indole-3-glyoxylyl chloride

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Names

[ CAS No. ]:
22980-09-2

[ Name ]:
indole-3-glyoxylyl chloride

[Synonym ]:
MFCD00015460
2-indol-3-yl-2-oxoacetyl chloride
Indole-3-Glyoxylyl Chloride
Indole-3-glyoxyloyl chloride
EINECS 245-362-2
3-Indoleglyoxylyl chloride
3-indoleglyoxyl chloride
3-indolylglyoxalyl chloride
2-(3-indolyl)-2-oxo acetyl chloride
1h-indol-3-yl(oxo)acetyl chloride

Chemical & Physical Properties

[ Density]:
1.463 g/cm3

[ Boiling Point ]:
413.9ºC at 760 mmHg

[ Melting Point ]:
138 °C (dec.)(lit.)

[ Molecular Formula ]:
C10H6ClNO2

[ Molecular Weight ]:
207.61300

[ Flash Point ]:
204.1ºC

[ Exact Mass ]:
207.00900

[ PSA ]:
49.93000

[ LogP ]:
2.11600

[ Vapour Pressure ]:
4.63E-07mmHg at 25°C

[ Index of Refraction ]:
1.676

[ Storage condition ]:
2-8°C

MSDS

Click to get detail MSDS

Safety Information

[ Symbol ]:

GHS05

[ Signal Word ]:
Danger

[ Hazard Statements ]:
H314

[ Precautionary Statements ]:
P280-P305 + P351 + P338-P310

[ Personal Protective Equipment ]:
Eyeshields;Faceshields;full-face particle respirator type N100 (US);Gloves;respirator cartridge type N100 (US);type P1 (EN143) respirator filter;type P3 (EN 143) respirator cartridges

[ Hazard Codes ]:
C: Corrosive;

[ Risk Phrases ]:
R34

[ Safety Phrases ]:
S26-S27-S36/37/39-S45

[ RIDADR ]:
UN 1759 8/PG 2

[ WGK Germany ]:
3

[ Packaging Group ]:
II

[ Hazard Class ]:
8

[ HS Code ]:
2918300090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • Indole
  • Oxalyl chloride
  • 1H-Indol-3-yl(oxo)acetic acid
  • 4-Methoxyindole
  • oxalic acid chloride

DownStream

  • 2-(1-Benzyl-1H-indol-3-yl)-2-oxoacetamide
  • Dimethyltryptamine
  • (1H-Indol-3-yl)-oxo-acetic acid ethyl ester
  • 2-(1-METHYL-1H-INDOL-3-YL)-2-OXOACETIC ACID METHYL ESTER
  • Methyl 3-indolecarboxylate
  • 2-(1H-indol-3-yl)-N-methyl-2-oxo-acetamide
  • 1H-Indole-3-acetamide,N,N-dimethyl-α-oxo-
  • Ethyl 1H-indole-3-carboxylate
  • 3-Indoleacetic acid
  • 1H-Indole-3-carboxylic acid

Preparation


Customs

[ HS Code ]: 2918300090

[ Summary ]:
2918300090 other carboxylic acids with aldehyde or ketone function but without other oxygen function, their anhydrides, halides, peroxides, peroxyacids and their derivatives。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:6.5%。General tariff:30.0%

Articles

Lasting chemiluminescence of 3-indoleglyoxylyl chloride and its enhancement.

Anal. Sci. 19(1) , 123-7, (2003)

The chemiluminescence (CL) intensities of various indole derivatives substituted with a glyoxylyl group at the 3-position and a hydroxyl group at the 5-position of the indole ring were compared upon t...

Notes-Concerning a preparation of tryptamine. Brutcher J, et al.

J. Org. Chem. 23(1) , 146-147, (1958)

A concise synthesis of an AHR endogenous ligand with the indolecarbonylthiazole skeleton. Grzywacz P, et al.

Heterocycles 60(5) , 1219-1224, (2003)


More Articles

Related Compounds

  • Indole-3-Glyoxylyl Chloride
  • 6-bromoindole-3-glyoxylyl chloride
  • 1-methylindole-3-glyoxylyl chloride
  • 6-methoxyindole-3-glyoxylyl chloride
  • 1-methyl-7-nitroindole-3-glyoxylyl chloride
  • indole-3-propionic acid chloride
  • 2-(Diethylamino)propyl 4-methylbenzene-1-sulfonate
  • 3,5-Diiodopyridin-4-yl 4-methylbenzene-1-sulfonate
  • 3,5-Dimethylhex-1-yn-3-yl 4-methylbenzene-1-sulfonate
  • Octa-2,4-dien-1-yl 4-methylbenzene-1-sulfonate
  • 3,6-Dimethylpyridazin-4-yl 4-methylbenzene-1-sulfonate
  • (3,5-Dibromothiophen-2-yl)methyl 4-methylbenzene-1-sulfonate
  • 2-Chloro-5-iodophenyl 4-methylbenzene-1-sulfonate
  • 2,2,3,3-Tetramethylcyclobutyl 4-methylbenzene-1-sulfonate
  • 6-[(Propylamino)methyl]piperidin-2-one
  • (6-Chloropyridin-2-yl)methyl 4-methylbenzene-1-sulfonate