2-piperazin-1-yl-1H-quinazolin-4-one

Names

[ CAS No. ]:
22587-11-7

[ Name ]:
2-piperazin-1-yl-1H-quinazolin-4-one

[Synonym ]:
2-Piperazino-3H,4-quinazolone
2-Piperazin-1-yl-3H-quinazolin-4-one

Chemical & Physical Properties

[ Density]:
1.41g/cm3

[ Boiling Point ]:
411.3ºC at 760mmHg

[ Molecular Formula ]:
C12H14N4O

[ Molecular Weight ]:
230.26600

[ Flash Point ]:
202.5ºC

[ Exact Mass ]:
230.11700

[ PSA ]:
61.28000

[ LogP ]:
1.13880

[ Vapour Pressure ]:
5.65E-07mmHg at 25°C

[ Index of Refraction ]:
1.719

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
VA4179100
CHEMICAL NAME :
4(3H)-Quinazolinone, 2-(1-piperazinyl)-
CAS REGISTRY NUMBER :
22587-11-7
BEILSTEIN REFERENCE NO. :
0884695
LAST UPDATED :
199612
DATA ITEMS CITED :
1
MOLECULAR FORMULA :
C12-H14-N4-O
MOLECULAR WEIGHT :
230.30

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
800 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
IJOCAP Indian Journal of Chemistry. (New Delhi, India) V.1-13, 1963-75. Divided into Indian Journal of Chemistry, Section A and Indian Journal of Chemistry, Section B. Volume(issue)/page/year: 9,201,1971

Synthetic Route

Click to get detail synthetic route

Related Compounds

  • acetic acid,2-piperazin-1-yl-1H-quinazolin-4-one
  • 5,6,7-trimethoxy-2-[4-(4-methoxy-pyridin-2-yl)-piperazin-1-yl]-1H-quinazolin-4-one
  • 2-piperidin-1-yl-1H-quinazolin-4-one
  • 2-naphthalen-1-yl-1H-quinazolin-4-one
  • 2-(azepan-1-yl)-1H-quinazolin-4-one
  • 2-[3-[4-(4-fluorophenyl)piperazin-1-yl]propyl]-8-methoxy-1H-quinazolin-4-one
  • 4-((Cyclohexylamino)methyl)benzoic acid hydrochloride
  • 1-[(2,4-Dichlorophenyl)methyl]-N-(1,1-dimethylethyl)-2-methyl-1H-indole-3-methanamine
  • 2-Methoxy-6-(pyrazol-1-yl)-benzonitrile
  • 6-methyl-1-[(prop-2-en-1-yloxy)carbonyl]-1H,2H,3H,4H-imidazo[1,5-a]pyrimidine-8-carboxylic acid
  • (2R)-2-{ethyl[(prop-2-en-1-yloxy)carbonyl]amino}-3-phenylpropanoic acid
  • 1H-3-Benzazepin-7-ol, 8-chloro-2,3,4,5-tetrahydro-5-(3-iodophenyl)-3-methyl-, (S)-
  • (4-Methyl-tetrahydro-furan-2-yl)-methanol
  • N-(1-cyanocyclopentyl)-2-[4-(4-fluorobenzenesulfonyl)-1,4-diazepan-1-yl]acetamide
  • 4,5,6,7-Tetrahydrobenzo[d]isoxazole-3-carbaldehyde
  • tert-Butyl-DL-alanine