N,N-diethyl-2-chloroacetamide

Suppliers

Names

[ Name ]:
N,N-diethyl-2-chloroacetamide

[Synonym ]:
CDEA
tl83
N-diethylacetaMide
MONOMETHYLFORMAMIDE TECH
EINECS 219-019-2
MFCD00000928
Acetamide, 2-chloro-N,N-diethyl-
α-Chloro-N,N-diethylacetamide
2-Chloro-N
diethyl 2-chloroacetamide
N-Chloroacetyldiethylamine
N,N-Diethyl-2-chloro
N,N-diethyl chloroacetamide
CHLOROACETYLDIETHYLAMINE
N,N-Diethylchloroacetamide
2-chloro-N,N-diethyl-acetamide
2-Chloro-N,N-diethylacetamide
N,N-diethyl-2-chloroacetamide
N,N,-Diethylchloroacetamide

Chemical & Physical Properties

[ Density]:
1.0±0.1 g/cm3

[ Boiling Point ]:
236.8±0.0 °C at 760 mmHg

[ Molecular Formula ]:
C₆H₁₂ClNO

[ Molecular Weight ]:
149.619

[ Flash Point ]:
77.0±22.6 °C

[ Exact Mass ]:
149.060745

[ PSA ]:
20.31000

[ LogP ]:
0.55

[ Vapour Pressure ]:
0.0±0.4 mmHg at 25°C

[ Index of Refraction ]:
1.449

[ Water Solubility ]:
soluble

MSDS

Click to get detail MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: AB5425000

CHEMICAL NAME :: Acetamide, 2-chloro-N,N-diethyl-

CAS REGISTRY NUMBER :: 2315-36-8

BEILSTEIN REFERENCE NO. :: 0605866

LAST UPDATED :: 199701

DATA ITEMS CITED :: 7

MOLECULAR FORMULA :: C6-H12-Cl-N-O

MOLECULAR WEIGHT :: 149.64

WISWESSER LINE NOTATION :: G1VN2&2

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 500 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: RREVAH Residue Reviews. (Springer-Verlag New York, Inc., Service Center, 44 Hartz Way, Secaucus, NJ 07094) V.1- 1962- Volume(issue)/page/year: 10,97,1965

TYPE OF TEST :: LC50 - Lethal concentration, 50 percent kill

ROUTE OF EXPOSURE :: Inhalation

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 315 mg/m3/4H

TOXIC EFFECTS :: Behavioral - excitement Behavioral - muscle weakness Lungs, Thorax, or Respiration - other changes

REFERENCE :: GTPZAB Gigiena Truda i Professional'nye Zabolevaniya. Labor Hygiene and Occupational Diseases. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1-36, 1957-1992. For publisher information, see MTPEEI Volume(issue)/page/year: 35(6),36,1991

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Administration onto the skin

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 980 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: GTPZAB Gigiena Truda i Professional'nye Zabolevaniya. Labor Hygiene and Occupational Diseases. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1-36, 1957-1992. For publisher information, see MTPEEI Volume(issue)/page/year: 33(2),51,1989

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 226 mg/kg

TOXIC EFFECTS :: Behavioral - excitement Behavioral - muscle weakness Lungs, Thorax, or Respiration - other changes

REFERENCE :: GTPZAB Gigiena Truda i Professional'nye Zabolevaniya. Labor Hygiene and Occupational Diseases. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1-36, 1957-1992. For publisher information, see MTPEEI Volume(issue)/page/year: 35(6),36,1991

TYPE OF TEST :: LC50 - Lethal concentration, 50 percent kill

ROUTE OF EXPOSURE :: Inhalation

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 270 mg/m3/2H

TOXIC EFFECTS :: Behavioral - excitement Behavioral - muscle weakness Lungs, Thorax, or Respiration - other changes

REFERENCE :: GTPZAB Gigiena Truda i Professional'nye Zabolevaniya. Labor Hygiene and Occupational Diseases. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1-36, 1957-1992. For publisher information, see MTPEEI Volume(issue)/page/year: 35(6),36,1991

TYPE OF TEST :: LC50 - Lethal concentration, 50 percent kill

ROUTE OF EXPOSURE :: Inhalation

SPECIES OBSERVED :: Rodent - guinea pig

DOSE/DURATION :: 175 mg/m3/4H

TOXIC EFFECTS :: Behavioral - excitement Behavioral - muscle weakness Lungs, Thorax, or Respiration - other changes

REFERENCE :: GTPZAB Gigiena Truda i Professional'nye Zabolevaniya. Labor Hygiene and Occupational Diseases. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1-36, 1957-1992. For publisher information, see MTPEEI Volume(issue)/page/year: 35(6),36,1991

Safety Information

[ Symbol ]:

GHS06

[ Signal Word ]:
Danger

[ Hazard Statements ]:
H302-H311-H315-H319-H330-H335

[ Precautionary Statements ]:
P260-P280-P284-P305 + P351 + P338-P310

[ Personal Protective Equipment ]:
Eyeshields;Faceshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter

[ Hazard Codes ]:
T+:Verytoxic;

[ Risk Phrases ]:
R21/22;R26;R36/37/38

[ Safety Phrases ]:
S45-S38-S36/37/39-S28A-S26-S28

[ RIDADR ]:
2810

[ RTECS ]:
AB5425000

[ Packaging Group ]:
III

[ Hazard Class ]:
6.1

[ HS Code ]:
29241900

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

Diethylamine
Chloroacetyl chloride
Chloroacetic acid
Bromoacetyl chloride
Acetamide,2-chloro-N-(2-chloroacetyl)-
ETHENAMINE, 1,2,2-TRICHLORO-N,N-DIETHYL-
2-diethylamino-4,5-dimethyl-2,2-dipropoxy-2λ5-[1,3,2]dioxaphosphole
Chloroacetic anhydride
diethyl-(1,2-dichloro-vinyl)-amine

DownStream

2-[[2-(diethylamino)-2-oxoethyl]-(2-hydroxyethyl)amino]-N,N-diethylacetamide
2-HYDROXY-N,N-DIETHYLACETAMIDE
N,N-diethyl-2-(4-methylanilino)acetamide
coumarin, 3-chloro-
6,12-Epoxy-6H,12H-dibenzo[b,f][1,5]dioxocin
2-[[4-Allyl-2-(N,N-dimethylaminomethyl)-6-methoxyphenyl]oxy]-N,N-diethylacetamide
4,4,4-trichloro-N,N-diethyl-3-hydroxybutanamide
3CAI
3(2H)-Thiazoleacetamide,N,N-diethyl-2-[(2-furanylcarbonyl)imino]-5-nitro-
2-(diethylamino)-N,N-diethylacetamide

Customs

[ HS Code ]: 2924199090

[ Summary ]:
2924199090. other acyclic amides (including acyclic carbamates) and their derivatives; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

Articles

Fluoride-selective binding in a new deep cavity calix[4]pyrrole: experiment and theory.

J. Am. Chem. Soc. 124(29) , 8644-52, (2002)

A new "super-extended cavity" tetraacetylcalix[4]pyrrole derivative was synthesized and characterized, and X-ray crystal structures of complexes bound to fluoride and acetonitrile were obtained. The b...

[Gas-chromatographic analysis of N,N-diethylchloracetamide in the air].

Gig. Sanit. (5) , 57-9, (1989)

[Local and skin resorptive action of N,N-diethylchloracetamide].

Gig. Tr. Prof. Zabol. (2) , 51-2, (1989)

N,N-diethyl-2-[2-[methyl(diphenyl)silyl]ethoxy]ethanamine
N,N-diethyl-(2,6,6-trimethyl-1-cyclohexenyl)methanamine N-oxide
N,N-diethyl-2-phenylethynesulfonamide
N,N-diethyl-2-methylcyclohexa-2,5-dien-1-amine
N,N-diethyl-2-(trifluoromethyl)cyclohexa-2,4-dien-1-amine
N,N-diethyl-2-[1-ethylsulfanyl-3-(2-methylphenoxy)propan-2-yl]oxy-ethanamine; 2-hydroxypropane-1,2,3-tricarboxylic acid
1-[9-(5-Methoxy-3-pyridinyl)-3,9-diazabicyclo[4.2.1]non-3-yl]ethanone
(E)-3-(1-((4-((dimethylamino)methyl)phenyl)sulfonyl)-1H-pyrrol-3-yl)-N-hydroxyacrylamide
Tert-butyl ((1-(thiophene-3-carbonyl)piperidin-2-yl)methyl)carbamate
N-Boc-(+/-)-amino-4-methoxyphenylbutanal
2-amino-5-methyl-2,3-dihydro-1H-imidazo[5,1-f][1,2,4]triazin-4-one
5-(2-Thienyl)-3,4,4a,5,6,10b-hexahydro-2H-pyrano[3,2-c]quinoline
tert-butyl N-[1-amino-3-(oxan-2-yl)propan-2-yl]carbamate
4-(((Benzyloxy)carbonyl)amino)-1-(tert-butoxycarbonyl)pyrrolidine-2-carboxylic acid
3-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)-4-hydroxycyclopentane-1-carboxylic acid
Tert-butyl 3-butanoylpiperidine-1-carboxylate

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