Fluorescein

Suppliers

Names

[ CAS No. ]:
2321-07-5

[ Name ]:
Fluorescein

[Synonym ]:
D and C Yellow No. 7
D&C Yellow No. 7
D+C Yellow No. 7
Fluorescein (free acid)
3',6'-Dihydroxyspiro[isobenzofuran-1(3H),9'-[9H]xanthen]-3-one
3',6'-Fluorandiol
Fluorecein
Eosin
YELLOW 7
3',6'-Dihydroxy-3H-spiro[isobenzofuran-1,9'-xanthen]-3-one
KI201
MFCD00005050
Acid Yellow 73
3',6'-Dihydroxy-3H-spiro[2-benzofuran-1,9'-xanthen]-3-one
Fluorescite
EINECS 219-031-8
Uranine Yellow
C.I. Acid Yellow 73
angiofluor
Soluble fluorescein
D & C Yellow no. 7
Fluor-I-Strip
D & C Yellow no. 8
Spiro[isobenzofuran-1(3H),9'-[9H]xanthen]-3-one, 3',6'-dihydroxy-
Fluorescein
Ful-Glo
Funduscein

Chemical & Physical Properties

[ Density]:
1.6±0.1 g/cm3

[ Boiling Point ]:
620.8±55.0 °C at 760 mmHg

[ Melting Point ]:
320 °C(lit.)

[ Molecular Formula ]:
C20H12O5

[ Molecular Weight ]:
332.306

[ Flash Point ]:
232.6±25.0 °C

[ Exact Mass ]:
332.068481

[ PSA ]:
87.74000

[ LogP ]:
2.98

[ Vapour Pressure ]:
0.0±1.9 mmHg at 25°C

[ Index of Refraction ]:
1.792

[ Storage condition ]:
−20°C

[ Water Solubility ]:
insoluble

MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
LM5075000
CHEMICAL NAME :
Fluorescein
CAS REGISTRY NUMBER :
2321-07-5
BEILSTEIN REFERENCE NO. :
0094324
LAST UPDATED :
199707
DATA ITEMS CITED :
10
MOLECULAR FORMULA :
C20-H12-O5
MOLECULAR WEIGHT :
332.32
WISWESSER LINE NOTATION :
T C666 BO EVJ IR BVQ& MQ

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
600 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
300 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE :
Unreported
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
600 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Rodent - rabbit
DOSE/DURATION :
300 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE :
Unreported
SPECIES OBSERVED :
Rodent - guinea pig
DOSE/DURATION :
400 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value

MUTATION DATA

TYPE OF TEST :
DNA adduct
TEST SYSTEM :
Bacteria - Escherichia coli
DOSE/DURATION :
15 umol/L
REFERENCE :
MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 89,95,1981 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - 33350 No. of Facilities: 495 (estimated) No. of Industries: 18 No. of Occupations: 21 No. of Employees: 5188 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - 33350 No. of Facilities: 2171 (estimated) No. of Industries: 42 No. of Occupations: 55 No. of Employees: 88495 (estimated) No. of Female Employees: 21558 (estimated)

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H319

[ Precautionary Statements ]:
P305 + P351 + P338

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ Hazard Codes ]:
Xi:Irritant;

[ Risk Phrases ]:
R36;R43

[ Safety Phrases ]:
S22-S24/25-S37/39-S26

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

[ RTECS ]:
LM5075000

[ Packaging Group ]:
I; II; III

[ HS Code ]:
3204200000

Synthetic Route

Precursor & DownStream

Precursor

  • Fluorescein Diacetate
  • Phthalic anhydride
  • Resorcine
  • 6-FITC
  • 5-Aminofluorescein
  • Phenol
  • 2,4-Dihydroxyacetophenone
  • FLUORESCEIN MONO-P-GUANIDINOBENZOATE*HYD ROCHLORIDE

DownStream

  • Fluorescein isothiocyanate
  • 3',6'-DIMETHOXYFLUORAN
  • 2',4',5'-trichloro-fluorescein
  • 2',4',5',7'-tetrachlorofluorescein
  • 4',5'-DINITROFLUORESCEIN
  • Spiroisobenzofuran-1(3H),9-9Hxanthen-3-one, 2,4,5-tribromo-3,6-dihydroxy-
  • 2-(2,4-Dihydroxybenzoyl)benzoic acid
  • Resorcine
  • benzoic acid

Customs

[ HS Code ]: 2932999099

[ Summary ]:
2932999099. other heterocyclic compounds with oxygen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

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Related Compounds

  • FLUORESCEIN
  • fluorescein
  • fluorescein
  • Fluorescein
  • Fluorescein EB
  • 5MP-Fluorescein
  • N-(5-Acetyl-4-chloro-2-pyridinyl)cyclopropanecarboxamide
  • 2-Hydroxy-5-(naphthalen-1-YL)isophthalaldehyde
  • Ethyl 1-(cyclobutylmethyl)-1H-imidazole-4-carboxylate
  • 1-(3-(Trifluoromethyl)quinoxalin-6-yl)ethan-1-ol
  • (R)-1-(5-Bromo-4-chlorothiophen-2-yl)ethan-1-amine hydrochloride
  • 1-(2-(Trifluoromethyl)quinoxalin-6-yl)ethan-1-one
  • 2-Amino-6,7-dihydro-5H-pyrrolo[2,3-b]pyrazin-7-ol
  • Methyl 2-(tert-butyl)-5-methylnicotinate
  • 4,5-Bis((4S,5R)-4,5-diphenyl-4,5-dihydrooxazol-2-yl)acridine
  • (3aR,8aS)-2-(2'-(Diphenylphosphanyl)-[1,1'-biphenyl]-2-yl)-3a,8a-dihydro-8H-indeno[1,2-d]oxazole
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