3,4-Dihydro-7-hydroxy-2(1H)-quinolinone

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Names

[ CAS No. ]:
22246-18-0

[ Name ]:
3,4-Dihydro-7-hydroxy-2(1H)-quinolinone

[Synonym ]:
2,7-quinolinediol, 3,4-dihydro-
3,4-Dihydro-7-hydroxycarbostyril
MFCD06410891
2(1H)-Quinolinone, 3,4-dihydro-7-hydroxy-
7-Hydroxy-2-oxo-1,2,3,4-tetrahydroquinoline
7-Hydroxy-3,4-dihydro-2(1H)-quinolinone
7-Hydroxy-3,4-dihydro-quinolin-2-one
7-Hydroxy-3,4-dihydrochinolin-2(1H)-on
7-hydroxy-3,4-dihydroquinolin-2(1H)-one
7-hydroxy-3,4-dihydro-2-quinolinone
7-Hydroxy-3,4-dihydro carbostyril
3,4-Dihydro-7-hydroxy-2(1H)-quinolinone
7-hydroxy-3,4-dihydro-2(1H)quinolinone
Brexpiprazole Impurity 5
Aripiprazole - Impurity A
7-​Hydroxy-​3,​4-​dihydro-​2(1H)​-​quinolinone

Chemical & Physical Properties

[ Density]:
1.3±0.1 g/cm3

[ Boiling Point ]:
403.7±45.0 °C at 760 mmHg

[ Melting Point ]:
233-237 °C

[ Molecular Formula ]:
C9H9NO2

[ Molecular Weight ]:
163.173

[ Flash Point ]:
198.0±28.7 °C

[ Exact Mass ]:
163.063324

[ PSA ]:
49.33000

[ LogP ]:
0.99

[ Vapour Pressure ]:
0.0±1.0 mmHg at 25°C

[ Index of Refraction ]:
1.604

MSDS

Click to get detail MSDS

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H302-H317

[ Precautionary Statements ]:
P280

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Faceshields;Gloves

[ Hazard Codes ]:
Xi: Irritant;Xn: Harmful;

[ Risk Phrases ]:
R22;R43

[ Safety Phrases ]:
S36/37

[ RIDADR ]:
NONH for all modes of transport

[ HS Code ]:
2933499090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • 3-Chloro-N-(3-methoxyphenyl)propanamide
  • CHEMBRDG-BB 6018839
  • 3-anisidine
  • 3-Chloropropanoyl chloride
  • 3-Aminophenol
  • N-(4-hydroxy-2-nitro-phenyl)acetamide
  • 7-Methoxy-3,4-dihydro-2(1H)-quinolinone
  • 3-(4-methoxy-2-nitrophenyl)acrylic acid methyl ester

DownStream

  • 7-Hydroxy-1,2,3,4-tetrahydroquinoline
  • Aripiprazole
  • 7-(4-Brombutoxy)-3,4-dihydrochinolin-2(1H)-on
  • 7-(4-Chlorobutoxy)-3,4-dihydro-2(1H)-quinolinone
  • 6-Bromo-7-hydroxy-3,4-dihydro-1H-quinolin-2-one
  • 1-Ethyl-1,2,3,4-tetrahydroquinoline-7-ol
  • 7-(4-iodobutoxy)-3,4-dihydro-1H-quinolin-2-one
  • 7-(3-chloropropoxy)-3,4-dihydro-1H-quinolin-2-one

Preparation


Customs

[ HS Code ]: 2933790090

[ Summary ]:
2933790090. other lactams. VAT:17.0%. Tax rebate rate:9.0%. . MFN tariff:9.0%. General tariff:20.0%

Related Compounds

  • 3,4-dihydro-7-(1-piperazinylcarbonyl)-2(1H)-quinolinone hydrochloride
  • 3,4-Dihydro-7-(4-hydroxybutoxy)-2(1H)-quinolinone
  • 6-Iodo-3,4-dihydro-2(1H)-quinolinone
  • N-Boc-3,4-Dihydro-2(1H)-Quinolinone
  • 6-Nitro-3,4-dihydro-2(1H)-quinolinone
  • 8-acetylamino-3,4-dihydro-2(1H)-quinolinone
  • 2-[(4,6-diaminopyrimidin-2-yl)sulfanyl]-N-[5-(methylsulfanyl)-1,3,4-thiadiazol-2-yl]acetamide
  • 2-(5-Methylenetetrahydro-2H-pyran-2-yl)acetic acid
  • 3-(4-Oxo-2-thioxo-3-thiazolidinyl)propane-1-sulfonic Acid
  • 5-methanesulfonyl-1H-1,2,3-triazole
  • 4,8-Dimethyl-1,2,3,4-tetrahydroquinoline
  • CID 15715392
  • (Z)-N-hydroxydocos-13-enamide
  • Ethyl 3-(4-methoxyphenyl)-2-oxopropanoate
  • 4-[(4-Methoxyphenyl)amino]benzeneacetic acid
  • N-(4-Aminophenyl)-2-(4-methoxyphenoxy)propanamide
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