3-(Difluoromethoxy)aniline

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Names

[ CAS No. ]:
22236-08-4

[ Name ]:
3-(Difluoromethoxy)aniline

[Synonym ]:
3-(Difluoromethoxy)aniline
3-Amino-α,α-difluoroanisole
α,α-Difluoro-m-anisidine
3-difluoromethoxyphenylamine
Benzenamine, 3-(difluoromethoxy)-
3-(Difluoromethoxy)benzenamine
3-difluoromethoxy aniline
ZR COYFF
MFCD00236221
m-difluoromethoxyaniline

Chemical & Physical Properties

[ Density]:
1.3±0.1 g/cm3

[ Boiling Point ]:
230.1±30.0 °C at 760 mmHg

[ Molecular Formula ]:
C7H7F2NO

[ Molecular Weight ]:
159.133

[ Flash Point ]:
92.9±24.6 °C

[ Exact Mass ]:
159.049576

[ PSA ]:
35.25000

[ LogP ]:
1.01

[ Vapour Pressure ]:
0.1±0.5 mmHg at 25°C

[ Index of Refraction ]:
1.502

MSDS

Click to get detail MSDS

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H315-H319-H335

[ Precautionary Statements ]:
P261-P305 + P351 + P338

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves

[ Hazard Codes ]:
Xi:Irritant;

[ Risk Phrases ]:
R36/37/38

[ Safety Phrases ]:
S26-S36

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

[ HS Code ]:
2922299090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • 3-(CHLORODIFLUOROMETHOXY)ANILINE

DownStream

  • 2-[3-(difluoromethoxy)anilino]benzoic acid

Preparation


Customs

[ HS Code ]: 2922299090

[ Summary ]:
2922299090. other amino-naphthols and other amino-phenols, other than those containing more than one kind of oxygen function, their ethers and esters; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

Related Compounds

  • 4-bromo-3-(difluoromethoxy)aniline
  • 4-chloro-3-(difluoromethoxy)aniline
  • 3-(difluoromethoxy)-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)aniline
  • 3,4-Bis(difluoromethoxy)aniline
  • 3-Chloro-5-(difluoromethoxy)aniline
  • 3-Bromo-5-(difluoromethoxy)aniline
  • 2-(3-{[(Tert-butoxy)carbonyl]amino}-4-methyl-5-(piperazin-1-yl)phenyl)acetic acid
  • Tert-butyl 4-[5-amino-3-(methoxycarbonyl)-2-methylphenyl]piperazine-1-carboxylate
  • Tert-butyl 4-[3-amino-5-(methoxycarbonyl)-4-methylphenyl]piperazine-1-carboxylate
  • 3-{4-[(Tert-butoxy)carbonyl]piperazin-1-yl}-2-methyl-5-(methylamino)benzoic acid
  • 5-{4-[(Tert-butoxy)carbonyl]piperazin-1-yl}-2-methyl-3-(methylamino)benzoic acid
  • 5-{[(Tert-butoxy)carbonyl](methyl)amino}-2-methyl-3-(piperazin-1-yl)benzoic acid
  • 3-{[(Tert-butoxy)carbonyl](methyl)amino}-2-methyl-5-(piperazin-1-yl)benzoic acid
  • 3-{[(Tert-butoxy)carbonyl](methyl)amino}-4-methyl-5-(piperazin-1-yl)benzoic acid
  • (9H-fluoren-9-yl)methyl 4-[3-amino-2,4,6-trimethyl-5-(prop-2-yn-1-yl)phenyl]piperazine-1-carboxylate
  • (9H-fluoren-9-yl)methyl N-{3-ethynyl-2,4,6-trimethyl-5-[(piperazin-1-yl)methyl]phenyl}carbamate
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