4-Bromo-2-fluoroanisole

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Names

[ CAS No. ]:
2357-52-0

[ Name ]:
4-Bromo-2-fluoroanisole

[Synonym ]:
3-fluoro-4-methoxybromobenzene
Benzene, 4-bromo-2-fluoro-1-methoxy-
4-Bromo-2-fluorophenyl methyl ether
4-brom-2-fluor-1-methoxybenzol
4-BROMO-2-FLUOROPHENYLMETHYL ETHER
p-bromo-o-fluoroanisole
4-Bromo-2-fluoroanisole
FR CE FO1
Benzene,4-bromo-2-fluoro-1-methoxy
3,4-Difluorobenzoic acid
MFCD00011710
2-fluoro-4-bromo anisole
EINECS 219-096-2
1-Bromo-3-fluoro-4-methoxybenzene
4-Bromo-2-fluoro-1-methoxybenzene
3-fluoro-4-methoxy-1-bromobenzene
1H-Indene-1-carboxylicacid,2,3-dihydro-6-nitro-,(+)-(9CI)

Chemical & Physical Properties

[ Density]:
1.5±0.1 g/cm3

[ Boiling Point ]:
215.1±20.0 °C at 760 mmHg

[ Melting Point ]:
16 °C

[ Molecular Formula ]:
C7H6BrFO

[ Molecular Weight ]:
205.024

[ Flash Point ]:
98.3±0.0 °C

[ Exact Mass ]:
203.958603

[ PSA ]:
9.23000

[ LogP ]:
3.16

[ Vapour Pressure ]:
0.2±0.4 mmHg at 25°C

[ Index of Refraction ]:
1.519

[ Water Solubility ]:
insoluble

MSDS

Click to get detail MSDS

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H315-H319-H335

[ Precautionary Statements ]:
P261-P305 + P351 + P338

[ Personal Protective Equipment ]:
Eyeshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter

[ Hazard Codes ]:
Xi:Irritant

[ Risk Phrases ]:
R36/37/38

[ Safety Phrases ]:
S26-S36-S24/25

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

[ HS Code ]:
2909309090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • 2-Fluoroanisole
  • 4-Bromo-2-fluorophenol
  • methyl iodide
  • 3-Fluoro-4-methoxyaniline
  • 4-Bromoanisole

DownStream

  • 2-fluoro-1-methoxy-4-phenylbenzene
  • 3-Fluoro-4-methoxybenzoyl chloride
  • 3-Fluoro-4-(octyloxy)benzoic acid
  • 3-Fluoro-4-methoxybenzonitrile
  • 3-Fluoro-4-hydroxybenzoic acid
  • 3-Fluoro-4-methoxybenzoic acid
  • 2-Fluoro-4-methoxybenzonitrile
  • 2-Fluoro-4-hydroxybenzonitrile
  • 1-(3-fluoro-4-methoxyphenyl)propan-1-one
  • 4-Bromo-2-fluorophenol

Customs

[ HS Code ]: 2909309090

[ Summary ]:
2909309090 other aromatic ethers and their halogenated, sulphonated, nitrated or nitrosated derivatives VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:5.5% General tariff:30.0%

Articles

CYP 17 and CYP 19 inhibitors. Evaluation of fluorine effects on the inhibiting activity of regioselectively fluorinated 1-(Naphthalen-2-ylmethyl)imidazoles.

J. Enzyme Inhib. Med. Chem. 19(2) , 145-55, (2004)

Regioselectively fluorinated 1-(naphth-2-ylmethyl)imidazoles 1a-h have been synthesized starting from the corresponding (naphth-2-yl)methanols (2). 2a-d have been obtained by LiAlH4-promoted reduction...

Design of molecular architectures for polymeric mesophase formation. Pugh C, et al.

Macromol. Symp. 98(1) , (1995)

Syntheses of Phenylbicyclohexane Liquid Crystals with Terminal Difluoromethoxy Group [J]. Li J, et al.

Fine Chemicals 12 , 004, (2004)


More Articles

Related Compounds

  • 5-bromo-1-chloro-3-fluoro-2-methoxybenzene
  • 4-BROMO-2-FLUORO-3'-(4-METHYLPIPERAZINOMETHYL) BENZOPHENONE
  • 4-bromo-2-methanidyl-1-methoxybenzene,chlorozinc(1+)
  • 4-Bromo-2-chloro-3-pyridinol
  • 4-bromo-2-(difluoromethyl)pyridine
  • 4-bromo-2-chloro-5-(trifluoromethyl)pyridine