Pregn-4-ene-3,20-dione, 6-alpha-fluoro-

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Names

[ CAS No. ]:
2300-03-0

[ Name ]:
Pregn-4-ene-3,20-dione, 6-alpha-fluoro-

[Synonym ]:
21-Acetoxy-6|A-fluoro-11|A-hydroxy-16|A-methylpregna-1,4-diene-3,20-dione
21-Acetoxyfluocortolone
Fluocortolone Acetate

Chemical & Physical Properties

[ Density]:
1.12g/cm3

[ Boiling Point ]:
449.3ºC at 760mmHg

[ Molecular Formula ]:
C21H29FO2

[ Molecular Weight ]:
332.45200

[ Flash Point ]:
169.7ºC

[ Exact Mass ]:
332.21500

[ PSA ]:
34.14000

[ LogP ]:
4.67150

[ Vapour Pressure ]:
2.9E-08mmHg at 25°C

[ Index of Refraction ]:
1.53

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
TU5023400
CHEMICAL NAME :
Pregn-4-ene-3,20-dione, 6-alpha-fluoro-
CAS REGISTRY NUMBER :
2300-03-0
BEILSTEIN REFERENCE NO. :
3218997
LAST UPDATED :
199612
DATA ITEMS CITED :
1
MOLECULAR FORMULA :
C21-H29-F-O2
MOLECULAR WEIGHT :
332.50

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Subcutaneous
DOSE :
400 ug/kg
SEX/DURATION :
female 1 day(s) pre-mating
TOXIC EFFECTS :
Reproductive - Maternal Effects - uterus, cervix, vagina
REFERENCE :
85GRAA "The Control of Fertility," Pincus, G., New York, Academic Press, 1965 Volume(issue)/page/year: -,150,1965

Related Compounds

  • Pregn-4-ene-3,20-dione,6-fluoro-11,17,21-trihydroxy-, (6a,11b)-
  • Pregn-4-ene-3,20-dione,6-fluoro-17,21-dihydroxy-16-methyl-, (6a,16a)- (9CI)
  • Pregn-4-ene-3,20-dione,6-fluoro-14,17,21-trihydroxy-16-methyl-, (6a,16a)- (9CI)
  • 6-fluoroprogesterone
  • Pregn-4-ene-3,20-dione,21-(acetyloxy)-6-fluoro-16,17-[(1-methylethylidene)bis(oxy)]-, (6a,16a)- (9CI)
  • Pregn-4-ene-3,20-dione,21-(acetyloxy)-6-fluoro-11,17-dihydroxy-, (6a,11b)- (9CI)
  • 2-[1-(Morpholine-4-carbonyl)piperidin-4-yl]-6-(pyrimidin-5-yl)-1,8-naphthyridine
  • N-(1-{7-methyl-7H-pyrrolo[2,3-d]pyrimidin-4-yl}piperidin-3-yl)cyclopropanecarboxamide
  • 9-methyl-6-{4-[6-(1H-pyrazol-1-yl)pyrimidin-4-yl]piperazin-1-yl}-9H-purine
  • 2-(4-Benzoylpiperazin-1-yl)-5-chloropyrimidine
  • 2-Methyl-3-{4-[2-methyl-6-(oxan-4-yl)pyrimidin-4-yl]piperazin-1-yl}quinoxaline
  • [6-(trifluoromethyl)cyclohex-3-en-1-yl]methanamine;hydrochloride
  • Methyl 4,5-dihydro-5-methyl-2-(1-methylcyclopropyl)-4-oxazolecarboxylate
  • 2,4-dichloro-6-(2,5-dihydro-3-furanyl)Pyridine
  • ((2S,5S,Z)-Hex-3-ene-2,5-diyl)bis(bis(3,5-dimethylphenyl)phosphane)
  • N-{2-[5-(1-methyl-1H-pyrazol-4-yl)thiophen-2-yl]ethyl}-2-(methylsulfanyl)benzamide