Trimethoxystilbene

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Names

[ CAS No. ]:
22255-22-7

[ Name ]:
Trimethoxystilbene

[Synonym ]:
Trimethoxy-trans-stilbene
3,4',5-Trimethoxy-trans-stilbene
trimethoxy-trans-resveratrol
1,3-dimethoxy-5-[(E)-2-(4-methoxyphenyl)ethenyl]benzene
TRISMETHOXYRESVERATROL
resverarol trimethyl ether
1,3-Dimethoxy-5-[(E)-2-(4-methoxyphenyl)vinyl]benzene
1,3-dimethoxy-5-[(1E)-2-(4-methoxyphenyl)ethenyl]-benzene
methylated trans-resveratrol
(E)-1,3-Dimethoxy-5-(4-methoxystyryl)benzene
3,5,4'-Trimethoxystilbene
E-Resveratrol Trimethyl Ether
Resveratrol trimethyl ether
Benzene, 1,3-dimethoxy-5-[(E)-2-(4-methoxyphenyl)ethenyl]-
3,4',5-trimethoxystilbene
Tri-O-methylresveratrol
3,5,4'-TRIMETHOXY-TRANS-STILBENE
1,3-Dimethoxy-5-[(E)-2-(4-methoxy-phenyl)-vinyl]-benzene
O-permethylated E-resveratrol
trans-Trimethoxyresveratrol

Chemical & Physical Properties

[ Density]:
1.1±0.1 g/cm3

[ Boiling Point ]:
423.8±35.0 °C at 760 mmHg

[ Melting Point ]:
57ºC

[ Molecular Formula ]:
C17H18O3

[ Molecular Weight ]:
270.323

[ Flash Point ]:
144.4±23.2 °C

[ Exact Mass ]:
270.125580

[ PSA ]:
27.69000

[ LogP ]:
4.61

[ Vapour Pressure ]:
0.0±1.0 mmHg at 25°C

[ Index of Refraction ]:
1.600

[ Storage condition ]:
?20°C

[ Water Solubility ]:
DMSO: ≥34mg/mL

MSDS

Click to get detail MSDS

Safety Information

[ Symbol ]:

GHS05, GHS07, GHS09

[ Signal Word ]:
Danger

[ Hazard Statements ]:
H315-H318-H335-H410

[ Precautionary Statements ]:
P261-P273-P280-P305 + P351 + P338-P501

[ Hazard Codes ]:
Xi,N

[ Risk Phrases ]:
36/37/38

[ Safety Phrases ]:
26-36/37/39

[ RIDADR ]:
UN 3077 9 / PGIII

[ HS Code ]:
2909309090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • (+/-)-1-(3,5-dimethoxyphenyl)-2-(4-methoxyphenyl)ethanol
  • (3,5-DIMETHOXYBENZYL)TRIPHENYLPHOSPHONIUM BROMIDE
  • 4-Methoxybenzaldehyde
  • 3,5-dimethoxybenzyl 3,5-bis(trifluoromethyl)phenyl sulfone
  • 3,5-Dimethoxybenzaldehyde
  • Diethyl (4-methoxybenzyl)phosphonate
  • [3,5-bis(trifluoromethyl)phenyl] 3,5-dimethoxybenzyl sulfide
  • 3,5-DIMETHOXYBENZYL BROMIDE
  • Anisole
  • 4-Methoxybenzylchloride

DownStream

  • Resveratrol
  • 2,4,6-trimethoxyphenanthrene

Preparation


Customs

[ HS Code ]: 2909309090

[ Summary ]:
2909309090 other aromatic ethers and their halogenated, sulphonated, nitrated or nitrosated derivatives VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:5.5% General tariff:30.0%

Articles

Resveratrol analog-3,5,4'-trimethoxy-trans-stilbene inhibits invasion of human lung adenocarcinoma cells by suppressing the MAPK pathway and decreasing matrix metalloproteinase-2 expression.

Mol. Nutr. Food. Res. 53(3) , 407-16, (2009)

Resveratrol (3,5,4'-trihydroxystilbene) is a natural polyphenol that presents various physiological activities. It has been reported that the methylated derivatives of resveratrol show better potentia...

Trans- and cis-stilbene polyphenols induced rapid perinuclear mitochondrial clustering and p53-independent apoptosis in cancer cells but not normal cells.

Eur. J. Pharmacol. 587 , 25-34, (2008)

We previously reported that 3,4,5,4'-tetramethoxy-trans-stilbene (MR-4) induces p53 and perinuclear mitochondrial clustering in cancer cells [Gosslau, A., Chen, M., Ho, C.-T., Chen, K.Y., 2005, A meth...


More Articles

Related Compounds

  • 3,4,5-trimethoxystilbene
  • 3,4',5-trimethoxystilbene
  • 3,5,4'-trimethoxystilbene
  • 3,4,4'-trimethoxystilbene
  • (Z)-3,4,5-trimethoxystilbene
  • (E)-3,4,5-trimethoxystilbene
  • 1H-Pyrrole-1-carboxylic acid, 2-[[[(1,1-dimethylethyl)dimethylsilyl]oxy]methyl]-2,3-dihydro-, 1,1-dimethylethyl ester
  • 4-Pyridinamine, 2-chloro-5-(chloromethyl)-
  • 4-(Dimethylamino)-2,6-dimethylbenzenethiol
  • 5-(Methylthio)-2-(trifluoromethyl)benzonitrile
  • 2-[(2R)-2-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)-3-methyl-N-(prop-2-en-1-yl)butanamido]acetic acid
  • 2-(3-Amino-5-chlorophenyl)benzoic acid
  • 2,5-Difluoro-4-hydroxy-3-methoxybenzonitrile
  • 3,6-Difluoro-2-methoxytoluene
  • Benzyl 2-(hydroxymethyl)-5-phenylpyrrolidine-1-carboxylate
  • [(1,3-dimethyl-1H-pyrazol-4-yl)methyl](3-methoxypropyl)amine
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