BIS(7)-TACRINE
Suppliers
Names
[ CAS No. ]:
224445-12-9
[ Name ]:
BIS(7)-TACRINE
[Synonym ]:
N,N'-Di(1,2,3,4-tetrahydro-9-acridinyl)-1,7-heptanediamine dihydrochloride
9-Amino-1,2,3,4-tetrahydroacridine bis 1,7-heptylene dihydrochloride
Tacrine-Based Inhibitor 2f
heptylene-bis(tacrine) dihydrochloride heptylene-bis(THA) dihydrochloride
1,7-Heptanediamine, N,N-bis(1,2,3,4-tetrahydro-9-acridinyl)-, hydrochloride (1:2)
Chemical & Physical Properties
[ Molecular Formula ]:
C33H42Cl2N4
[ Molecular Weight ]:
565.619
[ Exact Mass ]:
564.278625
[ PSA ]:
49.84000
[ LogP ]:
9.76510
Safety Information
[ Hazard Codes ]:
T: Toxic;
[ Risk Phrases ]:
25-36/37/38
[ Safety Phrases ]:
26-36-45
[ RIDADR ]:
UN 2811 6.1/PG 3
Articles
J. Chem. Soc. Perkin Trans. I , 171, (1997)
J. Biol. Chem. 271 , 23646, (1996)
We report highly potent, selective, and low cost bifunctional acetylcholinesterase (AChE) inhibitors developed by our two-step prototype optimization strategy utilizing computer modeling of ligand doc...