10-Gingerol

Suppliers

Names

[ Name ]:
10-Gingerol

[Synonym ]:
(S)- 5-Hydroxy-1-(4-hydroxy-3-methoxyphenyl)-3-tetradecanone
(5S)-5-Hydroxy-1-(4-hydroxy-3-methoxyphenyl)-3-tetradecanone
(5s)-5-hydroxy-1-(4-hydroxy-3-methoxyphenyl)tetradecan-3-one
<10>-Gingerol
10-Gingerol
3-Tetradecanone, 5-hydroxy-1-(4-hydroxy-3-methoxyphenyl)-, (5S)-

Chemical & Physical Properties

[ Density]:
1.0±0.1 g/cm3

[ Boiling Point ]:
499.7±35.0 °C at 760 mmHg

[ Melting Point ]:
45 - 46 °C

[ Molecular Formula ]:
C₂₁H₃₄O₄

[ Molecular Weight ]:
350.492

[ Flash Point ]:
166.4±19.4 °C

[ Exact Mass ]:
350.245697

[ PSA ]:
66.76000

[ LogP ]:
4.61

[ Vapour Pressure ]:
0.0±1.3 mmHg at 25°C

[ Index of Refraction ]:
1.513

[ Storage condition ]:
2-8°C

[ Water Solubility ]:
methanol: soluble5mg/mL, clear, colorless

MSDS

Click to get detail MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: XB8720000

CHEMICAL NAME :: 3-Tetradecanone, 5-hydroxy-1-(4-hydroxy-3-methoxyphenyl)-, (S)-

CAS REGISTRY NUMBER :: 23513-15-7

LAST UPDATED :: 199503

DATA ITEMS CITED :: 1

MOLECULAR FORMULA :: C21-H34-O4

MOLECULAR WEIGHT :: 350.55

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: >100 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: ZYZAEU Zhongguo Yaoxue Zazhi. Chinese Pharmacuetical Journal. (China International Book Trading Corp., POB 2820, Beijing, Peop. China) V.24- 1989- Volume(issue)/page/year: 25,231,1990

Safety Information

[ Hazard Statements ]:
H413

[ Hazard Codes ]:
T+

[ Risk Phrases ]:
53

[ Safety Phrases ]:
24/25

[ RIDADR ]:
NONH for all modes of transport

[ HS Code ]:
2914509090

Synthetic Route

Click to get detail synthetic route

Customs

[ HS Code ]: 2914509090

[ Summary ]:
HS:2914509090 other ketones with other oxygen function VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:5.5% General tariff:30.0%

Articles

Regioselective glucuronidation of gingerols by human liver microsomes and expressed UDP-glucuronosyltransferase enzymes: reaction kinetics and activity correlation analyses for UGT1A9 and UGT2B7.

J. Pharm. Pharmacol. 67(4) , 583-96, (2015)

To determine the reaction kinetics for regioselective glucuronidation of gingerols (i.e. 6-, 8- and 10-gingerol) by human liver microsomes and expressed UDP-glucuronosyltransferase (UGT) enzymes, and ...

Identification of serotonin 5-HT1A receptor partial agonists in ginger.

Bioorg. Med. Chem. 18 , 3345-51, (2010)

Animal studies suggest that ginger (Zingiber officinale Roscoe) reduces anxiety. In this study, bioactivity-guided fractionation of a ginger extract identified nine compounds that interact with the hu...

Antiallergic potential on RBL-2H3 cells of some phenolic constituents of Zingiber officinale (ginger).

J. Nat. Prod. 72 , 950-3, (2009)

In the present study on five pure phenolic compounds (1-5) isolated from the rhizomes of Zingiber officinale (ginger) and investigated for their antiallergic potency, rat basophilic leukemia (RBL-2H3)...

5-Ethoxy-10-Gingerol
5-Hydroxy-1-(4-hydroxy-3-methoxyphenyl)-3-tetradecanone
10-BROMO-2,3-DIMETHYLANTHRACENE
10,11-dehydro-2-acetoxytrimipramine
10-cyclohexyl-10H-anthracen-9-one
10,12-Pentadecadien-1-ol
1-(((4-Hydroxy-4,5,6,7-tetrahydrobenzofuran-4-yl)methyl)amino)-2-methyl-1-oxopropan-2-yl acetate
N-[(6-cyclopropylpyridin-3-yl)methyl]-2,1,3-benzothiadiazole-5-carboxamide
4-(2,1,3-Benzothiadiazole-5-carbonyl)-1-(1,3-thiazol-2-yl)piperazin-2-one
N-((4-hydroxy-4,5,6,7-tetrahydrobenzofuran-4-yl)methyl)-7-methoxybenzofuran-2-carboxamide
4-methoxy-1-methyl-N-[(oxan-4-yl)(thiophen-2-yl)methyl]-6-oxo-1,6-dihydropyridine-3-carboxamide
2-Oxo-2-(4-(tetrahydrofuran-3-yl)-1,4-diazepan-1-yl)ethyl acetate
2-Oxo-2-(4-(tetrahydrothiophen-3-yl)-1,4-diazepan-1-yl)ethyl acetate
1-(4-{[3-(1H-pyrazol-1-yl)-8-azabicyclo[3.2.1]octan-8-yl]sulfonyl}phenyl)pyrrolidine-2,5-dione
4,5-Dimethyl-6-((1-tosylpiperidin-4-yl)methoxy)pyrimidine
4-(2-Ethylbenzo[d]thiazole-6-carbonyl)-1-(pyridin-2-yl)piperazin-2-one

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