Escitalopram oxalate

Suppliers

Names

[ CAS No. ]:
219861-08-2

[ Name ]:
Escitalopram oxalate

[Synonym ]:
Lexapro (TN)
MFCD06407826
Lu-26-054-0
(1S)-1-[3-(diméthylamino)propyl]-1-(4-fluorophényl)-1,3-dihydro-2-benzofurane-5-carbonitrile oxalate
Ethandisäure--(1S)-1-[3-(dimethylamino)propyl]-1-(4-fluorphenyl)-1,3-dihydro-2-benzofuran-5-carbonitril(1:1)
ESCIFALOPRAMOXALATE
(S)-Citalopram Oxalate
(1S)-1-[3-(dimethylamino)propyl]-1-(4-fluorophenyl)-1,3-dihydro-2-benzofuran-5-carbonitrile ethanedioate
(1S)-1-[3-(Dimethylamino)propyl]-1-(4-fluorophenyl)-1,3-dihydro-2-benzofuran-5-carbonitrile ethanedioate (1:1)
Escitalopram oxalate (USAN)
Lexapro
escitalopram oxalic acid
Escitalopram Oxalate
Cipralex
(1S)-1-[3-(Dimethylamino)propyl]-1-(4-fluorophenyl)-1,3-dihydro-2-benzofuran-5-carbonitrile oxalate
5-Isobenzofurancarbonitrile, 1-[3-(dimethylamino)propyl]-1-(4-fluorophenyl)-1,3-dihydro-, (1S)-, ethanedioate (1:1)
(S)-Escitalopram Oxalate
Citalopram Impurity 2
Escitalopram (oxalate)

Chemical & Physical Properties

[ Boiling Point ]:
428.3ºC at 760 mmHg

[ Melting Point ]:
152-153ºC

[ Molecular Formula ]:
C₂₂H₂₃FN₂O₅

[ Molecular Weight ]:
414.427

[ Flash Point ]:
212.8ºC

[ Exact Mass ]:
414.159088

[ PSA ]:
110.86000

[ LogP ]:
2.96858

[ Storage condition ]:
-20°C Freezer, Under Inert Atmosphere

MSDS

Click to get detail MSDS

Safety Information

[ Hazard Codes ]:
Xi: Irritant;

[ Risk Phrases ]:
R36/37/38

[ Safety Phrases ]:
26-36

[ RIDADR ]:
NONH for all modes of transport

Precursor & DownStream

Precursor

Oxalic acid
Escitalopram
Formaldehyde
UNII:2FZ7LD4B44
(S)-citalopram (L)-tartrate
UNII:2FZ7LD4B44
1-Bromo-4-fluorobenzene
4-Fluorophenylmagnesium bromide
3-Chloro-N,N-dimethylpropan-1-amine hydrochloride
magnesium,N,N-dimethylpropan-1-amine,chloride

DownStream

Articles

The effect of combined treatment with risperidone and antidepressants on the MK-801-induced deficits in the social interaction test in rats.

Pharmacol. Rep. 67 , 1183-7, (2015)

Several clinical reports have suggested that augmentation of atypical antipsychotics' activity by antidepressants may efficiently improve the treatment of negative and some cognitive symptoms of schiz...

Prolonged administration of antidepressant drugs leads to increased binding of [(3)H]MPEP to mGlu5 receptors.

Neuropharmacology 84 , 46-51, (2014)

Metabotropic glutamate 5 (mGlu5) receptors are functionally connected with NMDA receptors. The antidepressant activity of the NMDA receptor antagonist ketamine in both preclinical and clinical studies...

Prenatal stress, regardless of concurrent escitalopram treatment, alters behavior and amygdala gene expression of adolescent female rats.

Neuropharmacology 97 , 251-8, (2015)

Depression during pregnancy has been linked to in utero stress and is associated with long-lasting symptoms in offspring, including anxiety, helplessness, attentional deficits, and social withdrawal. ...