NG,NG-Dimethylarginine Dihydrochloride

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Names

[ CAS No. ]:
220805-22-1

[ Name ]:
NG,NG-Dimethylarginine Dihydrochloride

[Synonym ]:
asym-Dimethylarginine ADMA
NG,NG-Dimethylarginine dihydrochloride
MFCD00270857
(Z)-N-[Amino(dimethylamino)methylene]-L-ornithine dihydrochloride
L-Ornithine, N-[amino(dimethylamino)methylene]-, (Z)-, hydrochloride (1:2)
NG,NG-DimethylarginineDihydrochloride
(2S)-2-amino-5-[[amino(dimethylamino)methylidene]amino]pentanoic acid,dihydrochloride

Chemical & Physical Properties

[ Boiling Point ]:
427.5ºC at 760 mmHg

[ Melting Point ]:
202-204OºC

[ Molecular Formula ]:
C8H20Cl2N4O2

[ Molecular Weight ]:
275.18

[ Flash Point ]:
212.4ºC

[ Exact Mass ]:
274.096344

[ PSA ]:
102.44000

[ LogP ]:
2.05940

[ Vapour Pressure ]:
1.66E-08mmHg at 25°C

MSDS

Click to get detail MSDS

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

Articles

Unique Features of Human Protein Arginine Methyltransferase 9 (PRMT9) and Its Substrate RNA Splicing Factor SF3B2.

J. Biol. Chem. 290 , 16723-43, (2015)

Human protein arginine methyltransferase (PRMT) 9 symmetrically dimethylates arginine residues on splicing factor SF3B2 (SAP145) and has been functionally linked to the regulation of alternative splic...

PRMT9 is a type II methyltransferase that methylates the splicing factor SAP145.

Nat. Commun. 6 , 6428, (2015)

The human genome encodes a family of nine protein arginine methyltransferases (PRMT1-9), whose members can catalyse three distinct types of methylation on arginine residues. Here we identify two splic...

Effects of nitric oxide synthase deficiency on a disintegrin and metalloproteinase domain-containing protein 12 expression in mouse brain samples.

Mol. Med. Report. 12 , 2253-62, (2015)

A disintegrin and metalloproteinase domain-containing protein 12 (ADAM12) belongs to the ADAM family of transmembrane proteins. Via proteolysis, cell adhesion, cell-cell fusion, cell-matrix interactio...


More Articles

Related Compounds

  • ng,ng'-dimethyl-l-arginine, dihydrochloride
  • NG,NG-dimethyl-L-Arginine-d6 (hydrochloride)
  • L-Arg(Me, Me)-OH (asymmetrical)
  • Nα,NG,NG-tribenzyloxycarbonylarginyl-(O-benzyl)serine
  • Nα,NG,NG-tribenzyloxycarbonylarginylalanine p-nitrobenzyl ester
  • 2-amino-5-[phenylmethoxycarbonyl-[(E)-N'-phenylmethoxycarbonylcarbamimidoyl]amino]pentanoic acid
  • 1-[3-(morpholine-4-sulfonyl)pyridin-2-yl]-N-{[4-(propan-2-yl)phenyl]methyl}piperidine-4-carboxamide
  • N-[(3-ethoxyphenyl)methyl]-1-[3-(morpholine-4-sulfonyl)pyridin-2-yl]piperidine-4-carboxamide
  • N-[(4-chlorophenyl)methyl]-1-[3-(morpholine-4-sulfonyl)pyridin-2-yl]piperidine-4-carboxamide
  • N-(2-chloro-4-fluorobenzyl)-1-(3-(morpholinosulfonyl)pyridin-2-yl)piperidine-4-carboxamide
  • 1-[3-(morpholine-4-sulfonyl)pyridin-2-yl]-N-(3-phenylpropyl)piperidine-4-carboxamide
  • 1-(3-(piperidin-1-ylsulfonyl)pyridin-2-yl)-N-(p-tolyl)piperidine-4-carboxamide
  • 1-Ethyl-N-(pentan-3-yl)-1H-pyrazol-4-amine
  • 2-(3-(4-chlorophenyl)-5-oxo-2,5-dihydro-1H-pyrazol-1-yl)-N-(2,3-dihydrobenzo[b][1,4]dioxin-6-yl)acetamide
  • N-(4-chlorophenyl)-2-(3-(4-fluorophenyl)-5-oxo-2,5-dihydro-1H-pyrazol-1-yl)acetamide
  • 2-(3-(4-fluorophenyl)-5-oxo-2,5-dihydro-1H-pyrazol-1-yl)-N-(2-methoxyphenyl)acetamide
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