PROTAC B-Raf degrader 1

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Names

[ Name ]:
PROTAC B-Raf degrader 1

[Synonym ]:
Glycinamide, N-[2-methoxy-5-[[[(E)-2-(2,4,6-trimethoxyphenyl)ethenyl]sulfonyl]methyl]phenyl]glycyl-N-[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]-
N-[2-Methoxy-5-({[(E)-2-(2,4,6-trimethoxyphenyl)vinyl]sulfonyl}methyl)phenyl]glycyl-N-[2-(2,6-dioxo-3-piperidinyl)-1,3-dioxo-2,3-dihydro-1H-isoindol-4-yl]glycinamide

Chemical & Physical Properties

[ Density]:
1.5±0.1 g/cm3

[ Boiling Point ]:
1136.9±65.0 °C at 760 mmHg

[ Molecular Formula ]:
C₃₆H₃₇N₅O₁₂S

[ Molecular Weight ]:
763.770

[ Flash Point ]:
641.4±34.3 °C

[ Exact Mass ]:
763.215942

[ LogP ]:
0.91

[ Vapour Pressure ]:
0.0±0.3 mmHg at 25°C

[ Index of Refraction ]:
1.643

[ Storage condition ]:
-20°C

Related Compounds

PROTAC CRABP-II Degrader-1
Compound 23
PROTAC VEGFR-2 degrader-1
PROTAC CDK2/9 Degrader-1
PROTAC ERα Y537S degrader-1
PROTAC K-Ras Degrader-1
(S)-1-(5-(Difluoromethyl)-2-fluorophenyl)butan-1-amine
1-(Difluoromethyl)-1H-pyrazole-4-sulfonyl fluoride
(R)-1-(3-Methoxy-4-methylphenyl)but-3-en-1-amine
1-Fluoro-3-nitro-5-(trifluoromethoxy)benzene
(R)-1-(3-methoxy-2-methylphenyl)butan-1-amine
Methyl 2-(trifluoromethyl)-1H-imidazole-5-carboxylate
rel-2-(2-Ethylphenoxy)-1-((2R,4S)-4-methoxy-2-(4-methyl-4H-1,2,4-triazol-3-yl)pyrrolidin-1-yl)ethan-1-one
tert-Butyl 3-fluoro-1H-pyrazolo[3,4-c]pyridine-1-carboxylate
Methyl 2-amino-5-isobutyl-4-methylthiophene-3-carboxylate
4-Amino-7-methylchromane-6-carboxylic acid hydrochloride