3',4'-dimethylacetanilide

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Names

[ CAS No. ]:
2198-54-1

[ Name ]:
3',4'-dimethylacetanilide

[Synonym ]:
3',4'-Acetoxylide
3',4'-Dimethyl-acetanilid
MFCD00026137
N-Acetyl-3,4-xylidine
EINECS 218-597-3
3,4-dimethylacetanilide
N-acetyl-3,4-dimethylbenzenamine
N-acetyl-3,4-dimethylaniline
N-(3,4-Dimethylphenyl)acetamide
3',4'-Acetoxylidide
3',4'-Dimethylacetanilide
3′,4′-Dimethylacetanilide

Chemical & Physical Properties

[ Density]:
1.052g/cm3

[ Boiling Point ]:
314.5ºC at 760mmHg

[ Melting Point ]:
96-98°C

[ Molecular Formula ]:
C10H13NO

[ Molecular Weight ]:
163.21600

[ Flash Point ]:
183.6ºC

[ Exact Mass ]:
163.10000

[ PSA ]:
29.10000

[ LogP ]:
2.33480

[ Vapour Pressure ]:
0.000465mmHg at 25°C

[ Index of Refraction ]:
1.56

MSDS

Click to get detail MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
AN7500000
CHEMICAL NAME :
3',4'-Acetoxylidide
CAS REGISTRY NUMBER :
2198-54-1
BEILSTEIN REFERENCE NO. :
0387706
LAST UPDATED :
199612
DATA ITEMS CITED :
2
MOLECULAR FORMULA :
C10-H13-N-O
MOLECULAR WEIGHT :
163.24
WISWESSER LINE NOTATION :
1VMR C1 D1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
1030 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
TXAPA9 Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1959- Volume(issue)/page/year: 19,20,1971 ** TUMORIGENIC DATA **
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
9900 mg/kg/56W-C
TOXIC EFFECTS :
Tumorigenic - equivocal tumorigenic agent by RTECS criteria Sense Organs and Special Senses (Ear) - effect, not otherwise specified Gastrointestinal - tumors
REFERENCE :
CNREA8 Cancer Research. (Public Ledger Building, Suit 816, 6th & Chestnut Sts., Philadelphia, PA 19106) V.1- 1941- Volume(issue)/page/year: 16,525,1956

Safety Information

[ Hazard Codes ]:
Xi

[ Risk Phrases ]:
R22

[ Safety Phrases ]:
S22-S36/37

[ RTECS ]:
AN7500000

[ HS Code ]:
2924299090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • Ethanoic anhydride
  • 3,4-Dimethylaniline
  • 3,4-Dimethylnitrobenzene
  • Potassium thioacetate
  • N-[1-(3,4-dimethylphenyl)ethylidene]hydroxylamine
  • 2,4-Pentandione
  • Acetonitrile
  • Nitroethane
  • o-xylene

DownStream

  • 2-amino-4,5-dimethylphenylamine
  • 2-Bromo-4,5-dimethylaniline
  • N-Ethyl-3,4-dimethylaniline
  • 4,5-Dimethyl-2-nitroaniline
  • 3,4-Dimethylaniline-6-sulfonic acid
  • 4',5'-Dimethyl-2'-nitroacetanilide
  • 2-Chloro-4,5-dimethylaniline
  • 4-Acetamido-2-Methylbenzoic Acid
  • 1,2-Dibromo-4,5-dimethylbenzene
  • 2-Amino-4,5-dimethylbenzoic acid

Customs

[ HS Code ]: 2924299090

[ Summary ]:
2924299090. other cyclic amides (including cyclic carbamates) and their derivatives; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

Related Compounds

  • 3',4'-DIMETHYL-3-(2,3-DIMETHYLPHENYL)PROPIOPHENONE
  • 3',4'-DIFLUORO-3-(1,3-DIOXAN-2-YL)-PROPIOPHENONE
  • 3',4'-dichloro-3-(1,3-dioxolan-2-yl)-propiophenone
  • 3',4'-DICHLORO-3,3-DIMETHYLBUTYROPHENONE
  • 3',4'-Dihydro-1'H,3H-spiro[1,3-benzothiazole-2,2'-naphthalene]
  • 3',4',5'-tridemethylepipodophyllotoxin