1H-Indole-2,3-dione,3-hydrazone

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Names

[ CAS No. ]:
2365-44-8

[ Name ]:
1H-Indole-2,3-dione,3-hydrazone

[Synonym ]:
isatin monohydrazone
1H-indole-2,3-dione 3-hydrazone
3-Hydrazono-1,3-dihydro-indol-2-one
Isatin 3-hydrazone
INDOLE-2,3-DIONE,3-HYDRAZONE
3-Hydrazono-2-indolinone
hydrazono-2-indolinone
3-hydrazonoindolin-2-one

Chemical & Physical Properties

[ Density]:
1.49 g/cm3

[ Boiling Point ]:
424.8ºC at 760 mmHg

[ Molecular Formula ]:
C8H7N3O

[ Molecular Weight ]:
161.16100

[ Flash Point ]:
210.7ºC

[ Exact Mass ]:
161.05900

[ PSA ]:
67.48000

[ LogP ]:
1.13980

[ Vapour Pressure ]:
2.01E-07mmHg at 25°C

[ Index of Refraction ]:
1.734

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
NL7930500
CHEMICAL NAME :
Indole-2,3-dione, 3-hydrazone
CAS REGISTRY NUMBER :
2365-44-8
BEILSTEIN REFERENCE NO. :
0137064
LAST UPDATED :
199612
DATA ITEMS CITED :
1
MOLECULAR FORMULA :
C8-H7-N3-O
MOLECULAR WEIGHT :
161.18

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
873 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
ABMGAJ Acta Biologica et Medica Germanica. (Berlin, Ger. Dem. Rep.) V.1-41, 1958-82. For publisher information, see BBIADT. Volume(issue)/page/year: 14,158,1965

Safety Information

[ HS Code ]:
2933990090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • isatin
  • 2-(2-oxo-1H-indol-3-ylidene)propanedinitrile
  • 1,3-dihydro-3-hydroxy-3-(2-oxo-2-phenylethyl)-2H-indol-2-one
  • Hydrazine hydrate
  • Anisole
  • Isoindigotin

DownStream

  • Oxindole
  • isatin
  • Nitrogen
  • 3-Diazoindol-2(3H)-one
  • Benzaldehyde,2-hydroxy-, 2-(1,2-dihydro-2-oxo-3H-indol-3-ylidene)hydrazone
  • 2-[(2-oxoindol-3-yl)amino]isoindole-1,3-dione

Customs

[ HS Code ]: 2933990090

[ Summary ]:
2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Related Compounds

  • 3-hydrazinyl-5-iodoindol-2-one
  • 1H-Indole-2,3-dione, 3-[(2-nitrophenyl)hydrazone]
  • 1H-Indole-2,3-dione,3-[2-(4-nitrophenyl)hydrazone]
  • 1H-Indole-2,3-dione,3-[2-(2-pyridinyl)hydrazone]
  • 1H-Indole-2,3-dione,3-[2-(2-methoxyphenyl)hydrazone]
  • 1H-Indole-2,3-dione,1-hydroxy-, 3-hydrazone
  • ethyl 1-[(1-ethyl-1H-pyrazol-4-yl)methyl]piperidine-4-carboxylate
  • 1-[(4-chloro-1H-pyrazol-1-yl)methyl]-3,5-dimethyl-1H-pyrazol-4-amine
  • N-(3-(Hydrazinecarbonyl)phenyl)acetamide
  • Ethyl 7-methyl-2-oxo-1,2-dihydropyrazolo[1,5-a]pyridine-6-carboxylate
  • 2-(1-(4-fluorobenzyl)-1H-1,2,4-triazol-3-yl)-4,5-dimethoxyisoindoline-1,3-dione
  • [7-(1-ethyl-5-methyl-1H-pyrazol-4-yl)pyrazolo[1,5-a]pyrimidin-3-yl][7-(trifluoromethyl)-6,7-dihydropyrazolo[1,5-a]pyrimidin-4(5H)-yl]methanone
  • 7-(((2-Chlorophenyl)amino)(phenyl)methyl)quinolin-8-ol
  • N-(3-cyano-4,5-dimethylthiophen-2-yl)-4-methyl-2-(pyridin-3-yl)-1,3-thiazole-5-carboxamide
  • N-[1-(1-ethyl-1H-pyrazol-3-yl)ethyl]-1-methyl-3-(trifluoromethyl)-1H-thieno[2,3-c]pyrazole-5-carboxamide
  • 5-Ethyl-N-(1-ethyl-3-methyl-1H-pyrazol-5-yl)-3-thiophenecarboxamide
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