Famprofazone

Names

[ CAS No. ]:
22881-35-2

[ Name ]:
Famprofazone

[Synonym ]:
Famprofazone
Famprofazona [INN-Spanish]
Famprofazonum [INN-Latin]

Chemical & Physical Properties

[ Density]:
1.083g/cm3

[ Boiling Point ]:
485.1ºC at 760mmHg

[ Molecular Formula ]:
C₂₄H₃₁N₃O

[ Molecular Weight ]:
377.52200

[ Flash Point ]:
184.8ºC

[ Exact Mass ]:
377.24700

[ PSA ]:
30.17000

[ LogP ]:
4.36240

[ Vapour Pressure ]:
1.45E-09mmHg at 25°C

[ Index of Refraction ]:
1.574

MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: UQ9451000

CHEMICAL NAME :: Pyrazolin-5-one, 4-isopropyl-2-methyl-1-phenyl-3-((1-phenyl-2-propyl)m ethylamino)methyl-

CAS REGISTRY NUMBER :: 22881-35-2

LAST UPDATED :: 199612

DATA ITEMS CITED :: 1

MOLECULAR FORMULA :: C24-H31-N3-O

MOLECULAR WEIGHT :: 377.58

WISWESSER LINE NOTATION :: T5NNVJ A1 BR& DY1&1 E1N1&Y1&1R

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 2 gm/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: SMWOAS Schweizerische Medizinische Wochenschrift. (Schwabe & Co., Steintorst 13, 4010 Basel, Switzerland) V.50- 1920- Volume(issue)/page/year: 84,351,1954

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H302

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves

[ Hazard Codes ]:
Xn: Harmful;

[ Risk Phrases ]:
22

[ Safety Phrases ]:
36

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

[ RTECS ]:
UQ9451000

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Articles

Illegal or legitimate use? Precursor compounds to amphetamine and methamphetamine.

Drug Metab. Rev. 32(1) , 15-44, (2000)

The interpretation of methamphetamine and amphetamine positive test results in biological samples is a challenge to clinical and forensic toxicology for several reasons. The effects of pH and dilution...

Detection and identification of famprofazone and its metabolite in human urine.

J. Chromatogr. B, Biomed. Appl. 661(2) , 255-61, (1994)

Detection and identification of famprofazone and its metabolite, p-hydroxydesmethylfamprofazone, were described. The identity of the new metabolite was confirmed by comparing its mass spectrum and gas...

Urinary methamphetamine concentration following famprofazone administration.

J. Anal. Toxicol. 18(5) , 265-8, (1994)

A 37-year-old man had a considerable concentration of methamphetamine in his urine, but he denied taking any abused drug. It was found that he took a pain killer that contains famprofazone, a relative...