1-(Chloroacetyl)-L-proline

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Names

[ CAS No. ]:
23500-10-9

[ Name ]:
1-(Chloroacetyl)-L-proline

[Synonym ]:
L-Proline, 1-(2-chloroacetyl)-
1-(Chloroacetyl)-L-proline
N-chloroacetyl-L-proline
1-chloroacetyl-L-proline
Anagliptin Impurity 1

Chemical & Physical Properties

[ Density]:
1.4±0.1 g/cm3

[ Boiling Point ]:
399.0±37.0 °C at 760 mmHg

[ Molecular Formula ]:
C7H10ClNO3

[ Molecular Weight ]:
191.612

[ Flash Point ]:
195.1±26.5 °C

[ Exact Mass ]:
191.034927

[ PSA ]:
57.61000

[ LogP ]:
-0.46

[ Vapour Pressure ]:
0.0±2.0 mmHg at 25°C

[ Index of Refraction ]:
1.539

Safety Information

[ HS Code ]:
2933990090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • Chloroacetyl chloride
  • Proline
  • Chloroacetic acid
  • H-DL-PRO-NH2

DownStream

  • 1-(Chloroacetyl)-L-prolinamide
  • Vildagliptin (LAF-237)
  • (2S)-1-(Chloroacetyl)-2-pyrrolidinecarbonitrile
  • H-Gly-Pro-OH

Customs

[ HS Code ]: 2933990090

[ Summary ]:
2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Related Compounds

  • (2'S)-Nicotine 1-Oxide
  • 1-(Chloroacetyl)-L-prolinamide
  • 1-(Chloroacetyl)proline
  • N-chloroacetyl-L-proline ethyl ester
  • chloroacetyl L-proline methyl ester
  • ethyl pyrrolidine-2-carboxylate
  • (1R)-2-amino-1-(cyclohex-3-en-1-yl)ethan-1-ol
  • 1-[2-(3-Ethoxy-2-methoxyphenyl)ethyl]cyclopropan-1-amine
  • 2-Amino-1-[2-(difluoromethoxy)-3-methylphenyl]ethan-1-one
  • 5-[3-(dimethylamino)phenyl]-1-methyl-1H-pyrazol-4-amine
  • tert-butyl N-[2-methyl-4-(2,2,2-trifluoro-1-hydroxyethyl)phenyl]carbamate
  • 3-(difluoromethyl)-1-methyl-4-(pyrrolidin-3-yl)-1H-pyrazole
  • tert-butyl N-[1-(1-hydroxycyclopropyl)-4,4-dimethylpentan-3-yl]carbamate
  • 2-Amino-3-(2-{[(tert-butoxy)carbonyl]amino}-4-chlorophenyl)-3-methylbutanoic acid
  • 2-methyl-4-(1H-pyrazol-1-yl)butanal
  • 3-[2-(Dimethylamino)-5-fluorophenyl]-2-oxopropanoic acid
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