1-(Chloroacetyl)-L-proline

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Names

[ CAS No. ]:
23500-10-9

[ Name ]:
1-(Chloroacetyl)-L-proline

[Synonym ]:
L-Proline, 1-(2-chloroacetyl)-
1-(Chloroacetyl)-L-proline
N-chloroacetyl-L-proline
1-chloroacetyl-L-proline
Anagliptin Impurity 1

Chemical & Physical Properties

[ Density]:
1.4±0.1 g/cm3

[ Boiling Point ]:
399.0±37.0 °C at 760 mmHg

[ Molecular Formula ]:
C7H10ClNO3

[ Molecular Weight ]:
191.612

[ Flash Point ]:
195.1±26.5 °C

[ Exact Mass ]:
191.034927

[ PSA ]:
57.61000

[ LogP ]:
-0.46

[ Vapour Pressure ]:
0.0±2.0 mmHg at 25°C

[ Index of Refraction ]:
1.539

Safety Information

[ HS Code ]:
2933990090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • Chloroacetyl chloride
  • Proline
  • Chloroacetic acid
  • H-DL-PRO-NH2

DownStream

  • 1-(Chloroacetyl)-L-prolinamide
  • Vildagliptin (LAF-237)
  • (2S)-1-(Chloroacetyl)-2-pyrrolidinecarbonitrile
  • H-Gly-Pro-OH

Customs

[ HS Code ]: 2933990090

[ Summary ]:
2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Related Compounds

  • (2'S)-Nicotine 1-Oxide
  • 1-(Chloroacetyl)-L-prolinamide
  • 1-(Chloroacetyl)proline
  • N-chloroacetyl-L-proline ethyl ester
  • chloroacetyl L-proline methyl ester
  • ethyl pyrrolidine-2-carboxylate
  • 6,8-difluoro-N-methyl-3,4-dihydro-2H-1-benzopyran-4-amine hydrochloride
  • Methyl 2-[4-(trifluoromethyl)-1,3-thiazol-5-yl]acetate
  • N-[(5-chloro-2-fluorophenyl)methyl]-N-(4-hydroxypentan-2-yl)prop-2-enamide
  • (2E)-4-(dimethylamino)-N-[2-(6-oxo-1,6-dihydropyridin-3-yl)ethyl]but-2-enamide
  • (2E)-N-[2-(2-chloro-5-hydroxyphenyl)-2-hydroxyethyl]-4-(dimethylamino)-N-methylbut-2-enamide
  • 1-[2-(4-Chlorophenyl)ethenesulfonyl]-2-[(pyrrolidin-1-yl)methyl]pyrrolidine
  • 1-{4-[4-(4-Methyl-1,3-thiazol-2-yl)piperazine-1-carbonyl]-4-phenylpiperidin-1-yl}prop-2-en-1-one
  • 6-chloro-2-methyl-N-(4-{[1-(prop-2-en-1-yl)piperidin-4-yl]carbamoyl}benzenesulfonyl)pyridine-3-carboxamide
  • 5-(5-Fluoropyridine-3-amido)pyridin-3-yl sulfurofluoridate
  • 5-[(5S)-5-methyl-1,3-oxazolidine-3-carbonyl]pyridin-3-yl sulfurofluoridate
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