PROTAC B-Raf degrader 1

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Names

[ CAS No. ]:
2364367-27-9

[ Name ]:
PROTAC B-Raf degrader 1

[Synonym ]:
Glycinamide, N-[2-methoxy-5-[[[(E)-2-(2,4,6-trimethoxyphenyl)ethenyl]sulfonyl]methyl]phenyl]glycyl-N-[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]-
N-[2-Methoxy-5-({[(E)-2-(2,4,6-trimethoxyphenyl)vinyl]sulfonyl}methyl)phenyl]glycyl-N-[2-(2,6-dioxo-3-piperidinyl)-1,3-dioxo-2,3-dihydro-1H-isoindol-4-yl]glycinamide

Chemical & Physical Properties

[ Density]:
1.5±0.1 g/cm3

[ Boiling Point ]:
1136.9±65.0 °C at 760 mmHg

[ Molecular Formula ]:
C36H37N5O12S

[ Molecular Weight ]:
763.770

[ Flash Point ]:
641.4±34.3 °C

[ Exact Mass ]:
763.215942

[ LogP ]:
0.91

[ Vapour Pressure ]:
0.0±0.3 mmHg at 25°C

[ Index of Refraction ]:
1.643

[ Storage condition ]:
-20°C

Related Compounds

  • PROTAC CRABP-II Degrader-1
  • Compound 23
  • PROTAC VEGFR-2 degrader-1
  • PROTAC CDK2/9 Degrader-1
  • PROTAC ERα Y537S degrader-1
  • PROTAC K-Ras Degrader-1
  • 1-[(2,4-Difluorophenyl)methyl]-3-(piperidine-1-carbonyl)piperidine
  • 4-{1-[(2-Chloro-6-fluorophenyl)methyl]pyrrolidine-3-carbonyl}thiomorpholine
  • 8-Bromo-2,3-dihydro-3-methyl-5(1H)-indolizinone
  • 3-Cyclobutyl-5-(5,5-dimethyl-1,3,2-dioxaborinan-2-yl)-2-methoxy-pyridine
  • Methyl 4-(1-aminoethyl)oxane-4-carboxylate
  • tert-butyl N-[4-(3-hydroxy-2,2-dimethylpropyl)-2-methylphenyl]carbamate
  • 4-[5-Fluoro-2-(trifluoromethyl)phenyl]-2-methylbutan-2-amine
  • 1-(1-Benzylpyrrolidin-2-yl)-2,2-dimethylcyclopropan-1-amine
  • 2-methyl-1-(3-phenyl-1H-pyrazol-4-yl)propan-2-ol
  • tert-butyl 3-(5-amino-1H-1,2,3-benzotriazol-1-yl)azetidine-1-carboxylate
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