Hydroxocobalamin Acetate
Suppliers
Names
[ CAS No. ]:
22465-48-1
[ Name ]:
Hydroxocobalamin Acetate
[Synonym ]:
Hydroxocobalamin acetate
Vitamin B12a acetate
HYDROXOCOBALAMIN ACETATE
Chemical & Physical Properties
[ Melting Point ]:
>300ºC.
[ Molecular Formula ]:
C64H91CoN13O16P
[ Molecular Weight ]:
1388.39000
[ Exact Mass ]:
1387.58000
[ PSA ]:
490.17000
[ LogP ]:
6.62930
MSDS
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- GG3740000
- CHEMICAL NAME :
- Cobinamide, acetate (salt) hydroxide, dihydrogen phosphate (ester), inner salt, 3'-ester with 5,6-dimethyl-1-alpha-D-ribofuranosylbenzimidazole
- CAS REGISTRY NUMBER :
- 22465-48-1
- LAST UPDATED :
- 199409
- DATA ITEMS CITED :
- 1
- MOLECULAR FORMULA :
- C64-H91-Co-N13-O16-P
- MOLECULAR WEIGHT :
- 1388.58
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 2 gm/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- NIIRDN Drugs in Japan (Ethical Drugs). (Yakugyo Jiho Co., Ltd., Tokyo, Japan) Volume(issue)/page/year: 6,622,1982
Safety Information
[ Symbol ]:
GHS08
[ Signal Word ]:
Warning
[ Hazard Statements ]:
H351
[ Precautionary Statements ]:
P280
[ RIDADR ]:
NONH for all modes of transport
[ RTECS ]:
GG3740000
Articles
Mol. Genet. Metab. 97 , 260-266, (2009)
The MMACHC gene product of the cblC complementation group, referred to as the cblC protein, catalyzes the in vitro and in vivo decyanation of cyanocobalamin (vitamin B(12)). We hypothesized that the c...
Chem. Soc. Rev. 40 , 4346-4363, (2011)
B(12)-cofactors play important roles in the metabolism of microorganisms, animals and humans. Microorganisms are the only natural sources of B(12)-derivatives, and the latter are "vitamins" for other ...
ACS Chem. Biol. 1 , 149-159, (2006)
Many coenzymes are vitamins that are assimilated in mammals into their active form from precursors obtained from the diet. They are often both rare and reactive rendering the likelihood low that the c...