(r)-(-)-1,2,3,4-tetrahydro-1-naphthol

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Names

[ CAS No. ]:
23357-45-1

[ Name ]:
(r)-(-)-1,2,3,4-tetrahydro-1-naphthol

[Synonym ]:
(R)-(-)-α-Tetralol
(R)-(-)-1,2,3,4-Tetrahydro-1-naphthol
(R)-Tetralin-1-ol
24-Tetrahydro-1-naphthol
MFCD00063005
(R)-Tetralol
(-)-1-Naphthalenol
(R)-1-Tetralol
(R)-1,2,3,4-tetrahydro-naphthalen-1-ol
(R)-1,2,3,4-Tetrahydronaphthalen-1-ol

Chemical & Physical Properties

[ Density]:
1.09 g/mL at 25 °C(lit.)

[ Boiling Point ]:
140 °C17 mm Hg(lit.)

[ Melting Point ]:
37-39 °C

[ Molecular Formula ]:
C10H12O

[ Molecular Weight ]:
148.20200

[ Flash Point ]:
>230 °F

[ Exact Mass ]:
148.08900

[ PSA ]:
20.23000

[ LogP ]:
2.05630

[ Vapour Pressure ]:
0.00874mmHg at 25°C

[ Index of Refraction ]:
1.584

[ Storage condition ]:
0-10°C

MSDS

Click to get detail MSDS

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H315-H319-H335

[ Precautionary Statements ]:
P261-P305 + P351 + P338

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves

[ Hazard Codes ]:
Xi: Irritant;

[ Risk Phrases ]:
36/37/38

[ Safety Phrases ]:
S26-S36

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • 3,4-Dihydronaphthalen-1(2H)-one
  • dihydronaphthalene
  • 1,2,3,4-tetrahydronaphthalen-1-yl acetate
  • UNII:87652943HP
  • 1,2,3,4-Tetrahydronaphthalene
  • acetic acid,1,2,3,4-tetrahydronaphthalen-1-ol
  • (R)-O-((4aS-(2α,4aα,5α,8α,8aα))-Octahydro-8,9,9-trimethyl-5,8-methano-2H-1-benzopyran-2-yl)-1-tetralol
  • Acetanisole
  • Dimethylphenylsilane

DownStream

  • 3,4-Dihydronaphthalen-1(2H)-one
  • UNII:87652943HP
  • (1S)-1,2,3,4-Tetrahydro-1-naphthalenamine
  • 1-chloro-1,2,3,4-tetrahydronaphthalene

Preparation


Articles

Stereochemical sensitivity of the human UDP-glucuronosyltransferases 2B7 and 2B17.

J. Med. Chem. 49 , 1818-27, (2006)

A set of 28 enantiomers comprising rigid and flexible secondary alcohols was synthesized by the asymmetric Corey-Bakshi-Shibata reduction. The enantiomerically pure alcohols were subjected to enzymati...


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Related Compounds

  • (R)-(-)-1,2,3,4-tetrahydro-1-naphthol
  • (R)-1,2,3,4-tetrahydro-1-naphthylamine hydrogen L-tartrate
  • (R)-1,2,3,4-TETRAHYDRO-1-NAPHTHYLAMINE
  • (R)-1,2,3,4-Tetrahydro-1-methyl-6,7-isoquinolinediol
  • (S)-(+)-1,2,3,4-Tetrahydro-1-naphthol
  • 5-METHOXY-1,2,3,4-TETRAHYDRO-1-NAPHTHOL