4-difluoromethoxyaniline

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Names

[ CAS No. ]:
22236-10-8

[ Name ]:
4-difluoromethoxyaniline

[Synonym ]:
ZR DOYFF
α,α-Difluoro-p-anisidine
4-(difluormethoxy)anilin
4-(OCF2H)aniline
4-(Difluoromethoxy)benzenamine
4-Amino-α,α-difluoroanisole
MFCD00085005
Benzenamine, 4-(difluoromethoxy)-
4-difluoromethoxyphenylamine
Benzeneamine, 4-(difluoromethoxy)
p-difluoromethoxyaniline
4-(Difluoromethoxy)aniline
4-difluoromethoxyaniline

Chemical & Physical Properties

[ Density]:
1.3±0.1 g/cm3

[ Boiling Point ]:
224.1±30.0 °C at 760 mmHg

[ Molecular Formula ]:
C7H7F2NO

[ Molecular Weight ]:
159.133

[ Flash Point ]:
89.3±24.6 °C

[ Exact Mass ]:
159.049576

[ PSA ]:
35.25000

[ LogP ]:
0.92

[ Vapour Pressure ]:
0.1±0.4 mmHg at 25°C

[ Index of Refraction ]:
1.502

MSDS

Click to get detail MSDS

Safety Information

[ Symbol ]:

GHS06

[ Signal Word ]:
Danger

[ Hazard Statements ]:
H301-H315-H319-H335

[ Precautionary Statements ]:
P261-P301 + P310-P305 + P351 + P338

[ Personal Protective Equipment ]:
Eyeshields;Faceshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter

[ Hazard Codes ]:
Xn:Harmful;

[ Risk Phrases ]:
R22;R36/37/38;R43

[ Safety Phrases ]:
S26-S36/37

[ RIDADR ]:
UN 2811 6.1/PG 3

[ WGK Germany ]:
2

[ Hazard Class ]:
6.1

[ HS Code ]:
2922299090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • 4-(Difluoromethoxy)nitrobenzene
  • 1-(Difluoromethoxy)-4-iodobenzene
  • Zinc
  • 2-Chloro-4,6-dimethylpyrimidine

DownStream

  • N-[4-(Difluoromethoxy)phenyl]acetamide
  • BMS-665053
  • N-[4-(difluoromethoxy)phenyl]-2-methylquinazolin-4-amine
  • ethyl 6-(difluoromethoxy)-2,3,4,9-tetrahydro-1h-carbazole-1-carboxylate
  • n-(p-(difluoromethoxy)phenyl)-anthranilicaci
  • Benzenamine, 4-(difluoromethoxy)-N-methyl- (9CI)

Preparation


Customs

[ HS Code ]: 2922299090

[ Summary ]:
2922299090. other amino-naphthols and other amino-phenols, other than those containing more than one kind of oxygen function, their ethers and esters; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

Related Compounds

  • 2-iodo-4-difluoromethoxyaniline
  • 3-methyl-4-difluoromethoxyaniline
  • 3-chloro-4-difluoromethoxyaniline
  • 4-chlorooxolan-3-ol,formic acid
  • 4-Amino-2-chloro-5-(1H-tetrazol-5-yl)benzenesulfonamide
  • 4-(4-Chlorophenyl)-4-Bromopiperide
  • [(1-ethyl-3-methyl-1H-pyrazol-4-yl)methyl](2-methylpropyl)amine
  • {[1-(2-Methylpropyl)-1H-indol-5-yl]methyl}(propyl)amine
  • 5-bromo-N-methyl-2-nitrobenzenesulfonamide
  • 4-(Tert-butylsulfanyl)-3,5-difluoroaniline
  • Cyclopropyl-[1-(3-methoxypropyl)-1H-indol-5-ylmethyl]-amine
  • Carbamic acid,[2-amino-4-chloro-5-(methylpropylamino)phenyl]-,1,1-dimethylethyl ester
  • N-[(4-cyanophenyl)methyl]-2-fluoropyridine-4-carboxamide
  • Benzyl 5-amino-1,3,4-thiadiazole-2-carboxylate
  • 4-[4-(Morpholin-4-yl)phenyl]butan-1-amine
  • N-(2-ethylcyclohexyl)-2-fluoropyridine-4-carboxamide
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