PROTAC B-Raf degrader 1

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Names

[ CAS No. ]:
2364367-27-9

[ Name ]:
PROTAC B-Raf degrader 1

[Synonym ]:
Glycinamide, N-[2-methoxy-5-[[[(E)-2-(2,4,6-trimethoxyphenyl)ethenyl]sulfonyl]methyl]phenyl]glycyl-N-[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]-
N-[2-Methoxy-5-({[(E)-2-(2,4,6-trimethoxyphenyl)vinyl]sulfonyl}methyl)phenyl]glycyl-N-[2-(2,6-dioxo-3-piperidinyl)-1,3-dioxo-2,3-dihydro-1H-isoindol-4-yl]glycinamide

Chemical & Physical Properties

[ Density]:
1.5±0.1 g/cm3

[ Boiling Point ]:
1136.9±65.0 °C at 760 mmHg

[ Molecular Formula ]:
C36H37N5O12S

[ Molecular Weight ]:
763.770

[ Flash Point ]:
641.4±34.3 °C

[ Exact Mass ]:
763.215942

[ LogP ]:
0.91

[ Vapour Pressure ]:
0.0±0.3 mmHg at 25°C

[ Index of Refraction ]:
1.643

[ Storage condition ]:
-20°C

Related Compounds

  • PROTAC CRABP-II Degrader-1
  • Compound 23
  • PROTAC VEGFR-2 degrader-1
  • PROTAC CDK2/9 Degrader-1
  • PROTAC ERα Y537S degrader-1
  • PROTAC K-Ras Degrader-1
  • 5-[3-methoxy-4-(trifluoromethyl)phenyl]-1H-pyrazole-3-carboxylic acid
  • 3-[2-(Dimethylamino)-4-methyl-1,3-thiazol-5-yl]-2-hydroxypropanoic acid
  • 2,2-Dimethyl-1-(quinolin-6-yl)cyclopropane-1-carboxylic acid
  • 2-{4H,5H,6H-cyclopenta[b]thiophen-2-yloxy}acetic acid
  • 2-(4-Chlorothiophen-2-yl)propanoic acid
  • 3-Hydroxy-1-[3-(trifluoromethyl)pyridin-4-yl]cyclobutane-1-carboxylic acid
  • 1-(1-ethyl-1H-pyrazol-4-yl)-4-hydroxycyclohexane-1-carboxylic acid
  • 1-[1-(Ethoxycarbonyl)piperidin-4-yl]-2,2-difluorocyclopropane-1-carboxylic acid
  • 1-methyl-3-(4-methylthiophen-3-yl)-1H-pyrazole-5-carboxylic acid
  • 3-(4-Ethylcyclohexyl)-2-hydroxy-2-methylpropanoic acid
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