Pregn-4-ene-3,20-dione, 6-alpha-fluoro-

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Names

[ CAS No. ]:
2300-03-0

[ Name ]:
Pregn-4-ene-3,20-dione, 6-alpha-fluoro-

[Synonym ]:
21-Acetoxy-6|A-fluoro-11|A-hydroxy-16|A-methylpregna-1,4-diene-3,20-dione
21-Acetoxyfluocortolone
Fluocortolone Acetate

Chemical & Physical Properties

[ Density]:
1.12g/cm3

[ Boiling Point ]:
449.3ºC at 760mmHg

[ Molecular Formula ]:
C21H29FO2

[ Molecular Weight ]:
332.45200

[ Flash Point ]:
169.7ºC

[ Exact Mass ]:
332.21500

[ PSA ]:
34.14000

[ LogP ]:
4.67150

[ Vapour Pressure ]:
2.9E-08mmHg at 25°C

[ Index of Refraction ]:
1.53

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
TU5023400
CHEMICAL NAME :
Pregn-4-ene-3,20-dione, 6-alpha-fluoro-
CAS REGISTRY NUMBER :
2300-03-0
BEILSTEIN REFERENCE NO. :
3218997
LAST UPDATED :
199612
DATA ITEMS CITED :
1
MOLECULAR FORMULA :
C21-H29-F-O2
MOLECULAR WEIGHT :
332.50

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Subcutaneous
DOSE :
400 ug/kg
SEX/DURATION :
female 1 day(s) pre-mating
TOXIC EFFECTS :
Reproductive - Maternal Effects - uterus, cervix, vagina
REFERENCE :
85GRAA "The Control of Fertility," Pincus, G., New York, Academic Press, 1965 Volume(issue)/page/year: -,150,1965

Related Compounds

  • Pregn-4-ene-3,20-dione,6-fluoro-11,17,21-trihydroxy-, (6a,11b)-
  • Pregn-4-ene-3,20-dione,6-fluoro-17,21-dihydroxy-16-methyl-, (6a,16a)- (9CI)
  • Pregn-4-ene-3,20-dione,6-fluoro-14,17,21-trihydroxy-16-methyl-, (6a,16a)- (9CI)
  • 6-fluoroprogesterone
  • Pregn-4-ene-3,20-dione,21-(acetyloxy)-6-fluoro-16,17-[(1-methylethylidene)bis(oxy)]-, (6a,16a)- (9CI)
  • Pregn-4-ene-3,20-dione,21-(acetyloxy)-6-fluoro-11,17-dihydroxy-, (6a,11b)- (9CI)
  • Ethyl 4-(2-((5-((4-fluorobenzamido)methyl)-1,3,4-oxadiazol-2-yl)thio)acetyl)piperazine-1-carboxylate
  • 3-Amino-4-[(3-methyl-2,5-dioxoimidazolidin-1-yl)methyl]benzamide
  • N-(2-Amino-4-methylphenyl)-3-methyl-2,5-dioxo-1-imidazolidineacetamide
  • 2-benzoxy-N-methyl-N-(4-aminophenyl)acetamide
  • N-(5-Amino-2-chlorophenyl)-2-ethoxyacetamide
  • N-(2-amino-6-methylphenyl)-2-(2,4-difluorophenoxy)acetamide
  • N-(5-amino-2-chlorophenyl)-2-(3-fluorophenoxy)acetamide
  • N-(3-amino-4-methylphenyl)-2-(3-fluorophenoxy)acetamide
  • 5-(Chloromethyl)-3-(3,4-difluorophenyl)-1,2,4-oxadiazole
  • 6-(3,4'-dihydroxy-4,4,7,8a-tetramethyl-6'-oxospiro[2,3,4a,5,6,7-hexahydro-1H-naphthalene-8,2'-3,8-dihydrofuro[2,3-e]isoindole]-7'-yl)-2-(2,3,4'-trihydroxy-4,4,7,8a-tetramethyl-6'-oxospiro[2,3,4a,5,6,7-hexahydro-1H-naphthalene-8,2'-3,8-dihydrofuro[2,3-e]isoindole]-7'-yl)hexanoic acid
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