YM-58483

Suppliers

Names

[ Name ]:
YM-58483

[Synonym ]:
N-{4-[3,5-Bis(trifluoromethyl)-1H-pyrazol-1-yl]phenyl}-4-methyl-1,2,3-thiadiazole-5-carboxamide
CRAC Channel Inhibitor,BTP2
btp2
1,2,3-Thiadiazole-5-carboxamide, N-[4-[3,5-bis(trifluoromethyl)-1H-pyrazol-1-yl]phenyl]-4-methyl-
YM-58483

Chemical & Physical Properties

[ Density]:
1.6±0.1 g/cm3

[ Molecular Formula ]:
C₁₅H₉F₆N₅OS

[ Molecular Weight ]:
421.320

[ Exact Mass ]:
421.043213

[ PSA ]:
100.94000

[ LogP ]:
3.77

[ Index of Refraction ]:
1.608

[ Storage condition ]:
-20℃

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H302-H315-H319-H335

[ Precautionary Statements ]:
P261-P305 + P351 + P338

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves

[ Hazard Codes ]:
Xn: Harmful;

[ Risk Phrases ]:
22-36/37/38

[ Safety Phrases ]:
26-36/37

[ RIDADR ]:
NONH for all modes of transport

Articles

Sodium entry through endothelial store-operated calcium entry channels: regulation by Orai1.

Am. J. Physiol. Cell Physiol. 308(4) , C277-88, (2015)

Orai1 interacts with transient receptor potential protein of the canonical subfamily (TRPC4) and contributes to calcium selectivity of the endothelial cell store-operated calcium entry current (ISOC)....

sodium,3-[(4-tert-butyl-1,3-thiazol-2-yl)methoxy]-N-[5-[3-(4-chlorophenyl)sulfonylpropyl]-2-(2H-tetrazol-5-ylmethoxy)phenyl]benzamide
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4-Amino-1-(1-methylcyclopropyl)cyclohexane-1-carboxylic acid
3-Amino-2-(2-bromo-3-hydroxyphenyl)propanoic acid
2-Amino-2-[1-(2-methoxypyridin-4-yl)cyclopropyl]acetic acid
2-Amino-3-(3-bromo-5-methylphenyl)-3-methylbutanoic acid
(3R)-3-amino-3-(1-benzyl-1H-pyrazol-4-yl)propanoic acid
1,4-Dioxa-10-azadispiro[4.2.4^{8}.2^{5}]tetradecane-12-carboxylic acid
2-(1-Amino-4,4-difluorocyclohexyl)-2-hydroxyacetic acid
4-(Aminomethyl)-1-(methoxymethyl)cyclohexane-1-carboxylic acid
2-Amino-3-[2-bromo-6-(trifluoromethyl)pyridin-4-yl]propanoicacid,trifluoroaceticacid
3-Amino-3-(2-bromo-1,3-thiazol-4-yl)propanoic acid