ANA-12

[ Molecular Formula ]:
C₂₂H₂₁N₃O₃S

[ Molecular Weight ]:
407.48500

[ Exact Mass ]:
407.13000

[ PSA ]:
126.01000

[ LogP ]:
4.78680

[ Appearance of Characters ]:
white to beige

[ Storage condition ]:
2-8°C

[ Water Solubility ]:
DMSO: ≥5mg/mL at 60°C

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H302

[ Hazard Codes ]:
Xn

[ Risk Phrases ]:
22

[ RIDADR ]:
NONH for all modes of transport

Epigenetic regulation of spinal cord gene expression controls opioid-induced hyperalgesia.

Mol. Pain 10 , 59, (2014)

The long term use of opioids for the treatment of pain leads to a group of maladaptations which includes opioid-induced hyperalgesia (OIH). OIH typically resolves within few days after cessation of mo...

HBZ stimulates brain-derived neurotrophic factor/TrkB autocrine/paracrine signaling to promote survival of human T-cell leukemia virus type 1-Infected T cells.

J. Virol. 88(22) , 13482-94, (2014)

Brain-derived neurotrophic factor (BDNF) is a neurotrophin that promotes neuronal proliferation, survival, and plasticity. These effects occur through autocrine and paracrine signaling events initiate...

7, 8-Dihydroxyflavone Protects an Endothelial Cell Line from H2O2 Damage.

PLoS ONE 10 , e0135345, (2015)

7, 8-dihydroxyflavone (7, 8-DHF), a selective agonist for TrkB receptors, has been well studied for its neurotrophic functions. However, its roles outside the neural tissues have scarcely been studied...

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