(2S)-2-Amino-4-pentynoic acid

Suppliers

Names

[ Name ]:
(2S)-2-Amino-4-pentynoic acid

[Synonym ]:
(S)-alpha-Propargylglycine
(S)-2-Aminopent-4-ynoic acid
(2S)-2-Amino-4-pentynoic acid
L-C-Propargylglycine
MFCD00077855
L-propargyl glycine
(2S)-2-aminopent-4-ynoic acid
4-Pentynoic acid, 2-amino-, (2S)-

Chemical & Physical Properties

[ Density]:
1.2±0.1 g/cm3

[ Boiling Point ]:
272.1±35.0 °C at 760 mmHg

[ Melting Point ]:
232ºC

[ Molecular Formula ]:
C₅H₇NO₂

[ Molecular Weight ]:
113.115

[ Flash Point ]:
118.3±25.9 °C

[ Exact Mass ]:
113.047676

[ PSA ]:
63.32000

[ LogP ]:
-0.03

[ Vapour Pressure ]:
0.0±1.2 mmHg at 25°C

[ Index of Refraction ]:
1.513

[ Storage condition ]:
2-8°C

MSDS

Click to get detail MSDS

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ Hazard Codes ]:
Xi

[ Safety Phrases ]:
22-24/25

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

[ HS Code ]:
2922499990

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

Ac-propargylglycine
N-Chloroacetyl-D-α-propargylglycine
N-Methoxyacetyl-D-α-propargylglycine
diethyl 2-acetamido-2-prop-1-ynylpropanedioate
ethyl 2-acetamidopent-4-ynoate
2-acetamido-2-ethoxycarbonylpent-3-ynoate
2'-hydroxy-[1,1'-binaphthalen]-2-yl 2-((diphenylmethylene)amino)pent-4-ynoate

DownStream

Customs

[ HS Code ]: 2922499990

[ Summary ]:
HS:2922499990 other amino-acids, other than those containing more than one kind of oxygen function, and their esters; salts thereof VAT:17.0% Tax rebate rate:9.0% Supervision conditions:AB(certificate of inspection for goods inward,certificate of inspection for goods outward) MFN tariff:6.5% General tariff:30.0%

Articles

[Hydrogen sulfide inhibits Ca(2+)-induced mitochondrial permeability transition pore opening in spontaneously hypertensive rats].

Fiziol. Zh. 59(1) , 3-10, (2013)

In experiments in vivo and in vitro on the mitochondria isolated from the control and spontaneously hypertensive rats (SHR) hearts, we studied the effects of a donor of hydrogen sulfide (H2S), NaHS, a...

Inhibition of cystathionine gamma-lyase and the biosynthesis of endogenous hydrogen sulphide ameliorates gentamicin-induced nephrotoxicity

Eur. J. Pharmacol. 685(1-3) , 165-73, (2012)

Clinical use of gentamicin over prolonged periods is limited because of dose- and time-dependent nephrotoxicity. Primarily, lysosomal phospholipidosis, intracellular oxidative stress and heightened in...

Interdependency of cystathione γ-lyase and cystathione β-synthase in hydrogen sulfide-induced blood pressure regulation in rats.

Am. J. Hypertens. 25 , 74-81, (2012)

Hydrogen sulfide (H(2)S), an endogenous vasoactive agent, is produced by cystathionine γ-lyase (CGL) and cystathionine β-synthase (CBS) enzymes. This study was conducted to evaluate the relative contr...

(R)-2-amino-4-pentynoic acid amide
(S)-2-Amino-4-pentynoic acid t-butyl ester
Fmoc-L-propargylglycine
(S)-N-Boc-Propargylglycine
(S)-Methyl 2-((tert-butoxycarbonyl)amino)pent-4-ynoate
Fmoc-D-Pra-OH
4-(Tert-butoxycarbonylamino)-2-ethylcyclopentanecarboxylic acid
N-(2,4-dichlorophenyl)-2-(6-oxo-3-phenylpyridazin-1(6H)-yl)acetamide
N-[4-(benzylcarbamoyl)phenyl]-4-phenylpiperazine-1-carboxamide
N-cyclohexyl-3-[6-(3,5-dimethyl-1H-pyrazol-1-yl)[1,2,4]triazolo[4,3-b]pyridazin-3-yl]propanamide
2,2-dimethyl-N-[2-(pyridin-3-yl)-1H-benzimidazol-5-yl]propanamide
2-{2-[4-(2-methoxyphenyl)piperazino]-2-oxoethyl}-6-(2-thienyl)-3(2H)-pyridazinone
2-(5-bromo-1H-indol-1-yl)-N-[(2E)-5-(methoxymethyl)-1,3,4-thiadiazol-2(3H)-ylidene]acetamide
2-[6-oxo-3-(thiomorpholin-4-yl)pyridazin-1(6H)-yl]-N-[(2E)-5-(propan-2-yl)-1,3,4-thiadiazol-2(3H)-ylidene]acetamide
2-[3-(2-chlorophenyl)-6-oxopyridazin-1(6H)-yl]-N-[(2E)-5-(tetrahydrofuran-2-yl)-1,3,4-thiadiazol-2(3H)-ylidene]acetamide
3-[6-(3,5-dimethyl-1H-pyrazol-1-yl)[1,2,4]triazolo[4,3-b]pyridazin-3-yl]-N-[(2Z)-4-methyl-1,3-thiazol-2(3H)-ylidene]propanamide

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