Oxyclozanide
Suppliers
Names
[ CAS No. ]:
2277-92-1
[ Name ]:
Oxyclozanide
[Synonym ]:
2,3,5-Trichlor-N-(3,5-dichlor-2-hydroxyphenyl)-6-hydroxybenzolcarboxamid
MFCD00864507
Zanilox
Oxyclozanide
diplin
3,3',5,5',6-Pentachloro-2'-hydroxysalicylanilid
EINECS 218-904-0
OXYCLOZAMIDE
Oxycloxanide
zanil
Saucylanilide
Benzamide, 2,3,5-trichloro-N-(3,5-dichloro-2-hydroxyphenyl)-6-hydroxy-
3,3',5,5',6-pentachloro-2'-hydroxysalicylanilide
2,3,5-Trichloro-N-(3,5-dichloro-2-hydroxyphenyl)-6-hydroxybenzamide
oxyclozanid
Chemical & Physical Properties
[ Density]:
1.8±0.1 g/cm3
[ Boiling Point ]:
446.0±45.0 °C at 760 mmHg
[ Melting Point ]:
205 - 210ºC
[ Molecular Formula ]:
C13H6Cl5NO3
[ Molecular Weight ]:
401.457
[ Flash Point ]:
223.5±28.7 °C
[ Exact Mass ]:
398.879028
[ PSA ]:
69.56000
[ LogP ]:
8.67
[ Vapour Pressure ]:
0.0±1.1 mmHg at 25°C
[ Index of Refraction ]:
1.722
[ Storage condition ]:
0-6°C
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- CV8576000
- CHEMICAL NAME :
- Benzanilide, 2,2'-dihydroxy-3,3',5,5',6-pentachloro-
- CAS REGISTRY NUMBER :
- 2277-92-1
- LAST UPDATED :
- 199612
- DATA ITEMS CITED :
- 4
- MOLECULAR FORMULA :
- C13-H6-Cl5-N-O3
- MOLECULAR WEIGHT :
- 401.45
- WISWESSER LINE NOTATION :
- QR BG DG FMVR BQ CG EG FG
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 1 gm/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- NATUAS Nature. (Nature Subscription Dept., POB 1018, Manasguan, NJ 08736) V.1- 1869- Volume(issue)/page/year: 210,744,1966
- TYPE OF TEST :
- LDLo - Lowest published lethal dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Mammal - domestic
- DOSE/DURATION :
- 60 mg/kg
- TOXIC EFFECTS :
- Behavioral - muscle weakness Gastrointestinal - hypermotility, diarrhea Nutritional and Gross Metabolic - weight loss or decreased weight gain
- REFERENCE :
- VETRAX Veterinary Record. (7 Mansfield St., London W1M 0AT, UK) V.1- 1888- Volume(issue)/page/year: 78,267,1966
- TYPE OF TEST :
- LDLo - Lowest published lethal dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Mammal - cattle
- DOSE/DURATION :
- 60 mg/kg
- TOXIC EFFECTS :
- Behavioral - convulsions or effect on seizure threshold Behavioral - coma Lungs, Thorax, or Respiration - respiratory stimulation
- REFERENCE :
- VETRAX Veterinary Record. (7 Mansfield St., London W1M 0AT, UK) V.1- 1888- Volume(issue)/page/year: 78,267,1966
- TYPE OF TEST :
- LDLo - Lowest published lethal dose
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Mammal - domestic
- DOSE/DURATION :
- 10 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- VETRAX Veterinary Record. (7 Mansfield St., London W1M 0AT, UK) V.1- 1888- Volume(issue)/page/year: 78,267,1966
Safety Information
[ Symbol ]:
GHS07, GHS09
[ Signal Word ]:
Warning
[ Hazard Statements ]:
H302-H410
[ Precautionary Statements ]:
P273-P501
[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves
[ Hazard Codes ]:
Xn:Harmful;N:Dangerousfortheenvironment;
[ Risk Phrases ]:
R22;R50/53
[ Safety Phrases ]:
S60-S61
[ RIDADR ]:
UN 3077
[ RTECS ]:
CV8576000
[ HS Code ]:
2924299090
Customs
[ HS Code ]: 2924299090
[ Summary ]:
2924299090. other cyclic amides (including cyclic carbamates) and their derivatives; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%
Articles
Turkiye. Parazitol. Derg. 32(2) , 134-8, (2008)
The aim of this study was to investigate the effectiveness of tablet and paste formulations of Oxfendazole and Oxyclozanide combinations against subclinical gastrointestinal nematode infections and to...
J. AOAC Int. 93(4) , 1340-6, (2010)
LC/MS/MS was developed to determine the residues of bithionol (BTN), bromofen (BMF), nitroxynil (NTX), oxyclozanide (OCZ), and tribromsalan (TBS) in milk. Samples were extracted with ethyl acetate and...
Vet. Parasitol. 45(1-2) , 81-8, (1992)
An improved hemagglutination (HA) test using the purified specific f2 antigen of Fasciola hepatica has been evaluated with regard to its potential use for the prediction of chemotherapeutic success in...