(3S,6R,7S,8S,12R,13S,15S)-15-amino-12,13-epoxy-4,4,6,8,12,16-hexamethyl-3,7-dihydroxy-17-(2-methyl-4-thiazolyl)-5-oxo-16(E)-heptadecenoic acid

Names

[ CAS No. ]:
219990-25-7

[ Name ]:
(3S,6R,7S,8S,12R,13S,15S)-15-amino-12,13-epoxy-4,4,6,8,12,16-hexamethyl-3,7-dihydroxy-17-(2-methyl-4-thiazolyl)-5-oxo-16(E)-heptadecenoic acid

Chemical & Physical Properties

[ Molecular Formula ]:
C27H44N2O6S

[ Molecular Weight ]:
524.71300

[ Exact Mass ]:
524.29200

[ PSA ]:
174.51000

[ LogP ]:
4.66430

Synthetic Route

Precursor & DownStream

Precursor

  • (3S,6R,7S,8S,12R,13S,15S)-15-azido-12,13-epoxy-4,4,6,8,12,16-hexamethyl-3,7-dihydroxy-17-(2-methyl-4-thiazolyl)-5-oxo-16(E)-heptadecenoic acid

DownStream

  • Ixabepilone

Related Compounds

  • 2-cyclobutyl-3-[2-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)-3,3-dimethylbutanamido]propanoic acid
  • 2-cyclobutyl-3-{2-[({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)methyl]pentanamido}propanoic acid
  • 2-cyclobutyl-3-[(2S)-2-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)-3-methylpentanamido]propanoic acid
  • 2-cyclobutyl-3-{2-[2-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)acetamido]acetamido}propanoic acid
  • 2-cyclobutyl-3-[2-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)-4-(methylsulfanyl)butanamido]propanoic acid
  • rac-2-{1-[(1R,2S)-2-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)cyclopentyl]-N-(prop-2-yn-1-yl)formamido}acetic acid
  • rac-2-{[(1R,2S)-2-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)cyclopentyl]formamido}pent-4-ynoic acid
  • rac-2-{4-[(1R,2S)-2-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)cyclopentaneamido]-1H-pyrazol-1-yl}acetic acid
  • rac-5-{[(1R,2S)-2-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)cyclopentyl]formamido}-3-methylpentanoic acid
  • 2-{[2-cyclobutyl-3-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)propanamido]methyl}butanoic acid
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