Benzo[m]tetraphene

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Names

[ CAS No. ]:
224-41-9

[ Name ]:
Benzo[m]tetraphene

[Synonym ]:
dibenz<a,j>anthracene
3,4,5,6-Dibenzanthracene
EINECS 205-928-1
Benzo[m]tetraphene
dibenz<a,j>acridine
Dibenz<a,j>anthracen
Dibenz[a,j]anthracene
Dibenzo<a,j>anthracen
1,2,7,8-Dibenzanthracene
Dibenzo-1,2,7,8-anthracene

Chemical & Physical Properties

[ Density]:
1.2±0.1 g/cm3

[ Boiling Point ]:
524.7±17.0 °C at 760 mmHg

[ Melting Point ]:
197.5°C

[ Molecular Formula ]:
C22H14

[ Molecular Weight ]:
278.347

[ Flash Point ]:
264.5±15.1 °C

[ Exact Mass ]:
278.109558

[ LogP ]:
7.14

[ Vapour Pressure ]:
0.0±0.7 mmHg at 25°C

[ Index of Refraction ]:
1.812

[ Storage condition ]:
2-8°C

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
HN2800000
CHEMICAL NAME :
Dibenz(a,j)anthracene
CAS REGISTRY NUMBER :
224-41-9
BEILSTEIN REFERENCE NO. :
2051201
LAST UPDATED :
199710
DATA ITEMS CITED :
13
MOLECULAR FORMULA :
C22-H14
MOLECULAR WEIGHT :
278.36
WISWESSER LINE NOTATION :
L E6 D6 B666J

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Administration onto the skin
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
252 mg/kg/81W-I
TOXIC EFFECTS :
Tumorigenic - equivocal tumorigenic agent by RTECS criteria Skin and Appendages - tumors Tumorigenic - tumors at site of application
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Subcutaneous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
4 mg/kg
TOXIC EFFECTS :
Tumorigenic - equivocal tumorigenic agent by RTECS criteria Tumorigenic - tumors at site of application
TYPE OF TEST :
TD - Toxic dose (other than lowest)
ROUTE OF EXPOSURE :
Administration onto the skin
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
1250 mg/kg/52W-I
TOXIC EFFECTS :
Tumorigenic - equivocal tumorigenic agent by RTECS criteria Skin and Appendages - tumors Tumorigenic - tumors at site of application
TYPE OF TEST :
TD - Toxic dose (other than lowest)
ROUTE OF EXPOSURE :
Subcutaneous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
16 mg/kg
TOXIC EFFECTS :
Tumorigenic - equivocal tumorigenic agent by RTECS criteria Tumorigenic - tumors at site of application
TYPE OF TEST :
TD - Toxic dose (other than lowest)
ROUTE OF EXPOSURE :
Subcutaneous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
4 mg/kg
TOXIC EFFECTS :
Tumorigenic - equivocal tumorigenic agent by RTECS criteria Tumorigenic - tumors at site of application

MUTATION DATA

TYPE OF TEST :
Mutation in mammalian somatic cells
TEST SYSTEM :
Human Lymphocyte
DOSE/DURATION :
53 ug/L
REFERENCE :
MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 371,123,1996 *** REVIEWS *** IARC Cancer Review:Animal Limited Evidence IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) V.1- 1972- Volume(issue)/page/year: 32,309,1983 IARC Cancer Review:Human No Adequate Data IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) V.1- 1972- Volume(issue)/page/year: 32,309,1983 IARC Cancer Review:Group 3 IMSUDL IARC Monographs, Supplement. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) No.1- 1979- Volume(issue)/page/year: 7,56,1987 TOXICOLOGY REVIEW 85DHAX "Medical and Biologic Effects of Environmental Pollutants Series," Washington, DC, National Academy of Sciences, 1972-77 Volume(issue)/page/year: Pc,4,1972

Safety Information

[ Symbol ]:

GHS06

[ Signal Word ]:
Danger

[ Hazard Statements ]:
H301-H315-H319-H335

[ Precautionary Statements ]:
P261-P301 + P310-P305 + P351 + P338

[ Hazard Codes ]:
T

[ Risk Phrases ]:
25-36/37/38-52/53

[ Safety Phrases ]:
26-45-61

[ RIDADR ]:
UN 2811

[ Packaging Group ]:
III

[ Hazard Class ]:
6.1(b)

[ HS Code ]:
2902909090

Synthetic Route

Precursor & DownStream

Precursor

  • 2,4',6',2''-tetravinyl-[1,1',3',1'']terphenyl
  • 3-(naphthalen-2-yl)naphtho[1,2-c]furan-1(3H)-one
  • 2-(2-naphthoyl)-1-naphthoic acid
  • 1,3-Bis[(E)-styryl]benzene
  • 1,2-Phenylenediacetic Acid
  • 1,3-phenylenebis(ethane-2,1-diyl) dimethanesulfonate

DownStream

Customs

[ HS Code ]: 2902909090

[ Summary ]:
2902909090 other aromatic hydrocarbons。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:2.0%。General tariff:30.0%

Articles

Microsomal metabolism of dibenz[a,c]anthracene, dibenz[a,h]anthracene and dibenz[a,j]anthracene to bis-dihydrodiols and polyhydroxylated products.

Chem. Biol. Interact. 80(3) , 261-79, (1991)

Polar, ethyl acetate soluble metabolites formed in incubations of dibenz[a,c]anthracene (DB[a,c]A), dibenz[a,h]anthracene (DB[a,h]A) and the related DB[a,h]A 3,4-diol and dibenz[a,j]anthracene (DB[a,j...

Comparison of the in vitro metabolisms and mutagenicities of dibenzo[a,c]anthracene, dibenzo[a,h]anthracene and dibenzo[a,j]anthracene: influence of norharman.

Carcinogenesis 10(3) , 461-9, (1989)

The comparison of the behaviour of three dibenzoanthracene (DBA) isomers, dibenzo[a,c]anthracene (DB[a,c]A), dibenzo[a,h]anthracene (DB[a,h]A) and dibenzo[a,j]anthracene (DB[a,j]A), polycyclic aromati...

Dibenz[a,j]anthracene.

IARC Monogr. Eval. Carcinog. Risk Chem. Hum. 32 , 309-13, (1983)


More Articles


Related Compounds

  • 3-methoxybenzo[m]tetraphene
  • benzo[m]tetraphene-3,4-dione
  • Benzo[m]tetraphene-5,6-dione
  • 5,6-dihydrobenzo[m]tetraphene
  • 7,14-Dihydrobenzo[m]tetraphene
  • 7,14-dimethylbenzo[m]tetraphene
  • 1-[(Tert-butoxy)carbonyl]-4-(carboxymethyl)piperidine-2-carboxylic acid
  • 5-(2,4-Dimethylphenyl)isoxazole-4-carboxylic acid
  • 2-(5-bromopyridin-2-yl)-N,N-dimethylethanamine
  • Ethyl 3-[[3-(hydroxymethyl)phenyl]sulfonyl]benzoate
  • 3-bromo-N-cyclopentyl-N-methylaniline
  • (4-Ethyl-6-methylpyrimidin-2-yl)methanamine
  • 4-[6-(4-Nitro-phenoxy)pyrimidin-4-ylamino]phenol
  • 4-bromo-N,N-diethyl-3-fluorobenzenesulfonamide
  • 2-bromo-1-methoxy-4-[(E)-2-methoxyethenyl]benzene
  • Benzyl 3-(4-(hydroxymethyl)-3-methylphenoxy)propanoate
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