YM-58483

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Names

[ CAS No. ]:
223499-30-7

[ Name ]:
YM-58483

[Synonym ]:
N-{4-[3,5-Bis(trifluoromethyl)-1H-pyrazol-1-yl]phenyl}-4-methyl-1,2,3-thiadiazole-5-carboxamide
CRAC Channel Inhibitor,BTP2
btp2
1,2,3-Thiadiazole-5-carboxamide, N-[4-[3,5-bis(trifluoromethyl)-1H-pyrazol-1-yl]phenyl]-4-methyl-
YM-58483

Chemical & Physical Properties

[ Density]:
1.6±0.1 g/cm3

[ Molecular Formula ]:
C15H9F6N5OS

[ Molecular Weight ]:
421.320

[ Exact Mass ]:
421.043213

[ PSA ]:
100.94000

[ LogP ]:
3.77

[ Index of Refraction ]:
1.608

[ Storage condition ]:
-20℃

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H302-H315-H319-H335

[ Precautionary Statements ]:
P261-P305 + P351 + P338

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves

[ Hazard Codes ]:
Xn: Harmful;

[ Risk Phrases ]:
22-36/37/38

[ Safety Phrases ]:
26-36/37

[ RIDADR ]:
NONH for all modes of transport

Articles

Sodium entry through endothelial store-operated calcium entry channels: regulation by Orai1.

Am. J. Physiol. Cell Physiol. 308(4) , C277-88, (2015)

Orai1 interacts with transient receptor potential protein of the canonical subfamily (TRPC4) and contributes to calcium selectivity of the endothelial cell store-operated calcium entry current (ISOC)....


More Articles

Related Compounds

  • sodium,3-[(4-tert-butyl-1,3-thiazol-2-yl)methoxy]-N-[5-[3-(4-chlorophenyl)sulfonylpropyl]-2-(2H-tetrazol-5-ylmethoxy)phenyl]benzamide
  • YM 298198 HYDROCHLORIDE
  • YM 758
  • YM 750
  • YM 511
  • YM 26734
  • 4-(5-(2-Nitrophenyl)furan-2-yl)thiazol-2-amine
  • 4-(5-(4-Aminophenyl)furan-2-yl)thiazol-2-amine
  • N-(2-Amino-4'-methyl-[4,5'-bithiazol]-2'-yl)propionamide
  • 4-(2,3,5,6-Tetramethylphenyl)-2-thiazolamine
  • 4-[2-Fluoro-6-(trifluoromethyl)phenyl]-2-thiazolamine
  • 4-(2-Fluoro-4-(trifluoromethyl)phenyl)thiazol-2-amine
  • 4-(4-Fluoro-2-(trifluoromethyl)phenyl)thiazol-2-amine
  • 4-(3,4,5-Trifluoro-phenyl)-thiazol-2-ylamine
  • 4-[2-(3-Aminophenyl)-4-thiazolyl]-1,3-benzenediol
  • 3-Ethoxy-4-methoxy-N-(1-methylbutyl)benzenemethanamine
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