4-bromo-1-azabicyclo[2.2.2]octane

Names

[ CAS No. ]:
2181-19-3

[ Name ]:
4-bromo-1-azabicyclo[2.2.2]octane

[Synonym ]:
4-Brom-chinuclidin
4-bromo-quinuclidine

Chemical & Physical Properties

[ Density]:
1.49g/cm3

[ Boiling Point ]:
201ºC at 760mmHg

[ Molecular Formula ]:
C7H12BrN

[ Molecular Weight ]:
190.08100

[ Flash Point ]:
75.4ºC

[ Exact Mass ]:
189.01500

[ PSA ]:
3.24000

[ LogP ]:
1.55750

[ Vapour Pressure ]:
0.315mmHg at 25°C

[ Index of Refraction ]:
1.573

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • 1-benzyl-4-bromo-quinuclidinium, bromide
  • N-Benzyl-4-piperidone
  • 1-benzyl-4-(2-hydroxyethyl)piperidin-4-ol
  • ethyl 2-(1-benzyl-4-hydroxypiperidin-4-yl)acetate
  • b-Alanine,N-(3-ethoxy-3-oxopropyl)-N-(phenylmethyl)-, ethyl ester
  • 1-benzyl-4-bromo-4-(2-bromo-ethyl)-piperidine, hydrobromide

DownStream

  • Quinuclidine

Related Compounds

  • 4-bromo-1-pentylbicyclo[2.2.2]octane
  • 4-bromo-1-propylbicyclo[2.2.2]octane
  • 4-ethyl-1-azabicyclo[2.2.2]octane
  • 4-methyl-1-azabicyclo[2.2.2]octane
  • 4-chloro-1-azabicyclo[2.2.2]octane
  • 4-nitro-1-azabicyclo[2.2.2]octane
  • 4,4-Difluoro-3-(3-fluoro-4-hydroxyphenyl)butanoic acid
  • 4-((Cyclohexylamino)methyl)benzoic acid hydrochloride
  • 1-[(2,4-Dichlorophenyl)methyl]-N-(1,1-dimethylethyl)-2-methyl-1H-indole-3-methanamine
  • 2-Methoxy-6-(pyrazol-1-yl)-benzonitrile
  • 1H-3-Benzazepin-7-ol, 8-chloro-2,3,4,5-tetrahydro-5-(3-iodophenyl)-3-methyl-, (S)-
  • 2-({[2-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)-1-methylcyclopentyl]formamido}oxy)propanoic acid
  • (4-Methyl-tetrahydro-furan-2-yl)-methanol
  • N-(1-cyanocyclopentyl)-2-[4-(4-fluorobenzenesulfonyl)-1,4-diazepan-1-yl]acetamide
  • 4,5,6,7-Tetrahydrobenzo[d]isoxazole-3-carbaldehyde
  • tert-Butyl-DL-alanine