3-PHTHALODINITRILE

Names

[ CAS No. ]:
2317-22-8

[ Name ]:
3-PHTHALODINITRILE

[Synonym ]:
2-methylisophthalonitrile
cyano-o-tolunitrile
MFCD00012285
methylisophthalonitrile
2,6-Dicyanotoluene

Chemical & Physical Properties

[ Density]:
1.12g/cm3

[ Boiling Point ]:
125-130ºC2 mm Hg(lit.)

[ Melting Point ]:
135-137ºC(lit.)

[ Molecular Formula ]:
C₉H₆N₂

[ Molecular Weight ]:
142.15700

[ Flash Point ]:
117.2ºC

[ Exact Mass ]:
142.05300

[ PSA ]:
47.58000

[ LogP ]:
1.73836

[ Vapour Pressure ]:
0.00113mmHg at 25°C

[ Index of Refraction ]:
1.555

MSDS

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H302 + H312 + H332-H315-H319-H335

[ Precautionary Statements ]:
P261-P280-P305 + P351 + P338

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves

[ Hazard Codes ]:
Xn: Harmful;

[ Risk Phrases ]:
20/21/22-36/37/38

[ Safety Phrases ]:
26-36

[ RIDADR ]:
NONH for all modes of transport

[ HS Code ]:
2926909090

Customs

[ HS Code ]: 2926909090

[ Summary ]:
HS:2926909090 other nitrile-function compounds VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:30.0%

Articles

Synthesis of 3-substituted benzamides and 5-substituted isoquinolin-1(2H)-ones and preliminary evaluation as inhibitors of poly(ADP-ribose)polymerase (PARP).

Bioorg. Med. Chem. 6(6) , 721-34, (1998)

Inhibitors of poly(ADP-ribose)polymerase (PARP) inhibit repair of damaged DNA and thus potentiate radiotherapy and chemotherapy of cancer. 3-Substituted benzamides and 5-substituted isoquinolin-1-ones...

2,5-dimethyl-1,3-phthalodinitrile
3(2,4 DIMETHYL PENTALOXY PHTHALODINITRILE)
3-[(4-chloro-3-methyl-phenoxy)methyl]-5-(4-fluorophenyl)-4-(4-methylph enyl)-1,2,4-triazole
3-[[2-(2-chloro-4-nitro-phenoxy)acetyl]amino]-4-methoxy-benzenesulfonyl fluoride
3-isothiocyanatopropanoyl chloride
3-(4-amino-2-cyanoimino-5,6-dihydropyrimidin-1-yl)propanenitrile