CGP77675

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Names

[ CAS No. ]:
234772-64-6

[ Name ]:
CGP77675

[Synonym ]:
unii-eqh27e0wrv
CGP77675

Chemical & Physical Properties

[ Molecular Formula ]:
C26H29N5O2

[ Molecular Weight ]:
443.54100

[ Exact Mass ]:
443.23200

[ PSA ]:
89.43000

[ LogP ]:
4.19660

[ Appearance of Characters ]:
powder,white to beige

[ Storage condition ]:
2-8°C

[ Water Solubility ]:
DMSO: >10mg/mL

MSDS

Click to get detail MSDS

Safety Information

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

Articles

The integrin antagonist cilengitide activates alphaVbeta3, disrupts VE-cadherin localization at cell junctions and enhances permeability in endothelial cells.

PLoS ONE 4 , e4449, (2009)

Cilengitide is a high-affinity cyclic pentapeptdic alphaV integrin antagonist previously reported to suppress angiogenesis by inducing anoikis of endothelial cells adhering through alphaVbeta3/alphaVb...

Mechanisms involved in PGE2-induced transactivation of the epidermal growth factor receptor in MH1C1 hepatocarcinoma cells.

J. Exp. Clin. Cancer Res 31 , 72, (2013)

It is important to understand the mechanisms by which the cells integrate signals from different receptors. Several lines of evidence implicate epidermal growth factor (EGF) receptor (EGFR) in the pat...


More Articles

Related Compounds

  • 4-((Cyclohexylamino)methyl)benzoic acid hydrochloride
  • 1-[(2,4-Dichlorophenyl)methyl]-N-(1,1-dimethylethyl)-2-methyl-1H-indole-3-methanamine
  • 2-Methoxy-6-(pyrazol-1-yl)-benzonitrile
  • tert-butyl N-[1-(2-amino-1H-imidazol-5-yl)-2,2-dimethylpropyl]carbamate
  • 1H-3-Benzazepin-7-ol, 8-chloro-2,3,4,5-tetrahydro-5-(3-iodophenyl)-3-methyl-, (S)-
  • 5-Amino-3-methyl-4-[(propan-2-yloxy)carbonyl]thiophene-2-carboxylic acid
  • (4-Methyl-tetrahydro-furan-2-yl)-methanol
  • N-(1-cyanocyclopentyl)-2-[4-(4-fluorobenzenesulfonyl)-1,4-diazepan-1-yl]acetamide
  • 4,5,6,7-Tetrahydrobenzo[d]isoxazole-3-carbaldehyde
  • tert-Butyl-DL-alanine