Lawsone methyl ether
Suppliers
Names
[ CAS No. ]:
2348-82-5
[ Name ]:
Lawsone methyl ether
[Synonym ]:
2-Methoxy-p-naphthoquinone
1,4-Naphthalenedione,2-methoxy
2-methoxy-1,4-naphthalenequinone
2-methoxynaphthalene-1,4-dione
2-Methoxy-[1,4]naphthoquinone
2-methoxyl-1,4-naphthoquinone
2-Methoxynaphthoquinone
1,4-NAPHTHOQUINONE,2-METHOXY
MFCD00019539
2-Methoxy-1,4-naphthalenedione
Methoxy-1,4-naphthochinin
Chemical & Physical Properties
[ Density]:
1.28g/cm3
[ Boiling Point ]:
339.8ºC at 760mmHg
[ Melting Point ]:
184-187ºC(lit.)
[ Molecular Formula ]:
C11H8O3
[ Molecular Weight ]:
188.17900
[ Flash Point ]:
152.7ºC
[ Exact Mass ]:
188.04700
[ PSA ]:
43.37000
[ LogP ]:
1.59590
[ Vapour Pressure ]:
8.98E-05mmHg at 25°C
[ Index of Refraction ]:
1.589
[ Storage condition ]:
-20℃
MSDS
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- QL8960000
- CHEMICAL NAME :
- 1,4-Naphthoquinone, 2-methoxy-
- CAS REGISTRY NUMBER :
- 2348-82-5
- LAST UPDATED :
- 199701
- DATA ITEMS CITED :
- 3
- MOLECULAR FORMULA :
- C11-H8-O3
- MOLECULAR WEIGHT :
- 188.19
- WISWESSER LINE NOTATION :
- L66 BV EVJ CO1
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 320 mg/kg
- TOXIC EFFECTS :
- Tumorigenic - active as anti-cancer agent
- REFERENCE :
- JMCMAR Journal of Medicinal Chemistry. (American Chemical Soc., Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC 20037) V.6- 1963- Volume(issue)/page/year: 26,570,1983
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Bird - wild bird species
- DOSE/DURATION :
- 316 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- AECTCV Archives of Environmental Contamination and Toxicology. (Springer-Verlag New York, Inc., Service Center, 44 Hartz Way, Secaucus, NJ 070944) V.1- 1973- Volume(issue)/page/year: 12,355,1983
Safety Information
[ Symbol ]:
GHS07
[ Signal Word ]:
Warning
[ Hazard Statements ]:
H315-H319-H335
[ Precautionary Statements ]:
P261-P305 + P351 + P338
[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves
[ Hazard Codes ]:
Xi: Irritant;
[ Risk Phrases ]:
36/37/38
[ Safety Phrases ]:
S26;S36
[ RIDADR ]:
NONH for all modes of transport
[ RTECS ]:
QL8960000
[ HS Code ]:
2914690090
Synthetic Route
Precursor & DownStream
Precursor
DownStream
Customs
[ HS Code ]: 2914690090
[ Summary ]:
2914690090 other quinones。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:5.5%。General tariff:30.0%
Articles
Life Sci. 135 , 158-64, (2015)
The compound 2-methoxy-1,4-naphthoquinone (MNQ) was previously shown to be cytotoxic against several cancer cell lines, but its mode of action is poorly understood. In this study, we aimed to explore ...
Fitoterapia 83(8) , 1336-44, (2012)
2-Methoxy-1,4-naphthoquinone (MeONQ) from Impatiens balsamina L. exhibited strong anti-H. pylori activity in our previous study. In this study, we investigated the cytotoxicity of MeONQ against gastri...
Arch. Insect Biochem. Physiol. 66(1) , 45-52, (2007)
The effects of the natural compound 2-methoxy-1,4-naphthoquinone, isolated from the leaves of Impatiens glandulifera and the synthetic compounds 2-propoxy-1,4-naphthoquinone and 2-isopropoxy-1,4-napht...