corilagin

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Names

[ CAS No. ]:
23094-69-1

[ Name ]:
corilagin

[Synonym ]:
Benzoic acid, 3,4,5-trihydroxy-, (8R,10S,11R,12S,19R)-5,7,8,11,12,14-hexahydro-1,2,3,11,16,17,18,19-octahydroxy-5,14-dioxo-8,12-methano-10H-dibenzo[j,l][1,4,8]trioxacyclotetradecin-10-yl ester
(1S,19R,21S,22R,23R)-6,7,8,11,12,13,22,23-Octahydroxy-3,16-dioxo-2,17,20-trioxatetracyclo[17.3.1.0.0]tricosa-4,6,8,10,12,14-hexaen-21-yl 3,4,5-trihydroxybenzoate
corilagin
1-O-Galloyl-3,6-hexahydroxydiphenol-b-D-Glucopyranose
1-O-Galloyl-3,6-hexahydroxydiphenol--D-Glucopyranose

Chemical & Physical Properties

[ Density]:
2.1±0.1 g/cm3

[ Boiling Point ]:
1280.8±65.0 °C at 760 mmHg

[ Melting Point ]:
>200ºC dec

[ Molecular Formula ]:
C27H22O18

[ Molecular Weight ]:
634.453

[ Flash Point ]:
418.8±27.8 °C

[ Exact Mass ]:
634.080627

[ PSA ]:
310.66000

[ LogP ]:
2.34

[ Vapour Pressure ]:
0.0±0.3 mmHg at 25°C

[ Index of Refraction ]:
1.881

[ Storage condition ]:
-20°C Freezer

[ Water Solubility ]:
H2O: soluble1mg/mL, clear, colorless

MSDS

Safety Information

[ RIDADR ]:
NONH for all modes of transport

Synthetic Route

Precursor & DownStream

Precursor

  • ac1l4jhe
  • mecysteine
  • Geraniin
  • 1-O-galloyl-3,6-(R)-hexahydroxydiphenoyl-4-O-brevifolincarboxyl-β-D-glucopyranose
  • 1-O-galloyl-2,4,3,6-bis-(R)-4,5,6,4,5,6-hexahydroxydiphenoyl-β-D-glucose

DownStream

  • 1,1-DIPHENYL-2-PICRYLHYDRAZINE

Articles

Mechanisms of action of corilagin and tellimagrandin I that remarkably potentiate the activity of beta-lactams against methicillin-resistant Staphylococcus aureus.

Microbiol. Immunol. 48(1) , 67-73, (2004)

Corilagin and tellimagrandin I are polyphenols isolated from the extract of Arctostaphylos uvaursi and Rosa canina L. (rose red), respectively. We have reported that corilagin and tellimagrandin I rem...

Inhibitory effect of the gallotannin corilagin on dextran sulfate sodium-induced murine ulcerative colitis.

J. Nat. Prod. 76(11) , 2120-5, (2013)

The therapeutic effect of corilagin (1) was evaluated in an acute colitis model induced by dextran sulfate sodium (DSS) in mice, and the mechanism of action was investigated in this study. Animals wer...

Modulation of PAI-1 and tPA activity and thrombolytic effects of corilagin.

Planta Med. 69(12) , 1109-12, (2003)

In this study, Charlton's and Tomihisa's methods were modified to investigate the thrombolytic effect of corilagin from the Chinese herbal plant Phyllanthus urinaria L., as well as its effect on carot...


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