Pregn-4-ene-3,20-dione, 6-alpha-fluoro-

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Names

[ CAS No. ]:
2300-03-0

[ Name ]:
Pregn-4-ene-3,20-dione, 6-alpha-fluoro-

[Synonym ]:
21-Acetoxy-6|A-fluoro-11|A-hydroxy-16|A-methylpregna-1,4-diene-3,20-dione
21-Acetoxyfluocortolone
Fluocortolone Acetate

Chemical & Physical Properties

[ Density]:
1.12g/cm3

[ Boiling Point ]:
449.3ºC at 760mmHg

[ Molecular Formula ]:
C21H29FO2

[ Molecular Weight ]:
332.45200

[ Flash Point ]:
169.7ºC

[ Exact Mass ]:
332.21500

[ PSA ]:
34.14000

[ LogP ]:
4.67150

[ Vapour Pressure ]:
2.9E-08mmHg at 25°C

[ Index of Refraction ]:
1.53

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
TU5023400
CHEMICAL NAME :
Pregn-4-ene-3,20-dione, 6-alpha-fluoro-
CAS REGISTRY NUMBER :
2300-03-0
BEILSTEIN REFERENCE NO. :
3218997
LAST UPDATED :
199612
DATA ITEMS CITED :
1
MOLECULAR FORMULA :
C21-H29-F-O2
MOLECULAR WEIGHT :
332.50

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Subcutaneous
DOSE :
400 ug/kg
SEX/DURATION :
female 1 day(s) pre-mating
TOXIC EFFECTS :
Reproductive - Maternal Effects - uterus, cervix, vagina
REFERENCE :
85GRAA "The Control of Fertility," Pincus, G., New York, Academic Press, 1965 Volume(issue)/page/year: -,150,1965

Related Compounds

  • Pregn-4-ene-3,20-dione,6-fluoro-11,17,21-trihydroxy-, (6a,11b)-
  • Pregn-4-ene-3,20-dione,6-fluoro-17,21-dihydroxy-16-methyl-, (6a,16a)- (9CI)
  • Pregn-4-ene-3,20-dione,6-fluoro-14,17,21-trihydroxy-16-methyl-, (6a,16a)- (9CI)
  • 6-fluoroprogesterone
  • Pregn-4-ene-3,20-dione,21-(acetyloxy)-6-fluoro-16,17-[(1-methylethylidene)bis(oxy)]-, (6a,16a)- (9CI)
  • Pregn-4-ene-3,20-dione,21-(acetyloxy)-6-fluoro-11,17-dihydroxy-, (6a,11b)- (9CI)
  • tert-butyl N-(5-bromo-2-chloro-3-nitrophenyl)carbamate
  • Tert-butyl 5-formyl-2-(trifluoromethyl)morpholine-4-carboxylate
  • N-methyl-1-(1H-pyrrol-3-yl)cyclopropan-1-amine
  • 2-[5-(5,6,7,8-tetrahydronaphthalen-1-yl)-1H-1,3-benzodiazol-2-yl]ethan-1-amine
  • 1-(6-Bromo-2,3-dihydro-1-benzofuran-2-yl)-2-methylpropan-1-one
  • 1-(1,3-Oxazol-2-yl)cyclobutan-1-amine hydrochloride
  • Methyl 2-(aminomethyl)-4-methyl-1,3-thiazole-5-carboxylate dihydrochloride
  • Tert-butyl 4-{bicyclo[1.1.1]pentan-1-yl}piperazine-1-carboxylate
  • Benzyl 4-{[5-(4-bromophenyl)thiophen-2-yl]methyl}piperazine-1-carboxylate
  • 2-(1-Bromoethyl)-1-fluoro-4-nitrobenzene
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