(S)-tert-Butyl 4,4-difluoro-2-(hydroxymethyl)-pyrrolidine-1-carboxylate

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Names

[ CAS No. ]:
215918-21-1

[ Name ]:
(S)-tert-Butyl 4,4-difluoro-2-(hydroxymethyl)-pyrrolidine-1-carboxylate

[Synonym ]:
tert-butyl (2S)-4,4-difluoro-2-(hydroxymethyl)pyrrolidine-1-carboxylate

Chemical & Physical Properties

[ Density]:
1.21g/cm3

[ Boiling Point ]:
293.4ºC at 760 mmHg

[ Molecular Formula ]:
C10H17F2NO3

[ Molecular Weight ]:
237.24400

[ Flash Point ]:
131.3ºC

[ Exact Mass ]:
237.11800

[ PSA ]:
49.77000

[ LogP ]:
1.56130

[ Vapour Pressure ]:
0.000183mmHg at 25°C

[ Index of Refraction ]:
1.465

Safety Information

[ HS Code ]:
2933990090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • N-t-BOC-4,4-Difluoro-L-proline methyl ester
  • N-t-BOC-4,4-Difluoro-L-Proline
  • Boc-4-oxo-Pro-OMe
  • Di-tert-butyl dicarbonate
  • H-Hyp-OMe hydrochloride
  • Boc-Hyp-OMe

DownStream

Customs

[ HS Code ]: 2933990090

[ Summary ]:
2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Related Compounds

  • 4-(Difluoromethyl)-6-iodo-5-(trifluoromethoxy)nicotinaldehyde
  • 4-(Difluoromethyl)-2-iodo-5-methylnicotinic acid
  • 1-(2-Ethoxybenzo[d]oxazol-4-yl)ethanone
  • 4-(Aminomethyl)-3-chloro-6-(difluoromethyl)picolinaldehyde
  • 2-(4,5-Dibromo-1H-indol-3-yl)acetic acid
  • 4,5-Dichloro-2-(difluoromethyl)nicotinamide
  • 4-(Difluoromethyl)-2-iodo-1-methylbenzene
  • 2-(4-Aminobenzo[d]oxazol-2-yl)-2-hydroxyacetic acid
  • 4,5-Difluoro-2-nitrobenzodifluoride
  • (5-(Difluoromethyl)-3-fluoro-2-iodopyridin-4-yl)methanamine
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