4-bromo-1-azabicyclo[2.2.2]octane

Names

[ CAS No. ]:
2181-19-3

[ Name ]:
4-bromo-1-azabicyclo[2.2.2]octane

[Synonym ]:
4-Brom-chinuclidin
4-bromo-quinuclidine

Chemical & Physical Properties

[ Density]:
1.49g/cm3

[ Boiling Point ]:
201ºC at 760mmHg

[ Molecular Formula ]:
C7H12BrN

[ Molecular Weight ]:
190.08100

[ Flash Point ]:
75.4ºC

[ Exact Mass ]:
189.01500

[ PSA ]:
3.24000

[ LogP ]:
1.55750

[ Vapour Pressure ]:
0.315mmHg at 25°C

[ Index of Refraction ]:
1.573

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • 1-benzyl-4-bromo-quinuclidinium, bromide
  • N-Benzyl-4-piperidone
  • 1-benzyl-4-(2-hydroxyethyl)piperidin-4-ol
  • ethyl 2-(1-benzyl-4-hydroxypiperidin-4-yl)acetate
  • b-Alanine,N-(3-ethoxy-3-oxopropyl)-N-(phenylmethyl)-, ethyl ester
  • 1-benzyl-4-bromo-4-(2-bromo-ethyl)-piperidine, hydrobromide

DownStream

  • Quinuclidine

Related Compounds

  • 4-bromo-1-pentylbicyclo[2.2.2]octane
  • 4-bromo-1-propylbicyclo[2.2.2]octane
  • 4-ethyl-1-azabicyclo[2.2.2]octane
  • 4-methyl-1-azabicyclo[2.2.2]octane
  • 4-chloro-1-azabicyclo[2.2.2]octane
  • 4-nitro-1-azabicyclo[2.2.2]octane
  • Tert-butyl 3-{imidazo[1,2-a]pyridin-3-yl}piperazine-1-carboxylate
  • 1-{1-[3-Nitro-5-(trifluoromethyl)phenyl]cyclopropyl}cyclopropan-1-amine
  • Tert-butyl 2-(thian-3-yl)piperazine-1-carboxylate
  • (2S)-1-{pyrazolo[1,5-a]pyrimidin-2-yl}propan-2-amine
  • 1-(3-Fluoro-5-methylphenyl)-3-hydroxycyclobutane-1-carboxylic acid
  • 1-(3-Bromopyridin-4-yl)cyclopropane-1-carbaldehyde
  • 4-(5-Bromo-3-methylfuran-2-yl)butan-2-ol
  • methyl 4-(1-cyano-1-methylethyl)-1-methyl-1H-pyrazole-3-carboxylate
  • [2,2-Dimethyl-1-(4-methyl-1,3-thiazol-5-yl)cyclopropyl]methanol
  • 4-chloro-1-methyl-5-[(pyrrolidin-2-yl)methyl]-1H-imidazole