1-(Chloroacetyl)-L-proline

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Names

[ CAS No. ]:
23500-10-9

[ Name ]:
1-(Chloroacetyl)-L-proline

[Synonym ]:
L-Proline, 1-(2-chloroacetyl)-
1-(Chloroacetyl)-L-proline
N-chloroacetyl-L-proline
1-chloroacetyl-L-proline
Anagliptin Impurity 1

Chemical & Physical Properties

[ Density]:
1.4±0.1 g/cm3

[ Boiling Point ]:
399.0±37.0 °C at 760 mmHg

[ Molecular Formula ]:
C7H10ClNO3

[ Molecular Weight ]:
191.612

[ Flash Point ]:
195.1±26.5 °C

[ Exact Mass ]:
191.034927

[ PSA ]:
57.61000

[ LogP ]:
-0.46

[ Vapour Pressure ]:
0.0±2.0 mmHg at 25°C

[ Index of Refraction ]:
1.539

Safety Information

[ HS Code ]:
2933990090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • Chloroacetyl chloride
  • Proline
  • Chloroacetic acid
  • H-DL-PRO-NH2

DownStream

  • 1-(Chloroacetyl)-L-prolinamide
  • Vildagliptin (LAF-237)
  • (2S)-1-(Chloroacetyl)-2-pyrrolidinecarbonitrile
  • H-Gly-Pro-OH

Customs

[ HS Code ]: 2933990090

[ Summary ]:
2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Related Compounds

  • (2'S)-Nicotine 1-Oxide
  • 1-(Chloroacetyl)-L-prolinamide
  • 1-(Chloroacetyl)proline
  • N-chloroacetyl-L-proline ethyl ester
  • chloroacetyl L-proline methyl ester
  • ethyl pyrrolidine-2-carboxylate
  • 2',5'-Dichloro-4'-methylphenacyl chloride
  • 1-(4-(2H-1,2,3-triazol-2-yl)piperidin-1-yl)ethanone
  • (4-(2H-1,2,3-triazol-2-yl)piperidin-1-yl)(2,5-dimethylfuran-3-yl)methanone
  • 1-(4-(2H-1,2,3-triazol-2-yl)piperidin-1-yl)-2-(thiophen-2-yl)ethanone
  • (E)-1-(4-(2H-1,2,3-triazol-2-yl)piperidin-1-yl)-3-phenylprop-2-en-1-one
  • 1-(4-(2H-1,2,3-triazol-2-yl)piperidin-1-yl)-2-(m-tolyl)ethanone
  • (4-(2H-1,2,3-triazol-2-yl)piperidin-1-yl)(3-methoxyphenyl)methanone
  • 3-(4-(2H-1,2,3-triazol-2-yl)piperidine-1-carbonyl)-1-methylpyridin-2(1H)-one
  • 1-(4-(2H-1,2,3-triazol-2-yl)piperidin-1-yl)-2-(4-fluorophenyl)ethanone
  • (4-(2H-1,2,3-triazol-2-yl)piperidin-1-yl)(5-chlorothiophen-2-yl)methanone
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