Etanidazole
Suppliers
Names
[ CAS No. ]:
22668-01-5
[ Name ]:
Etanidazole
[Synonym ]:
Etanidazol
Ethanidazole
Etanidazole
1H-Imidazole-1-acetamide,N-(2-hydroxyethyl)-2-nitro
N-(2-hydroxyethyl)-2-(2-nitroimidazol-1-yl)acetamide
UNII:30DKA3Q1HL
N-(2-hydroxyethyl)-2-nitro-1H-imidazole-1-acetamide
1H-Imidazole-1-acetamide, N-(2-hydroxyethyl)-2-nitro-
Etanidazol [Spanish]
N-(2-hydroxyethyl)-2-nitroimidazole-1-acetamide
1-{N-(2-hydroxyethyl)-acetamido}-2-nitroimidazole
N-(2-Hydroxyethyl)-2-(2-nitro-1H-imidazol-1-yl)acetamide
Radinyl
SR-2508
Etanidazolum
Chemical & Physical Properties
[ Density]:
1.6±0.1 g/cm3
[ Boiling Point ]:
354.3°C (rough estimate)
[ Melting Point ]:
162-163° (Beaman); mp 164.5-165° (Lee)
[ Molecular Formula ]:
C7H10N4O4
[ Molecular Weight ]:
214.179
[ Exact Mass ]:
214.070206
[ PSA ]:
112.97000
[ LogP ]:
-1.66
[ Index of Refraction ]:
1.646
[ Storage condition ]:
2-8°C
MSDS
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- NI3355000
- CHEMICAL NAME :
- Imidazole-1-acetamide, N-(2-hydroxyethyl)-2-nitro-
- CAS REGISTRY NUMBER :
- 22668-01-5
- BEILSTEIN REFERENCE NO. :
- 0919296
- LAST UPDATED :
- 199612
- DATA ITEMS CITED :
- 6
- MOLECULAR FORMULA :
- C7-H10-N4-O4
- MOLECULAR WEIGHT :
- 214.21
- WISWESSER LINE NOTATION :
- T5N CNJ A1VM2Q BNW
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 3716 mg/kg
- TOXIC EFFECTS :
- Behavioral - somnolence (general depressed activity) Musculoskeletal - other changes Biochemical - Enzyme inhibition, induction, or change in blood or tissue levels - transaminases
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 3300 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 4100 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Unreported
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 4900 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Unreported
- SPECIES OBSERVED :
- Mammal - species unspecified
- DOSE/DURATION :
- 4900 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
MUTATION DATA
- TYPE OF TEST :
- Morphological transformation
- TEST SYSTEM :
- Rodent - mouse Embryo
- DOSE/DURATION :
- 1 mmol/L/3D (Continuous)
- REFERENCE :
- 45OJAG "Radiation Sensitizers: Their Use in the Clinical Management of Cancer, Proceedings of the Conference, Key Biscayne, FL, 1979," Brady, L.W., ed., New York, Masson Pub. USA, Inc., 1980 Volume(issue)/page/year: -,146,1980
Safety Information
[ Hazard Codes ]:
Xi: Irritant;
[ Risk Phrases ]:
36/37/38
[ Safety Phrases ]:
26-36
[ WGK Germany ]:
3
[ RTECS ]:
NI3355000
[ HS Code ]:
2933290090
Customs
[ HS Code ]: 2933290090
[ Summary ]:
2933290090. other compounds containing an unfused imidazole ring (whether or not hydrogenated) in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%