2-Methylimidazo[1,2-a]pyridine-3-carboxylic acid

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Names

[ CAS No. ]:
21801-79-6

[ Name ]:
2-Methylimidazo[1,2-a]pyridine-3-carboxylic acid

[Synonym ]:
Imidazo[1,2-a]pyridine-3-carboxylic acid, 2-methyl-
2-Methylimidazo[1,2-a]pyridine-3-carboxylic acid
MFCD00244615

Chemical & Physical Properties

[ Density]:
1.4±0.1 g/cm3

[ Boiling Point ]:
170ºC

[ Melting Point ]:
140ºC

[ Molecular Formula ]:
C9H8N2O2

[ Molecular Weight ]:
176.172

[ Exact Mass ]:
176.058578

[ PSA ]:
54.60000

[ LogP ]:
1.90

[ Index of Refraction ]:
1.653

MSDS

Click to get detail MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
NJ5495000
CHEMICAL NAME :
Imidazo(1,2-a)pyridine-3-carboxylic acid, 2-methyl-
CAS REGISTRY NUMBER :
21801-79-6
BEILSTEIN REFERENCE NO. :
0155092
LAST UPDATED :
199612
DATA ITEMS CITED :
1
MOLECULAR FORMULA :
C9-H8-N2-O2
MOLECULAR WEIGHT :
176.19
WISWESSER LINE NOTATION :
T56 AN DNJ BVQ C1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
600 mg/kg
TOXIC EFFECTS :
Behavioral - convulsions or effect on seizure threshold Behavioral - muscle contraction or spasticity Behavioral - irritability
REFERENCE :
JMCMAR Journal of Medicinal Chemistry. (American Chemical Soc., Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC 20037) V.6- 1963- Volume(issue)/page/year: 12,122,1969

Safety Information

[ Hazard Codes ]:
Xi: Irritant;

[ Risk Phrases ]:
R36/37/38

[ Safety Phrases ]:
26-36/37/39

[ HS Code ]:
2933990090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • 2-Aminopyridine
  • Ethyl 2-Chloroacetoacetate
  • 2-Methyl-imidazo[1,2-a]pyridine-3-carboxylic acid ethyl ester
  • 4H-Pyrido[1,2-a]pyrimidin-4-one,2-methyl-
  • 3-bromo-2-methylpyrido[1,2-a]pyrimidin-4-one
  • Methyl 2-methylimidazo[1,2-a]pyridine-3-carboxylate

DownStream

  • 3-Carbamoyl-2-methylimidazo(1,2-a)pyridine
  • Piperidine, 1-[(2-methylimidazo[1,2-a]pyridin-3-yl)carbonyl]- (9CI)

Customs

[ HS Code ]: 2933990090

[ Summary ]:
2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Related Compounds

  • 6-bromo-2-methylimidazo[1,2-a]pyridine-3-carboxylic acid
  • 6-chloro-2-methylimidazo[1,2-a]pyridine-3-carboxylic acid
  • 5-chloro-2-methylimidazo[1,2-a]pyridine-3-carboxylic acid
  • 7-Fluoro-2-methylimidazo[1,2-a]pyridine-3-carboxylic acid
  • 8-fluoro-2-methylimidazo[1,2-a]pyridine-3-carboxylic acid
  • 6-Fluoro-2-methylimidazo[1,2-a]pyridine-3-carboxylic acid
  • 4-((Cyclohexylamino)methyl)benzoic acid hydrochloride
  • 1-[(2,4-Dichlorophenyl)methyl]-N-(1,1-dimethylethyl)-2-methyl-1H-indole-3-methanamine
  • 2-Methoxy-6-(pyrazol-1-yl)-benzonitrile
  • 2-Fluoro-1-(pyridin-4-yl)ethan-1-ol
  • 1H-3-Benzazepin-7-ol, 8-chloro-2,3,4,5-tetrahydro-5-(3-iodophenyl)-3-methyl-, (S)-
  • 2-[3-(Piperidine-1-carbonyl)piperidin-1-yl]-3-(trifluoromethyl)pyridine
  • N,N'-Dimethyl-3-(phenylazo)-1,2-benzenediamine
  • (4-Methyl-tetrahydro-furan-2-yl)-methanol
  • N-(1-cyanocyclopentyl)-2-[4-(4-fluorobenzenesulfonyl)-1,4-diazepan-1-yl]acetamide
  • 4,5,6,7-Tetrahydrobenzo[d]isoxazole-3-carbaldehyde