,4S)-4-(Cyclobutylmethyl)-1-(9H-fluoren-9-ylmethoxycarbonyl)pyrrolidine-2-carboxylic acid
  • (S)-Cyclopentyl(dimethylphosphoryl)methanamine
  • 3-(2-Bromo-5-chlorosulfonyl-4-methoxyphenyl)propanoic acid
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