n-propylmaleimide

Names

[ Name ]:
n-propylmaleimide

[Synonym ]:
N-PROPYLAMALEIMIDE
N-propyl maleimide
N-Propylmaleinimide
1H-Pyrrole-2,5-dione,1-propyl
EINECS 244-564-8
1-propyl-1H-pyrrole-2,5-dione
MFCD00014541
N-(n-Propyl)maleimide

Chemical & Physical Properties

[ Density]:
1.073

[ Boiling Point ]:
97ºC18 mm Hg(lit.)

[ Melting Point ]:
24-26ºC

[ Molecular Formula ]:
C₇H₉NO₂

[ Molecular Weight ]:
139.15200

[ Flash Point ]:
95ºC

[ Exact Mass ]:
139.06300

[ PSA ]:
37.38000

[ LogP ]:
0.25930

[ Vapour Pressure ]:
0.0813mmHg at 25°C

[ Index of Refraction ]:
n20/D 1.4760(lit.)

[ Storage condition ]:
2-8°C

MSDS

Safety Information

[ Symbol ]:

GHS02, GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H226-H302-H317

[ Precautionary Statements ]:
P280

[ Hazard Codes ]:
Xi

[ Risk Phrases ]:
R20/21/22;R36/37/38

[ Safety Phrases ]:
S26-S36/37/39

[ RIDADR ]:
UN 1993 3/PG 3

[ Packaging Group ]:
III

[ HS Code ]:
2925190090

Synthetic Route

Click to get detail synthetic route

Customs

[ HS Code ]: 2925190090

[ Summary ]:
2925190090 other imides and their derivatives; salts thereof VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:30.0%

Articles

Antifungal, cytotoxic and SAR studies of a series of N-alkyl, N-aryl and N-alkylphenyl-1,4-pyrrolediones and related compounds.

Bioorg. Med. Chem. 19 , 2823-34, (2011)

The synthesis, in vitro evaluation and SAR studies of 67 maleimides and derivatives acting as antifungal agents are reported. A detailed SAR study supported by theoretical calculations led us to deter...

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