2',4'-Dichloroacetophenone

Suppliers

Names

[ Name ]:
2',4'-Dichloroacetophenone

[Synonym ]:
2,4-dichoroacetophenone
Acetophenone,2',4'-dichloro
2‘,4‘-Dichloroacetophenone
2,4-Dichloroacetophenone
2',4'-dichloro phenyl ethanone
(2,4-Cl2-Ph)COMe
EINECS 218-780-8
1-(2,4-dichlorophenyl)ethanone
2’,4’-Dichloroacetophenone
p-Chloro-2-chloroacetophenone
2′,4′-Dichloroacetophenone
2`,4`-Dichloroacetophenone
2',4'-Dichloroacetophenone
MFCD00000581
Ethanone, 1-(2,4-dichlorophenyl)-

Chemical & Physical Properties

[ Density]:
1.3±0.1 g/cm3

[ Boiling Point ]:
246.7±20.0 °C at 760 mmHg

[ Melting Point ]:
33-34 °C(lit.)

[ Molecular Formula ]:
C₈H₆Cl₂O

[ Molecular Weight ]:
189.039

[ Flash Point ]:
100.9±22.3 °C

[ Exact Mass ]:
187.979568

[ PSA ]:
17.07000

[ LogP ]:
2.79

[ Vapour Pressure ]:
0.0±0.5 mmHg at 25°C

[ Index of Refraction ]:
1.549

[ Water Solubility ]:
ca. 200 mg/L

MSDS

Click to get detail MSDS

Safety Information

[ Symbol ]:

GHS05, GHS07

[ Signal Word ]:
Danger

[ Hazard Statements ]:
H302-H318

[ Precautionary Statements ]:
P280-P305 + P351 + P338

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves

[ Hazard Codes ]:
Xn:Harmful

[ Risk Phrases ]:
R22;R52/53

[ Safety Phrases ]:
S26-S39-S61

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
2

[ HS Code ]:
2914700090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

1-(2,4-Dichlorophenyl)ethanol
2,4-DICHLOROSTYRENE
Acetyl chloride
1,3-Dichlorobenzene
2,2',4'-Trichloroacetophenone
2-Bromo-2',4'-dichloroacetophenone
Benzamide, 2,4-dichloro-
2,4-Dichlorobenzoyl chloride
METHYLMAGNESIUM IODIDE

DownStream

1-(2,4-dichlorophenyl)-2-pyrazol-1-ylprop-2-en-1-one
1-[3-(2,4-dichlorophenyl)-3-oxoprop-1-en-2-yl]pyridin-2-one
2,4-Dichlorobenzoic acid
2,2',3,4,4',5-PCB
1-(2,4-DICHLOROPHENYL)-2-(1H-IMIDAZOLE-1-YL) ETHANONE
2,2,2',4'-tetrachloroacetophenone
2,2',4'-Trichloroacetophenone
(Z)-Chlorfenvinfos
BENZENEBUTANOIC ACID, 2,4-DICHLORO-.ALPHA.,.GAMMA.-DIOXO-, ETHYL ESTER
2',4'-DICHLOROCHALCONE

Customs

[ HS Code ]: 2914700090

[ Summary ]:
HS: 2914700090 halogenated, sulphonated, nitrated or nitrosated derivatives of ketones and quinones, whether or not with other oxygen function Tax rebate rate:9.0% Supervision conditions:none VAT:17.0% MFN tariff:5.5% General tariff:30.0%

Articles

Glutathione-dependent reductive dehalogenation of 2,2',4'-trichloroacetophenone to 2',4'-dichloroacetophenone.

Biochem. Pharmacol. 31(23) , 3885-90, (1982)

alpha-Haloketones are highly reactive compounds, which are known to undergo enzymatic reduction to methyl ketones. The objective of this research was to characterize the enzymes involved in this react...

[Synthesis of a new cyclodextrin derivative and its application as CGC chiral stationary phase in determination of enantiomeric excess].

Se Pu 20(1) , 34-6, (2002)

A new cyclodextrin (CD) derivative, 2,6-di-O-benzyl-3-O-valeryl-beta-CD, was synthesized and characterized by 1H NMR and IR. Using the beta-CD derivative as chiral stationary phase of capillary gas ch...

Microwave assisted rapid and efficient synthesis of nitrogen and sulphur containing heterocyclic compounds and their pharmacological evaluation.

Indian J. Chem. B 45(7) , 1762, (2006)

2',4'-Dichloroacetophenone
2',4'-Dichloroacetophenone
2',4'-dichloroacetophenone oxime
2-bromo-2',4'-dichloroacetophenone
2-Amino-2',4'-dichloroacetophenone
2-Bromo-2',4'-dichloroacetophenone
4-((Cyclohexylamino)methyl)benzoic acid hydrochloride
1-[(2,4-Dichlorophenyl)methyl]-N-(1,1-dimethylethyl)-2-methyl-1H-indole-3-methanamine
2-Methoxy-6-(pyrazol-1-yl)-benzonitrile
1H-3-Benzazepin-7-ol, 8-chloro-2,3,4,5-tetrahydro-5-(3-iodophenyl)-3-methyl-, (S)-
(4-Methyl-tetrahydro-furan-2-yl)-methanol
2-{[2-Hydroxy-2-(3-methylphenyl)ethyl]amino}propan-1-ol
N-(1-cyanocyclopentyl)-2-[4-(4-fluorobenzenesulfonyl)-1,4-diazepan-1-yl]acetamide
4,5,6,7-Tetrahydrobenzo[d]isoxazole-3-carbaldehyde
tert-Butyl-DL-alanine
2-(2,3,4-Trimethoxy-phenyl)-piperazine-1-carboxylic acid tert-butyl ester