6-AZAURIDINE 2',3',5'-TRIACETATE
Suppliers
Names
[ CAS No. ]:
2169-64-4
[ Name ]:
6-AZAURIDINE 2',3',5'-TRIACETATE
[Synonym ]:
EINECS 218-515-6
6-AZURD-TA
6-azauridine-2',3',5'-tri-O-acetate
triacetyl-6-azauridine
ta-azur
cb304
2',3',5'-TRI-O-ACETYL-6-AZAURIDINE
AZARIBINE
2',3',5'-triacetyl-6-azauridine
Chemical & Physical Properties
[ Density]:
1.6g/cm3
[ Melting Point ]:
99-101ºC(lit.)
[ Molecular Formula ]:
C14H17N3O9
[ Molecular Weight ]:
371.29900
[ Exact Mass ]:
371.09600
[ PSA ]:
155.88000
[ Index of Refraction ]:
1.621
MSDS
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- XY8577000
- CHEMICAL NAME :
- as-Triazine-3,5-(2H,4H)-dione, 2-(2',3',5'-triacetyl-beta-D-ribofuranosyl)-
- CAS REGISTRY NUMBER :
- 2169-64-4
- LAST UPDATED :
- 199612
- DATA ITEMS CITED :
- 5
- MOLECULAR FORMULA :
- C14-H17-N3-O9
- MOLECULAR WEIGHT :
- 371.34
- WISWESSER LINE NOTATION :
- T6NNVMVJ B- CT5OTJ BOV1 DOV1 E1OV1
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Human
- DOSE/DURATION :
- 5670 mg/kg/6W
- TOXIC EFFECTS :
- Behavioral - somnolence (general depressed activity) Behavioral - convulsions or effect on seizure threshold Blood - changes in cell count (unspecified)
- REFERENCE :
- AJOGAH American Journal of Obstetrics and Gynecology. (C.V. Mosby Co., 11830 Westline Industrial Dr., St. Louis, MO 63146) V.1- 1920- Volume(issue)/page/year: 108,272,1970
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 12 gm/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- TXAPA9 Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1959- Volume(issue)/page/year: 17,511,1970
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 7800 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- TXAPA9 Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1959- Volume(issue)/page/year: 17,511,1970 ** OTHER MULTIPLE DOSE TOXICITY DATA **
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 321 gm/kg/15W-I
- TOXIC EFFECTS :
- Gastrointestinal - hypermotility, diarrhea Blood - changes in erythrocyte (RBC) count Related to Chronic Data - death
- REFERENCE :
- TXAPA9 Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1959- Volume(issue)/page/year: 17,511,1970
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Mammal - pig
- DOSE/DURATION :
- 30 gm/kg/14W-I
- TOXIC EFFECTS :
- Blood - changes in erythrocyte (RBC) count
- REFERENCE :
- TXAPA9 Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1959- Volume(issue)/page/year: 17,511,1970
Safety Information
[ Safety Phrases ]:
S22-S24/25
[ WGK Germany ]:
2
[ RTECS ]:
XY8577000