2-Bromo-5-methoxybenzoic acid

Suppliers

Names

[ Name ]:
2-Bromo-5-methoxybenzoic acid

[Synonym ]:
MFCD00020214
6-Bromo-m-anisic Acid
2-Bromo-5-methoxybenzoicacid
5-methoxy-2-bromobenzoic acid
2-Brom-5-methoxy-benzoesaeure
Benzoic acid, 2-bromo-5-methoxy-
6-bromo-3-methoxybenzoic acid
2-Bromo-5-methoxybenzoic acid
EINECS 245-329-2

Chemical & Physical Properties

[ Density]:
1.6±0.1 g/cm3

[ Boiling Point ]:
337.8±27.0 °C at 760 mmHg

[ Melting Point ]:
157-159 °C(lit.)

[ Molecular Formula ]:
C₈H₇BrO₃

[ Molecular Weight ]:
231.043

[ Flash Point ]:
158.1±23.7 °C

[ Exact Mass ]:
229.957855

[ PSA ]:
46.53000

[ LogP ]:
2.53

[ Vapour Pressure ]:
0.0±0.8 mmHg at 25°C

[ Index of Refraction ]:
1.584

MSDS

Click to get detail MSDS

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ Hazard Codes ]:
Xi

[ Risk Phrases ]:
R36/37/38

[ Safety Phrases ]:
S26-S36

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

[ HS Code ]:
2918990090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

3-Methoxybenzoic acid
(2-Bromo-5-methoxyphenyl)methanol
6-bromo-3-methoxy-2-(trimethylsilyl)benzoic acid
3-methoxy-2-(trimethylsilyl)benzoic acid
2-Bromo-5-methoxybenzonitrile
1-Bromo-4-methoxy-2-nitrobenzene
2-Bromo-5-methoxyaniline
4-(3-methoxyphenyl)butanoic acid
2-Bromo-5-methoxybenzaldehyde
3-Methylanisole

DownStream

Methyl 2-bromo-5-methoxybenzoate
6-Methoxy-2H-3,1-benzoxazine-2,4(1H)-dione
2-benzoyl-5-methoxy-benzoic acid
5-Bromo-2-(carboxymethyl)benzoic acid
2-(4-fluorophenyl)-5-methoxybenzoic acid
2-bromo-5-methoxy-N,N-dimethylbenzamide
5-methoxy-2-methylsulfanylbenzoic acid
3-Methoxybenzoic acid
tert-Butyl 2-bromo-5-methoxybenzoate
2-Bromo-5-hydroxybenzoic acid

Preparation

Customs

[ HS Code ]: 2918990090

[ Summary ]:
2918990090. other carboxylic acids with additional oxygen function and their anhydrides, halides, peroxides and peroxyacids; their halogenated, sulphonated, nitrated or nitrosated derivatives. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

Articles

Pomegranate ellagitannin-derived compounds exhibit antiproliferative and antiaromatase activity in breast cancer cells in vitro.

Cancer Prev. Res. (Phila.) 3(1) , 108-13, (2010)

Estrogen stimulates the proliferation of breast cancer cells and the growth of estrogen-responsive tumors. The aromatase enzyme, which converts androgen to estrogen, plays a key role in breast carcino...

Synthesis of substituted aminobenzacridines.

J. Am. Chem. Soc. 68 , 1599-1602, (1946)

Potential metabolites of clorotepin: 2-and 3-hydroxy derivatives of 8-chloro-10-(4-methylpiperazino)-10, 11-dihydrodibenzo [b, f] thiepin and their methyl ethers. Šindelár, K., et al.

Collect. Czech. Chem. Commun. 39(12) , 3548-3559., (1974)

2-bromo-5-methoxybenzoic acid chloride
2-bromo-5-methoxybenzoic acid ethyl ester
2-Bromo-5-methoxybenzoic Acid Methyl Ester
2-Bromo-5-methoxybenzoic Acid Methyl Ester
2-Bromo-5-ethoxy-4-methoxybenzoic acid
2-Bromo-5-fluoro-4-methoxybenzoic acid
6-(4-benzylpiperidine-1-carbonyl)-2-methylpyridazin-3(2H)-one
Ethyl 4-(1-methyl-6-oxo-1,6-dihydropyridazine-3-carbonyl)piperazine-1-carboxylate
6-[4-(Furan-2-carbonyl)piperazine-1-carbonyl]-2-methyl-2,3-dihydropyridazin-3-one
N-(3,4-dimethoxyphenethyl)-1-methyl-6-oxo-1,6-dihydropyridazine-3-carboxamide
2-methyl-6-(1,2,3,4-tetrahydroisoquinoline-2-carbonyl)pyridazin-3(2H)-one
1-methyl-6-oxo-N-(thiophen-2-ylmethyl)-1,6-dihydropyridazine-3-carboxamide
N-(3,4-difluorophenyl)-1-methyl-6-oxo-1,6-dihydropyridazine-3-carboxamide
Ethyl 4-(1-methyl-6-oxo-1,6-dihydropyridazine-3-carboxamido)benzoate
1-methyl-N-(6-nitrobenzo[d]thiazol-2-yl)-6-oxo-1,6-dihydropyridazine-3-carboxamide
1-methyl-N-(5-methylisoxazol-3-yl)-6-oxo-1,6-dihydropyridazine-3-carboxamide

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