H-Glu(OMe)-OMe.HCl

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Names

[ CAS No. ]:
23150-65-4

[ Name ]:
H-Glu(OMe)-OMe.HCl

[Synonym ]:
dimethyl DL-glutamate hydrochloride
L-Glutamic acid, dimethyl ester, hydrochloride (1:1)
H-Glu(OMe)-OMe��HCl
H-Glu(OMe)-OMe·HCl
H-Glu(OMe)-OMe.HCl
H-Glu(OMe)-OMe,HCl
(S)-Dimethyl 2-aminopentanedioate hydrochloride
L-Glutamicaciddimethylesterhydrochloride
MFCD00038879
DiMethyl L-GlutaMate Hydrochloride
L-Glutamic acid dimethyl ester hydrochloride
Dimethyl L-glutamate hydrochloride (1:1)
EINECS 245-461-0

Chemical & Physical Properties

[ Density]:
1.129g/cm3

[ Boiling Point ]:
224.3ºC at 760 mmHg

[ Melting Point ]:
89-90°C

[ Molecular Formula ]:
C7H14ClNO4

[ Molecular Weight ]:
211.643

[ Flash Point ]:
76.7ºC

[ Exact Mass ]:
211.061142

[ PSA ]:
78.62000

[ LogP ]:
0.94220

[ Vapour Pressure ]:
0.0919mmHg at 25°C

[ Index of Refraction ]:
26 ° (C=5, H2O)

MSDS

Click to get detail MSDS

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ Safety Phrases ]:
S22-S24/25

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

[ HS Code ]:
2922499990

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • Methanol
  • L-glutamic acid
  • Chlorotrimethylsilane
  • Lascivol
  • L-Glutamic acid:Hcl (17O4)
  • H-Glu(OMe)-OH
  • 2,2-Dimethoxypropane
  • DL-Glutamic acid

DownStream

  • N-(4-aminobenzoyl)-L-glutamic acid
  • Methyl L-Pyroglutamate
  • METHYL(2S)-2-(BIS(TERT-BUTOXYCARBONYL)AMINO)-5-OXOPENTANOATE
  • L-glutamic acid
  • DIMETHYL 2-(1H-PYRROL-1-YL)PENTANEDIOATE
  • Dimethyl Glutamate
  • Boc-Glu(Ome)-OMe
  • (S)-TERT-BUTYL (1,5-DIHYDROXYPENTAN-2-YL)CARBAMATE
  • dimethyl (2S)-2-(benzylamino)pentanedioate
  • H-Lys-Glu-OH

Preparation


Customs

[ HS Code ]: 2922499990

[ Summary ]:
HS:2922499990 other amino-acids, other than those containing more than one kind of oxygen function, and their esters; salts thereof VAT:17.0% Tax rebate rate:9.0% Supervision conditions:AB(certificate of inspection for goods inward,certificate of inspection for goods outward) MFN tariff:6.5% General tariff:30.0%

Articles

Effects of the methyl esters of pyruvate, succinate and glutamate on the secretory response to meglitinide analogues in rat pancreatic islets.

Pharmacol. Res. 33(3) , 191-4, (1996)

The insulinotropic action of the meglitinide analogues KAD-1229, A-4166 and repaglinide was examined in rat pancreatic islets deprived of exogenous nutrient or incubated in the presence of nutrient se...

Potentiation and prolongation of the insulinotropic action of glucagon-like peptide 1 by methyl pyruvate or dimethyl ester of L-glutamic acid in a type 2 diabetes animal model.

Endocrine 16(2) , 113-6, (2001)

Methyl pyruvate and the dimethyl ester of L-glutamic acid were administered intravenously, as a primed constant infusion (1.0-2.0 micromol followed by 0.5-1.0 micromol/min, both expressed per gram of ...

Spectrum of toxicities of amino acid methyl esters for myeloid cells is determined by distinct metabolic pathways.

Blood 79(4) , 964-71, (1992)

L-leucine methyl ester (Leu-OMe), Leu-Leu-OMe, Phe-OMe, and Glu-(OMe)2 are toxic to mononuclear phagocytes (M phi) and neutrophils. In the present studies, the mechanism of this toxicity was examined....


More Articles

Related Compounds

  • H-Glu(OMe)-OMe.HCl
  • H-Glu(OMe)-OtBu
  • H-GLU(OME)-NH2 HCL
  • H-GLU-OME
  • H-Glu-Ome
  • H-Glu(OMe)-OH
  • 1,3-dioxo-2,3-dihydro-1H-isoindol-2-yl 1-methyl-3-(pyridin-4-yl)-1H-pyrazole-4-carboxylate
  • 1,3-dioxo-2,3-dihydro-1H-isoindol-2-yl 5-methyl-1-phenyl-1H-1,2,3-triazole-4-carboxylate
  • 1,3-dioxo-2,3-dihydro-1H-isoindol-2-yl 2,6-difluoro-3-methanesulfonylbenzoate
  • 1,3-dioxo-2,3-dihydro-1H-isoindol-2-yl 3-(4-methanesulfonylphenyl)propanoate
  • 1,3-dioxo-2,3-dihydro-1H-isoindol-2-yl 3-methanesulfonyl-4-methoxybenzoate
  • 1,3-dioxo-2,3-dihydro-1H-isoindol-2-yl 2-(2-fluorophenyl)-1,3-thiazole-4-carboxylate
  • 1,3-dioxo-2,3-dihydro-1H-isoindol-2-yl 2-benzyl-1,3-thiazole-4-carboxylate
  • 1,3-dioxo-2,3-dihydro-1H-isoindol-2-yl 1-methyl-3-oxo-1,2,3,4-tetrahydroquinoxaline-6-carboxylate
  • 1,3-dioxo-2,3-dihydro-1H-isoindol-2-yl 2-methoxyquinoline-4-carboxylate
  • 1,3-dioxo-2,3-dihydro-1H-isoindol-2-yl 3,4,7-trimethyl-1-benzofuran-2-carboxylate
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