PROTAC B-Raf degrader 1

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Names

[ CAS No. ]:
2364367-27-9

[ Name ]:
PROTAC B-Raf degrader 1

[Synonym ]:
Glycinamide, N-[2-methoxy-5-[[[(E)-2-(2,4,6-trimethoxyphenyl)ethenyl]sulfonyl]methyl]phenyl]glycyl-N-[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]-
N-[2-Methoxy-5-({[(E)-2-(2,4,6-trimethoxyphenyl)vinyl]sulfonyl}methyl)phenyl]glycyl-N-[2-(2,6-dioxo-3-piperidinyl)-1,3-dioxo-2,3-dihydro-1H-isoindol-4-yl]glycinamide

Chemical & Physical Properties

[ Density]:
1.5±0.1 g/cm3

[ Boiling Point ]:
1136.9±65.0 °C at 760 mmHg

[ Molecular Formula ]:
C36H37N5O12S

[ Molecular Weight ]:
763.770

[ Flash Point ]:
641.4±34.3 °C

[ Exact Mass ]:
763.215942

[ LogP ]:
0.91

[ Vapour Pressure ]:
0.0±0.3 mmHg at 25°C

[ Index of Refraction ]:
1.643

[ Storage condition ]:
-20°C

Related Compounds

  • PROTAC CRABP-II Degrader-1
  • Compound 23
  • PROTAC VEGFR-2 degrader-1
  • PROTAC CDK2/9 Degrader-1
  • PROTAC ERα Y537S degrader-1
  • PROTAC K-Ras Degrader-1
  • 4-(3-Bromo-5-fluoro-benzyl)-2-methyl-piperazine-1-carboxylic acid tert-butyl ester
  • (2R)-4-(3-Bromo-5-fluorobenzyl)-2-methylpiperazine-1-carboxylic acid tert-butyl ester
  • 1-(3-Bromo-5-fluoro-benzyl)-3,3-difluoro-piperidine
  • tert-Butyl (1-(3-bromo-5-fluorophenyl)propyl)carbamate
  • 3-(3-Bromobenzenesulfonylmethyl)-azetidine-1-carboxylic acid tert-butyl ester
  • [3-(3-Bromo-benzenesulfonyl)-propyl]-carbamic acid tert-butyl ester
  • 4-Hydroxy-6,7-dihydro-1,2-benzoxazole-3-carboxylic acid
  • (1S,4S)-2-(3-Methylpyridin-4-yl)-2,5-diazabicyclo[2.2.1]heptane
  • Sodium 6-chloro-5-fluoropyridine-3-sulfinate
  • Sodium5-chloropyrimidine-2-sulfinate
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