6-T-BUTYL-2-METHYLPHENOL

Suppliers

Names

[ CAS No. ]:
2219-82-1

[ Name ]:
6-T-BUTYL-2-METHYLPHENOL

[Synonym ]:
2-Tert-Butyl-6-Methylphenol
2-Methyl-6-(2-methyl-2-propanyl)phenol
Phenol,2-(1,1-dimethylethyl)-6-methyl
MFCD00002239
2-(tert-Butyl)-6-methylphenol
6-tert-Butyl-o-cresol
6-T-BUTYL-2-METHYLPHENOL
2-tert-Butyl-6-methyl-phenol
EINECS 218-734-7
6-tert-Butyl-2-methylphenol
o-tert-Butyl-o-cresol
o-Cresol,6-tert-butyl
Phenol, 2-(1,1-dimethylethyl)-6-methyl-
2-tert-butyl-6-methyl phenol
2-methyl-6-tert-butyl-phenol
2-(1,1-dimethylethyl)-6-methylphenol
Phenol, 2- (1,1-dimethylethyl)-6-methyl-

Chemical & Physical Properties

[ Density]:
1.0±0.1 g/cm3

[ Boiling Point ]:
226.9±9.0 °C at 760 mmHg

[ Melting Point ]:
24-27 °C(lit.)

[ Molecular Formula ]:
C11H16O

[ Molecular Weight ]:
164.244

[ Flash Point ]:
107.2±0.0 °C

[ Exact Mass ]:
164.120117

[ PSA ]:
20.23000

[ LogP ]:
3.63

[ Vapour Pressure ]:
0.1±0.5 mmHg at 25°C

[ Index of Refraction ]:
1.513

MSDS

Click to get detail MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
SK1578200
CHEMICAL NAME :
Phenol, 2-tert-butyl-6-methyl-
CAS REGISTRY NUMBER :
2219-82-1
BEILSTEIN REFERENCE NO. :
1862362
LAST UPDATED :
199701
DATA ITEMS CITED :
2
MOLECULAR FORMULA :
C11-H16-O
MOLECULAR WEIGHT :
164.27
WISWESSER LINE NOTATION :
QR B1 FX1&1&1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
120 mg/kg
TOXIC EFFECTS :
Behavioral - sleep
REFERENCE :
JMCMAR Journal of Medicinal Chemistry. (American Chemical Soc., Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC 20037) V.6- 1963- Volume(issue)/page/year: 23,1350,1980

Safety Information

[ Symbol ]:

GHS05

[ Signal Word ]:
Danger

[ Hazard Statements ]:
H314

[ Precautionary Statements ]:
P280-P305 + P351 + P338-P310

[ Personal Protective Equipment ]:
Eyeshields;Faceshields;full-face particle respirator type N100 (US);Gloves;respirator cartridge type N100 (US);type P1 (EN143) respirator filter;type P3 (EN 143) respirator cartridges

[ Hazard Codes ]:
C:Corrosive;

[ Risk Phrases ]:
R34;R37

[ Safety Phrases ]:
S26-S28-S36/37/39-S45

[ RIDADR ]:
UN 2430 8/PG 1

[ WGK Germany ]:
3

[ RTECS ]:
SK1578200

[ Packaging Group ]:
III

[ Hazard Class ]:
8

[ HS Code ]:
2907199090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • o-cresol
  • Isobutylene
  • 2-tert-butyl-6-[(dimethylamino)methyl]phenol
  • Methanol
  • 2-tert-Butylphenol
  • 6-tert-butyl-2-(2'-methoxy-3'-tert-butyl-5'-methylbenzyl)-4-methylphenol
  • 4-bromo-2-(tert-butyl)-6-methylphenol
  • 4-Bromo-o-cresol
  • Butylated hydroxytoluene
  • 4-TERT-BUTYL-2-METHYLPHENOL

DownStream

  • 4-TERT-BUTYL-2-METHYLPHENOL
  • 2,4-Di-tert-butyl-6-methylphenol
  • o-cresol
  • 3,3-ditert-butyl-5,5-dimethyl[1,1-biphenyl]-4,4-diol
  • 2-tert-butyl-6-methyl-1,4-benzoquinone
  • 3-3'-Dimethyl-5-5'-ditert-butyl-diphenoquinone
  • 2-(TERT-BUTYL)-6-METHYLANILINE
  • 2,4-Xylenol, 6-tert-butyl-
  • 2-tert-butyl-4-[[3-[(3-tert-butyl-4-hydroxy-5-methylphenyl)methyl]-2-hydroxyphenyl]methyl]-6-methylphenol
  • 4,4'-Methylenebis(2-tert-butyl-6-methylphenol)

Customs

[ HS Code ]: 2907199090

[ Summary ]:
2907199090 other monophenols VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:5.5% General tariff:30.0%

Articles

Cellular apoptosis and cytotoxicity of phenolic compounds: a quantitative structure-activity relationship study.

J. Med. Chem. 48 , 7234-42, (2005)

In this comprehensive study on the caspase-mediated apoptosis-inducing effect of 51 substituted phenols in a murine leukemia cell line (L1210), we determined the concentrations needed to induce caspas...

Structure-based shape pharmacophore modeling for the discovery of novel anesthetic compounds.

Bioorg. Med. Chem. 17 , 5133-8, (2009)

Current anesthetics, especially the inhaled ones, have troublesome side effects and may be associated with durable changes in cognition. It is therefore highly desirable to develop novel chemical enti...


More Articles

Related Compounds

  • 6-t-butyl-2-(3,4,5,6-tetrachloro-2-hydroxyphenoxy)-1,3,6,2-dioxazaphosphocane 2-oxide
  • 6-t-Butyl-2(1,2-dihydroxyethyl)-phenol
  • 2-Bromo-4-tert-butyl-6-methyl-phenol
  • CaCCinh-A01
  • 2-tert-butyl-4,6-dimethylphenol,formic acid
  • 6-tert-butylnaphthalen-2-ol