Pregn-4-ene-3,20-dione, 6-alpha-fluoro-

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Names

[ Name ]:
Pregn-4-ene-3,20-dione, 6-alpha-fluoro-

[Synonym ]:
21-Acetoxy-6|A-fluoro-11|A-hydroxy-16|A-methylpregna-1,4-diene-3,20-dione
21-Acetoxyfluocortolone
Fluocortolone Acetate

Chemical & Physical Properties

[ Density]:
1.12g/cm3

[ Boiling Point ]:
449.3ºC at 760mmHg

[ Molecular Formula ]:
C₂₁H₂₉FO₂

[ Molecular Weight ]:
332.45200

[ Flash Point ]:
169.7ºC

[ Exact Mass ]:
332.21500

[ PSA ]:
34.14000

[ LogP ]:
4.67150

[ Vapour Pressure ]:
2.9E-08mmHg at 25°C

[ Index of Refraction ]:
1.53

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: TU5023400

CHEMICAL NAME :: Pregn-4-ene-3,20-dione, 6-alpha-fluoro-

CAS REGISTRY NUMBER :: 2300-03-0

BEILSTEIN REFERENCE NO. :: 3218997

LAST UPDATED :: 199612

DATA ITEMS CITED :: 1

MOLECULAR FORMULA :: C21-H29-F-O2

MOLECULAR WEIGHT :: 332.50

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Subcutaneous

DOSE :: 400 ug/kg

SEX/DURATION :: female 1 day(s) pre-mating

TOXIC EFFECTS :: Reproductive - Maternal Effects - uterus, cervix, vagina

REFERENCE :: 85GRAA "The Control of Fertility," Pincus, G., New York, Academic Press, 1965 Volume(issue)/page/year: -,150,1965

Related Compounds

Pregn-4-ene-3,20-dione,6-fluoro-11,17,21-trihydroxy-, (6a,11b)-
Pregn-4-ene-3,20-dione,6-fluoro-17,21-dihydroxy-16-methyl-, (6a,16a)- (9CI)
Pregn-4-ene-3,20-dione,6-fluoro-14,17,21-trihydroxy-16-methyl-, (6a,16a)- (9CI)
6-fluoroprogesterone
Pregn-4-ene-3,20-dione,21-(acetyloxy)-6-fluoro-16,17-[(1-methylethylidene)bis(oxy)]-, (6a,16a)- (9CI)
Pregn-4-ene-3,20-dione,21-(acetyloxy)-6-fluoro-11,17-dihydroxy-, (6a,11b)- (9CI)
(R)-1-(2-(Benzyloxy)-5-fluorophenyl)propan-2-ol
(2S)-4-bromo-2-phenyl-1,2-dihydroimidazo[1,2-a]quinoline
4-(3-Methylphenyl)-D-phenylalanine
Tert-butyl 7-bromo-3-formyl-1h-indole-1-carboxylate
1-(2,6-Dimethylmorpholin-4-yl)-3-fluoropropan-2-ol
N-(2,4-dimethoxyphenyl)-6-hydroxypyrimidine-4-carboxamide
2-Phenyl-5,6,7,8-tetrahydro-4H-pyrazolo[1,5-a][1,4]diazepin-4-one
N-(3-acetylphenyl)-6-hydroxypyrimidine-4-carboxamide
3-[2-[(2-methylpropan-2-yl)oxycarbonyl]-3,4-dihydro-1H-isoquinolin-7-yl]propanoic acid
Methyl 5-(N-hydroxycarbamimidoyl)-2-methylbenzoate

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